Human blood eosinophils produce and secrete interleukin 4

Respiratory Medicine

Volumn 90, Issue 5, 1996, Pages 271-277

  Bjerke, T ^a,b   Gaustadnes, M ^a   Nielsen, S ^b   Nielsen, L P ^a   Schiotz P O ^a   Rudiger, N ^a   Reimert, C M ^c   Dahl, R ^a   Christensen, I ^b   Poulsen, L K ^c  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMYCIN; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN 4; MESSENGER RNA;

ALLERGIC REACTION; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTE DIFFERENTIATION; MICROSCOPY; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; T LYMPHOCYTE;

EID: 15844381713     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(96)90098-0     Document Type: Article

References (29)

1. Maggi E, Parronchi P, Manetti R et al. Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones. J Immunol 1991; 148: 2142-2146.
2. de Vries JE, Gauchat JF, Aversa GG, Punnonen J, Gascan H, Yssel H. Regulation of IgE synthesis by cytokines. Curr Opin Immunol 1991; 3: 851-858.
3. DeFrance T, Aubry JP, Rousset F et al. Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes. J Exp Med 1987; 165: 1459-1467.
4. Vercelli D, Jabara HH, Lee BW, Woodland N, Geha RS, Leung DY. Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes. J Exp Med 1988; 167: 1406-1416.
5. Postlethwaite AE, Seyer JM. Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122. J Clin Invest 1991; 87: 2147-2152.
6. Dubois GR, Bruijnzeel-Koomen CAFM, Bruijnzeel PLB. IL-4 induces chemotaxis of blood eosinophils from atopic dermatitis patients, but not from normal individuals. J Invest Derm 1994; 102: 843-846.
7. Howard M, Farrar J, Hilfiker M et al. Identification of a T cell-derived B cell growth factor distinct from interleukin 2. J Exp Med 1982; 155: 914-918.
8. Piccinni MP, Macchia D, Parronchi P et al. Human bone marrow non-B, non-T cells produce interleukin 4 in response to cross-linkage of Fc epsilon and Fc gamma receptors. Proc Natl Acad Sci USA 1991; 88: 8656-8660.
9. Bradding P, Feather IH, Howarth PH et al. Interleukin-4 is localized to and released by human mast cells. J Exp Med 1992; 176: 1381-1386.
10. Brunner T, Heusser CH, Dahinden CA. Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation. J Exp Med 1993; 177: 605-611.
11. Bousquet J, Chanzez P, Lacoste JY et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323: 1033-1039.
12. Butterworth AE, Thorne KJI. In Smith H, Cook RM, eds. Immunopharmacology of Eosinophils. 1993. p. 119-126.
13. Wong DTW, Weller PF, Galli SJ et al. Human eosinophils express transforming growth factor alpha. J Exp Med 1990; 172: 673-681.
14. Kita H, Ohnishi T, Okubo Y, Weiler D, Abrams JS, Gleich GJ. Granulocyte/macrophage colonystimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils. J Exp Med 1991; 174: 745-748.
15. Moqbel R, Hamid Q, Ying S et al. Expression of mRNA and immunoreactivity for the granulocyte/ macrophage colony-stimulating factor in activated human eosinophils. J Exp Med 1991; 174: 749-752.
16. Dubucquoi S, Desreumaux P, Janin A et al. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med 1994; 179: 703-708.
17. Braun RK, Franchini M, Erard F et al. Human peripheral blood eosinophils produce and release interleukin-8 on stimulation with calcium ionophore. Eur J Immunol 1993; 23: 956-960.
18. Costa JJ, Matossian K, Resnick MB et al. Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha. J Clin Invest 1993; 91: 2673-2684.
19. Hansel TT, de Vries IJM, Iff T et al. An improved immunomagnetic procedure for the isolation of highly purified human blood eosoniphils. J Immunol Methods 1991; 145: 105-110.
20. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Analyt Biochem 1987; 162: 156-159.
21. Tokuyasu KT. Immunochemistry on ultrathin frozen sections. J Histochem 1980; 12: 381-385.
22. Griffiths G, McDowall A, Back R, Dubochet J. On the preparation of cryosections for immunocytochemistry. J Ultrastruc Res 1984; 89: 65-78.
23. Poulsen LK, Reimert CM, Bindslev Jensen C, Hansen MB, Bendtzen K. Biomolecular regulation of the IgE immune response. II. In vitro IgE synthesis and spontaneous production of cytokines. Int Arch Allergy Appl Immunol 1995; 106: 55-61.
24. MacGlashan Jr D, White JM, Huang SK, Ono SJ, Schroeder JT, Lichtenstein LM. Secretion of Il-4 from human basophils. The relationship between Il-4 mRNA and protein in resting and stimulated basophils. J Immunol 1994; 152: 3006-3016.
25. Kelso A, Metcalf D. T lymphocyte-derived colonystimulating factors. Adv Immunol 1990; 48: 69-105.
26. Bradding P, Roberts JA, Britten KM et al. Interleukin-4, -5 and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994; 10: 471-480.
27. Brusselle GG, Kips JC, Tavernier JH et al. Attenuation of allergic airway inflammation in Il-4 deficient mice. Clin Exp Allergy 1994; 24: 73-80.
28. Robinson D, Hamid Q, Bentley A, Ying S, Kay AB, Durham SR. Activation of CD4+T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993; 92: 313-324.
29. Gauchat JF, Henchoz S, Mazzei G et al. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 1993; 365: 340-343.