Radioguided surgery of primary hyperparathyroidism using the low-dose 99mTc-sestamibi protocol: Multiinstitutional experience from the Italian Study Group on Radioguided Surgery and Immunoscintigraphy (GISCRIS)

Journal of Nuclear Medicine

Volumn 46, Issue 2, 2005, Pages 220-226

  Rubello, Domenico ^a   Pelizzo, Maria Rosa ^b   Boni, Giuseppe ^c   Schiavo, Riccardo ^d   Vaggelli, Luca ^e   Villa, Giuseppe ^f   Sandrucci, Sergio ^g   Piotto, Andrea ^b   Manca, Gianpiero ^c   Marini, Pierluigi ^d   Mariani, Giuliano ^c  

^a S MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^b UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d SAN CAMILLO FORLANINI HOSPITAL   (Italy)

^e CAREGGI UNIVERSITY HOSPITAL   (Italy)

^f UNIVERSITY OF GENOA   (Italy)

^g UNIVERSITY OF TURIN   (Italy)

Author keywords

99mTc sestamibi scintigraphy; Minimally invasive parathyroidectomy; Neck ultrasonography; Primary hyperparathyroidism; Radioguided surgery; Solitary parathyroid adenoma

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PARATHYROID HORMONE; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPOCALCEMIA; IMMUNOSCINTIGRAPHY; ITALY; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MECHANICAL PROBE; MINIMALLY INVASIVE SURGERY; OPERATION DURATION; PARATHYROID ADENOMA; PARATHYROID CARCINOMA; PARATHYROIDECTOMY; PATIENT SELECTION; PREOPERATIVE EVALUATION; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; RADIOSURGERY; THYROID SURGERY; TREATMENT OUTCOME; CLINICAL TRIAL; COMPUTER ASSISTED SURGERY; EPIDEMIOLOGY; HYPERPARATHYROIDISM; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; POSTOPERATIVE COMPLICATION; SCINTISCANNING; STATISTICS; VALIDATION STUDY;

ADULT; AGED; AGED, 80 AND OVER; CAUSALITY; FEMALE; HUMANS; HYPERPARATHYROIDISM; ITALY; MALE; MIDDLE AGED; PARATHYROIDECTOMY; POSTOPERATIVE COMPLICATIONS; RADIOPHARMACEUTICALS; SURGERY, COMPUTER-ASSISTED; SURGICAL PROCEDURES, MINIMALLY INVASIVE; TECHNETIUM TC 99M SESTAMIBI; TREATMENT OUTCOME;

EID: 15844378084     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Kaplan E, Barlett S, Sugimoto J, Fredland A. Relation of postoperative hypocalcemia to operative technique: deleterious effect of excessive use of parathyroid biopsy. Surgery. 1982;92:827-834.
2. Clark OH. Surgical treatment of primary hyperparathyroidism. Adv Endocrinol Metab. 1995;6:1-16.
3. Tibblin S, Bondeson AG, Ljubgberg O. Unilateral parathyroidectomy in hyperparathyroidism due to a single adenoma. Ann Surg. 1982;195:245-252.
4. Gagner M. Endoscopic parathyroidectomy [letter]. Br J Surg. 1996;83:875.
5. Henry JF, Iacobone M, Mirallie E, Deveze A, Pili S. Indications and results of video-assisted parathyroidectomy by a lateral approach in patients with primary hyperparathyroidism. Surgery. 2001;130:999-1004.
6. Norman J, Chheda H. Minimally invasive parathyroidectomy facilitated by intraoperative nuclear mapping. Surgery. 1997;122:998-1003.
7. 99mTc-MIBI and ultrasound imaging protocol. Eur J Nucl Med. 2000;27:1300-1304.
8. 99mTc-MIBI dose: technical considerations and long-term clinical results. Q J Nucl Med. 2003;47:129-138.
9. Mariani G, Gulec SA, Rubello D, et al. Preoperative localization and radioguided parathyroid surgery. J Nucl Med. 2003;44:1443-1458.
10. 99mTc-Sestamibi: a new agent for parathyroid imaging. Nucl Med Commun. 1989;10:791-794.
11. Taillefer R, Boucher Y, Potvin C, Lambert R. Detection and localization of parathyroid adenomas in patients with hyperparathyroidism using a single radionuclide imaging procedure with technetium-99m-sestamibi (double-phase study). J Nucl Med. 1992;33:1801-1807.
12. O'Doherty MJ, Kettle AG, Wells P, Collins REC, Coakley AJ. Parathyroid imaging with technetium-99m-sestamibi: preoperative localization and tissue uptake studies. J Nucl Med. 1992;33:313-318.
13. Hindié E, Melliere D, Jeanguillaume C, Perlemuter L, Chehade F, Galle P. Parathyroid imaging using simultaneous double-window recording of technetium-99m-sestamibi and iodine-123. J Nucl Med. 1998;39:1100-1105.
14. Rubello D, Saladini G, Casara D, et al. Parathyroid imaging with pertechnetate plus perchlorate/MIBI subtraction scintigraphy: a fast and effective technique. Clin Nucl Med. 2000;25:527-531.
15. Coakley AJ. Symposium on parathyroid localization [editorial]. Nucl Med Commun. 2003;24:111-113.
16. Irvin GL, Dembrow VD, Prudhomme DL. Clinical usefulness of an intraoperative "quick PTH" assay. Surgery. 1993;114:1019-1023.
17. 4/MIBI scan, ultrasound and intra-operative gamma probe in the performance of unilateral and minimally invasive surgery in primary hyperparathyroidism. Eur J Nucl Med. 2001;28:1351-1359.
18. Rubello D, Pelizzo MR, Casara D. Nuclear medicine and minimally invasive surgery of parathyroid adenomas: a fair marriage [editorial]. Eur J Nucl Med. 2002;30:189-192.
19. Rubello D, Casara D, Pelizzo MR. Symposium on parathyroid localising imaging: optimization of peroperative procedures. Nucl Med Commun. 2003;24:133-140.
20. Rubello D, Casara D, Shapiro B. Recent advances in preoperative and intraoperative nuclear medicine procedures in patients with primary hyperparathyroidism. Panminerva Med. 2002;44:99-105.
21. Rubello D, Piotto A, Casara D, Muzzio PC, Shapiro B, Pelizzo MR. Role of gamma probes in performing minimally invasive parathyroidectomy in patients with primary hyperparathyroidism: optimization of preoperative and intraoperative procedures. Eur J Endocrinol. 2003;149:7-15.
22. Norman J, Denham D. Minimally invasive radioguided parathyroidectomy in the reoperative neck. Surgery. 1998;124:1088-1092.
23. Flynn MB, Bumpouns JM, Schill K, McMasters KM. Minimally invasive radioguided parathyroidectomy. J Am Coll Surg. 2000;191:24-31.
24. McGreal G, Winter DC, Sookhai S, et al. Minimally invasive, radioguided surgery for primary hyperparathyroidism. Ann Surg Oncol. 2001;8:856-860.
25. Perrier ND, Ituarte PHG, Morita E, et al. Parathyroid surgery: separating promise from reality. J Clin Endocrinol Metab. 2002;87:1024-1029.
26. Sfakianakis GN, Irvin GL, Foss J, et al. Efficient parathyroidectomy guided by SPECT-MIBI and hormonal measurements. J Nucl Med. 1996;37:798-804.
27. Moka D, Voth E, Dietlein M, Larena-Avellaneda A, Schicha H. Technetium 99m-MIBI-SPECT: a highly sensitive diagnostic tool for localization of parathyroid adenomas. Surgery. 2000;128:29-35.
28. Giordano A, Rubello D, Casara D. New trends in parathyroid scintigraphy. Eur J Nucl Med. 2001;28:1409-1420.
29. Bonjer HJ, Bruining HA, Pols HAP, et al. Intraoperative nuclear guidance in benign hyperparathyroidism and parathyroid cancer. Eur J Nucl Med. 1997;27: 246-251.
30. Duy OY. Presidential address: minimally invasive endocrine surgery-standard of treatment or hype? Surgery. 2003;134:849-857.
31. Murphy C, Norman J. The 20% rule: a simple, instantaneous radioactivity measurement defines cure and allows elimination of frozen sections and hormone assays during parathyroidectomy. Surgery. 1999;126:1023-1029.