Characterization of the asialoglycoprotein receptor under hypoxic conditions in primary cultured rat hepatocytes

Journal of Nuclear Medicine

Volumn 46, Issue 2, 2005, Pages 321-325

  Kwon, A Hon ^a   Inoue, Tomohisa ^a   Ha Kawa, Sang Kil ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Hepatocyte culture; Hepatology; Hypoxic injury; Ketone body ratio; Radiochemistry; Radiopharmaceuticals

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; GALACTOSE; HUMAN SERUM ALBUMIN; KETONE BODY; TECHNETIUM 99M; TECHNETIUM GALACTOSYL HUMAN SERUM ALBUMIN TC 99M; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; MACROSALB TC 99M; PENTETATE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT; TECHNETIUM TC 99M DTPA GALACTOSYL HUMAN SERUM ALBUMIN; TECHNETIUM TC 99M DTPA-GALACTOSYL-HUMAN SERUM ALBUMIN;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOCYTOSIS; HYPOXIA; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CELL HYPOXIA; METABOLIC CLEARANCE RATE; METABOLISM; PHYSIOLOGY; SCINTISCANNING; WISTAR RAT;

ANIMALS; ASIALOGLYCOPROTEIN RECEPTOR; CELL HYPOXIA; CELLS, CULTURED; ENDOCYTOSIS; HEPATOCYTES; MALE; METABOLIC CLEARANCE RATE; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TECHNETIUM TC 99M PENTETATE;

EID: 15844376332     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Delva E, Camus Y, Nordlinger B, et al. Vascular occlusions for liver resections: operative management and tolerance to hepatic ischemia: 142 cases. Ann Surg. 1989;209:211-218.
2. Clavien PA, Harvey PR, Strasberg SM. Preservation and reperfusion injuries in liver allografts: an overview and synthesis of current studies. Transplantation. 1992;53:957-978.
3. Sawamura T, Kawasato S, Shiozaki Y, Sameshima Y, Nakada H, Tashiro Y. Decrease of a hepatic binding protein specific for asialoglycoproteins with accumulation of serum asialoglycoproteins in galactosamine-treated rats. Gastroenterology. 1981;81:527-533.
4. Sawamura T, Nakada H, Hazama H, Shiozaki Y, Sameshima Y, Tashiro Y. Hyperasialoglycoproteinemia in patients with chronic liver diseases and/or liver cell carcinoma: asialoglycoprotein receptor in cirrhosis and liver cell carcinoma. Gastroenterology. 1984;87:1217-1221.
5. 99mTc-DTPA-asialo-orosomucoid. II: human dynamic and imaging studies. J Nucl Med Allied Sci. 1988;32:117-126.
6. Ha-Kawa SK, Tanaka Y. A quantitative model of technetium-99m-DTPA- galactosyl-HSA for the assessment of hepatic blood flow and hepatic binding receptor. J Nucl Med. 1991;32:2233-2240.
7. Iwata K, Shijo H, Kamimura S, et al. Effects of esophageal varices obliteration by endoscopic variceal sclerotherapy on asialoscintigraphy and liver function test. Hepatol Res. 2002;22:45-51.
8. Toyama H, Suzuki K, Naito A, et al. Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recovery. Ann Nucl Med. 1999;13:155-160.
9. 2 in primary culture of adult rat hepatocytes. J Biochem. 1984;96:429-436.
10. Kamiya T, Kwon AH, Kanemaki T, et al. A simplified model of hypoxic injury in primary cultured rat hepatocytes. In Vitro Cell Dev Biol Anim. 1998;34:131-137.
11. Rosenthal HE. A graphic method for the determination and presentation of binding parameters in a complex system. Anal Biochem. 1967;20:525-532.
12. Uno S, Ito S, Kurono M, Yamaoka Y, Kamiyama Y, Ozawa K. A simple and sensitive assay for blood ketone bodies using highly purified 3-hydroxybutyrate dehydrogenase. Clin Chim Acta. 1987;168:253-255.
13. McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med. 1985;312:159-163.
14. Cheung JY, Bonventre JV, Malis CD, Leaf A. Calcium and ischemic injury. N Engl J Med. 1986;314:1670-1676.
15. Marubayashi S, Dohi K, Ezaki H, Hayashi K, Kawasaki T. Preservation of ischemic rat liver mitochondrial functions and liver viability with CoQ10. Surgery. 1982;91:631-637.
16. Hayashi T, Nagasue N, Kohno H, Chang YC, Nakamura T. Beneficial effect of cyclosporine pretreatment in canine liver ischemia: enzymatic and electronmicroscopic studies. Transplantation. 1991;52:116-121.
17. Liu W, Schob O, Pugmire JE, et al. Glycohydrolases as markers of hepatic ischemia-reperfusion injury and recovery. Hepatology. 1996;24:157-162.
18. Wakabayashi H, Karasawa Y, Tanaka S, Kokudo Y, Maeba T. The effect of FK506 on warm ischemia and reperfusion injury in the rat liver. Surg Today. 1994;24:994-1002.
19. Burgess JB, Baenziger JU, Brown WR. Abnormal surface distribution of the human asialoglycoprotein receptor in cirrhosis. Hepatology. 1992;15:702-706.
20. Casey CA, Kragskow SL, Sorrell MF, Tuma DJ. Effect of chronic ethanol administration on total asialoglycoprotein receptor content and intracellular processing of asialoorosomucoid in isolated rat hepatocytes. Biochim Biophys Acta. 1990;1052:1-8.
21. Goldstein JL, Brown MS, Anderson RG, Russell DW, Schneider WJ. Receptor-mediated endocytosis: concepts emerging from the LDL receptor system. Annu Rev Cell Biol 1985;1:1-39.
22. Grant DA, Kaderbhai N. A reassessment of the assay for the asialoglycoprotein receptor and its use in the quantification of receptor distribution in hepatocytes. Biochem J. 1986;234:131-137.
23. Weigel PH. Characterization of the asialoglycoprotein receptor on isolated rat hepatocytes. J Biol Chem. 1980;255:6111-6120.
24. Harada M, Sakisaka S, Yoshitake M, et al. Role of cytoskeleton and acidification of endocytic compartment in asialoglycoprotein metabolism in isolated rat hepatocyte couplets. Hepatology. 1995;21:1413-1421.
25. Mon K, Ozawa K, Yamamoto Y, et al. Response of hepatic mitochondrial redox state to oral glucose load: redox tolerance test as a new predictor of surgical risk in hepatectomy. Ann Surg. 1990;211:438-446.
26. Veech RL, Raijman L, Krebs HA. Equilibrium relations between the cytoplasmic adenine nucleotide system and nicotinamide-adenine nucleotide system in rat liver. Biochem J. 1970;117:499-503.
27. Tanaka J, Ozawa K, Tobe T. Significance of blood ketone body ratio as an indicator of hepatic cellular energy status in jaundiced rabbits. Gastroenterology. 1979;76:691-696.
28. Ukikusa M, Ozawa K, Shimahara Y, Asano M, Nakatani T, Tobe T. Changes in blood ketone body ratio: their significance after major hepatic resection. Arch Surg. 1981;116:781-785.
29. Yamamoto M, Tanaka J, Ozawa K, Tobe T. Significance of acetoacetate/β-hydroxybutyrate ratio in arterial blood as an indicator of the severity of hemorrhagic shock. J Surg Res. 1980;28:124-131.
30. Orrenius S, Thor H, Rajs J, Berggren M. Isolated rat hepatocytes as an experimental tool in the study of cell injury: effect of anoxia. Forensic Sci. 1976;8: 255-263.
31. Karwinski W, Farstad M, Ulvik R, Soreide O. Sixty-minute normothermic liver ischemia in rats: evidence that allopurinol improves liver cell energy metabolism during reperfusion but that timing of drug administration is important. Transplantation. 1991;52:231-234.
32. Vibulsreth S, Hefti F, Ginsberg MD, Dietrich WD, Busto R. Astrocytes protect cultured neurons from degeneration induced by anoxia. Brain Res. 1987;422:303-311.