Structural studies of human autoantibodies: Crystal structure of a thyroid peroxidase autoantibody Fab

Journal of Biological Chemistry

Volumn 271, Issue 21, 1996, Pages 12191-12198

  Chacko, Susan ^a   Padlan, Eduardo A ^a   Portolano, Stefano ^b,c   McLachlan, Sandra M ^b,c   Rapoport, Basil ^b,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; THYROID ANTIBODY; THYROID PEROXIDASE;

ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AUTOANTIBODIES; CRYSTALLOGRAPHY, X-RAY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IODIDE PEROXIDASE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 15844387253     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.21.12191     Document Type: Article

References (48)

1. McLachlan, S. M., and Rapoport, B. (1992) Endocr. Rev. 13, 192-206
2. Portolano, S., Seto, P., Chazenbalk, G. D., Nagayama, Y., McLachlan, S. M., and Rapoport, B. (1991) Biochem. Biophys. Res. Commun. 179, 372-377
3. Portolano S., Chazenbalk, G. D., Seto, P., Hutchison, J. S., Rapoport, B., and McLachlan, S. M. (1992) J. Clin. Invest. 90, 720-726
4. Portolano, S., Chazenbalk, G. D., Hutchison, J. S., McLachlan, S. M., and Rapoport, B. (1993) J. Immunol. 150, 880-887
5. Chazenbalk, G. D., Portolano, S., Russo, D., Hutchison, J. S., Rapoport, B., and McLachlan, S. (1993) J. Clin. Invest. 92, 62-74
6. Portolano, S., McLachlan, S. M., and Rapoport, B. (1993) J. Immunol. 151, 2839-2851
7. Prummel, M. F., Portolano, S., Costante, G., Rapoport, B., and McLachlan, S. M. (1994) Mol. Cell. Endocrinol. 102, 161-166
8. Nishikawa, T., Costante, G., Prummel, M. F., McLachlan, S. M., and Rapoport, B. (1994) J. Clin. Endocrinol. Metab. 78, 944-949
9. Jaume, J. C., Parkes, A. B., Lazarus, J. H., Hall, R., Costante, G., McLachlan, S. M., and Rapoport, B. (1995) J. Clin. Endocrinol. Metab. 80, 1000-1005
10. Rapoport, B., Portolano, S., and McLachlan, S. M. (1995) Immunol. Today 16, 43-49
11. Pascual, V., Victor, K., Rander, I., Natvig, J. B., and Capra, J. D. (1992) J. Rheumatol. 19, Suppl. 23, 50-53
12. Padlan, E. A. (1994) Mol. Immunol. 31, 169-217
13. Posner, B., Lee, I., Itoh, T., Pyati, J., Graff, R., Thorton, G. B., La Polla, R., and Benkovic, S. J. (1993) Gene (Amst.) 128, 111-117
14. Jancarik, J., and Kim, S. H. (1991) J. Appl. Cryst. 24, 409-411
15. Kabsch, W. (1993) J. Appl. Cryst. 26, 795-800
16. Navaza, J. (1994) Acta Cryst. A50, 157-163
17. He, X. M., Rueker, F., Casale, E., and Carter, D. C. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7154-7158
18. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F., Jr, Brice, M. D., Rodgers, J. R., Kennard, O., Shimanouchi, T., and Tasumi, M. (1977) J. Mol. Biol. 112, 535-542
19. Abola, E. E., Bernstein, F. C., Bryant, S. H., Koetzle, T. F., and Weng, J. (1987) in Crystallographic Databases: Information Content, Software Systems, Scientific Applications (Allen, F. C., Bergerhoff, G., and Sievers, R., eds) pp. 107-132, Data Commission of the International Union of Crystallography, Bonn
20. Bruenger, A. T. (1992) X-PLOR: A System For Crystallography and NMR, Version 3.1, Yale University Press, New Haven, CT
21. Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C. (1991) Sequences of Proteins of Immunological Interest, 5th Ed., United States Department of Health and Human Services, Public Health Service, National Institutes of Health, NIH Publication No. 91-3242
22. Jones, A. T. (1985) Methods Enzymol. 115, 157-171
23. Sasisekharan, V. (1962) in Collagen (Ramanathan, N., ed) pp. 39-77, John Wiley, New York
24. Luzzati, V. (1953) Acta Cryst. 6, 142-152
25. Davies, D. R., Sheriff, S., Padlan, E. A., Silverton, E. W., Cohen, G. H., and Smith-Gill, S. J. (1989) in The Immune Response to Structurally Defined Proteins: The Lysozyme Model (Smith-Gill, S. J., and Sercarz, E. E., eds) pp. 125-132, Adenine Press, Guilderland, NY
26. Wilson, I. A., and Stanfield, R. L. (1994) Curr. Opin. Struct. Biol. 4, 857-867
27. Connolly, M. L. (1983) J. Appl. Crystallogr. 16, 548-558
28. Padlan, E. A. (1994) Antibody-Antigen Complexes, R. G. Landes, Austin
29. Chothia, C., Lesk, A. M., Tramontano, A., Levitt, M., Smith-Gill, S. J., Air, G., Sheriff, S., Padlan, E. A., Davies, D., Tulip, W. R., Colman, P. M., Spinelli, S., Alzari, P. M., and Poljak, R. J. (1989) Nature 342, 877-883
30. Fan, Z., Shan, L., Guddat, L. W., He, X., Gray, W. R., Raison, R. L., and Edmundson, A. B. (1992) J. Mol. Biol. 228, 188-207
31. Epp, O., Lattman, E. E., Schiffer, M., Huber, R., and Palm, W. (1975) Biochemistry 14, 4943-4952
32. Huang, D.-B., Chang, C.-H., Ainsworth, C., Brünger, A. T., Eulitz, M., Solomon, A., Stevens, F. J., and Schiffer, M. (1994) Biochemistry 33, 14848-14857
33. Saul, F. A., and Poljak, R. J. (1992) Proteins Struct. Funct. Genet. 14, 363-371
34. Marquait, M., Deisenhofer, J., Huber, R., and Palm, W. (1980) J. Mol. Biol. 141, 369-391
35. Guddat, L. W., Herron, J. N., and Edmundson, A. B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4271-4275
36. Wilson, K. P., Malcolm, B. A., and Matthews, B. W. (1992) J. Biol. Chem. 267, 10842-10849
37. Rypniewski, W. R., Holden, H. M., and Rayment, I. (1993) Biochemistry 32, 9851-9858
38. Harata, K. (1994) Acta Cryst. D50, 250-257
39. Shin, E. K., Matsuda, F., Nagaoka, H., Fukita, Y., Imai, T., Yokoyama, K., Soeda, E., and Honjo, T. (1991) EMBO J. 10, 3641-3645
40. Tomlinson, I. M., Walter, G., Marks, J. D., Llewelyn, M. B., and Winter, G. (1992) J. Mol. Biol. 227, 776-798
41. Klein, R., Jaenichen, R., and Zachau, H. G. (1994) Eur. J. Immunol. 23, 3248-3271
42. Fersht, A. R., Shi, J.-P., Knill-Jones, J., Lowe, D. M., Wilkinson, A. J., Blow, D. M., Brick, P., Carter, P., Wayne, M. M., and Winter, G. (1985) Nature 314, 235-238
43. Padlan, E. A. (1990) Proteins Struct. Funct. Genet. 7, 112-124
44. Strong, R. K., Campbell, R., Rose, D. R., Petsko, G. A., Sharon, J., and Margolies, M. N. (1991) Biochemistry 30, 3739-3748
45. Eigenbrot, C., Gonzalez, T., Mayeda, J., Carter, P., Werther, W., Hotaling, T., Fox, J., and Kessler, J. (1994) Proteins Struct. Funct. Genet. 18, 49-62
46. Padlan, E. A., Abergel, C., and Tipper, J. P. (1995) FASEB J. 9, 133-139
47. Koshland, D. E., Jr. (1973) Sci. Am. 229, 52-64
48. Edelman, G. M., Cunningham, B. A., Gall, W. E., Gottlieb, P. D., Rutishauser, U., and Waxdal, M. J. (1969) Proc. Natl. Acad. Sci. U. S. A. 63, 78-85