Autoreactive cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected subjects

Journal of Experimental Medicine

Volumn 183, Issue 6, 1996, Pages 2509-2516

  Di Marzo Veronese, Fulvia ^a   Arnott, David ^b   Barnaba, Vincenzo ^c   Loftus, Douglas ^a   Sakaguchi, Kazuyasu ^a   Thompson, Cynthia Boyer ^d   Salemi, Simonetta ^c   Mastroianni, Claudio ^c   Sette, Alessandro ^e   Shabanowitz, Jeffrey ^b   Hunt, Donald F ^b   Appella, Ettore ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d ADVANCED BIOSCIENCE LABORATORIES INC   (United States)

^e CYTEL CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A2 ANTIGEN; VINCULIN;

ANTIGEN RECOGNITION; ARTICLE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR HISTOCOMPATIBILITY COMPLEX; PATHOGENESIS; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; B-LYMPHOCYTES; BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HIV INFECTIONS; HIV-1; HLA-A2 ANTIGEN; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDES; REFERENCE VALUES; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; VINCULIN; VIRAL PROTEINS;

EID: 15844380374     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.6.2509     Document Type: Article

References (25)

1. Taylor, P.M., and B.A. Askonas. 1986. Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo. Immunology. 58:417-420.
2. Young, D.F., R.E. Randall, J.A. Hoyle, and B.E. Souberbielle. 1990. Clearance of a persistent paramyxovirus infection is mediated by cellular immune responses but not by serum-neutralizing antibody. J. Virol. 64:5403-5411.
3. Walker, B.D., and F. Plata. 1990. Cytotoxic T lymphocytes against HIV. AIDS. 4:177-184.
4. + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68: 6103-6110.
5. Koup, R.A., J.T. Safrit, Y. Cao, C.A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D.D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
6. Schrager, L.K., J.M. Young, M.G. Fowler, B.J. Mathieson, and S.H. Vermund. 1994. Long-term survivors of HIV-1 infection: definitions and research challenges. AIDS. 8(Suppl.): S95-S108.
7. Koenig, S., A.J. Conley, Y.A. Brewah, G.M. Jones, S. Leath, L.J. Boots, V. Davey, G. Pantaleo, J.F. Demarest, C. Carter, et al. 1995. Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. Nature Medicine. 1:330-336.
8. Zinkernagel, R.M., and H. Hengartner. 1994. T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS. Immunol. Today. 15:262-268.
9. Chaffee, S., J.M. Leeds, T.J. Matthews, K.J. Weinhold, M. Skinner, D.P. Bolognesi, and M.S. Hershfield. 1988. Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines. J. Exp. Med. 168:605-621.
10. Hunt, D.F., R.A. Henderson, J. Shabanowitz, K. Sakaguchi, H. Michel, N. Sevilir, A.L. Cox, E. Appella, and V.H. Engelhard. 1992. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science (Wash. DC). 255:1261-1266.
11. Barnaba, V., A. Franco, A. Alberti, R. Benvenuto, and F. Balsano. 1990. Selective killing of hepatitis B envelope antigen-specific B cells by class 1-restricted, exogenous antigen-specific T lymphocytes. Nature (Lond.). 345:258-260.
12. Imanishi, T., T. Akaza, A. Kimura, K. Tokunaga, and T. Gojobori. 1992. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups. In HLA 1991, Proceedings of the Eleventh International Histocompatibility Workshop and Conference. K. Tsuji, M. Aizawa, and T. Sasazuki, editors. Oxford University Press, Tokyo. 1066-1077.
13. Dahl, K., T. Burrage, F. Jones, and G. Miller. 1990. Persistent non-productive infection of Epstein-Barr virus-transformed human B lymphocytes by human immunodeficiency virus type 1. J. Virol. 64:1771-1783.
14. Henderson, E.E., J.Y. Yang, R.D. Zhang, and M. Bealer. 1991. Altered HIV expression and EBV-induced transformation in coinfected PBLs and PBL subpopulations. Virology. 182:186-198.
15. Poznansky, M.C., B. Walker, W.A. Haseltine, J. Sodroski, and E. Langhoff. 1991. A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA. J. AIDS. 4:368-373.
16. Ruppert, J., J. Sidney, E. Celis, R.T. Kubo, H.M. Grey, and A. Sette. 1993. Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell. 74:929-937.
17. Gumbiner, B.M. 1993. Proteins associated with the cytoplasmic surface of adhesion molecules. Neuron. 11:551-564.
18. Weller, P.A., E.P. Ogryzko, E.B. Corben, N.I. Zhidkova, B. Patel, G.J. Price, N.K. Spurr, V.E. Koteliansky, and D.R. Critchley. 1990. Complete sequence of human vinculin and assignment of the gene to chromosome 10. Proc. Natl. Acad. Sci. USA. 87:5667-5671.
19. Sastry, K.J., R.H.R. Reddy, R. Pandita, K. Totpal, and B.B. Aggrawal. 1990. HIV-1 tat gene induces tumor necrosis factor-β (lymphotoxin) in a human B-lymphoblastoid cell line. J. Biol. Chem. 265:20091-20093.
20. Han, P., R. Brown, and J. Barsoum. 1991. Transactivation of heterologous promoters by HIV-1 tat. Nucleic Acids Res. 19: 7225-7229.
21. Taylor, J.P., C. Cupp, M. Chowdhury, K. Khalili, S.A. Jimenez, and S. Amini. 1992. Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proc. Natl. Acad. Sci. USA. 89:9617-9621.
22. van der Bruggen, P., C. Traversari, P. Chomez, C. Lurguin, E. De Plaen, B. van den Eynde, A. Knuth, and T. Boon. 1991. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (Wash. DC). 254:1643-1647.
23. Gaugler, B., B. van den Eynde, P. van der Bruggen, P. Romero, J.J. Gaforio, E. De Plaen, B. Lethe, F. Brasseur, and T. Boon. 1994. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med. 179:921-930.
24. Salemi, S., A.P. Caporossi, L. Boffa, M.G. Longobardi, and V. Barnaba. 1995. HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing. J. Exp. Med. 181:2253-2257.
25. Sercarz, E.E., P.V. Lehmann, A. Ametani, G. Benichou, A. Miller, and K. Moudgil. 1993. Dominance and crypticity of T cell antigenic determinants. Annu. Rev. Immunol. 11:729-766.