Messenger RNA transcripts of the meiotic regulator BOULE in the testis of azoospermic men and their application in predicting the success of sperm retrieval

Human Reproduction

Volumn 20, Issue 3, 2005, Pages 782-788

  Lin, Yung Ming ^a   Kuo, Pao Lin ^a   Lin, Ying Jung ^a   Teng, Yen Ni ^b   Lin, Johnny Shinn Nan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Azoospermia; BOULE; Testis

Indexed keywords

GENE PRODUCT; MESSENGER RNA; PROTEIN BOULE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AZOOSPERMIA; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DISEASE SEVERITY; HORMONE BLOOD LEVEL; HUMAN; MALE; MEIOSIS; PHENOTYPE; PREDICTION; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SEMEN ANALYSIS; SENSITIVITY AND SPECIFICITY; SPERMATOZOON ABNORMALITY; STATISTICAL SIGNIFICANCE; TESTICULAR SPERM EXTRACTION; TRANSCRIPTION REGULATION;

EID: 15844375874     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deh647     Document Type: Article

References (16)

1. Castrillon DH, Gonczy P, Alexander S, Rawson R, Eberhart CG, Viswanathan S, Di Nardo S and Wasserman SA (1993) Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135,489-505.
2. Courtot C, Fankhauser C, Simanis V and Lehner CF (1992) The Drosophila cdc25 homologue twine is required for meiosis. Development 116, 405-416.
3. Devroey P, Liu J, Nagy Z, Goossens A, Tournaye H, Camus M, Van Steirteghem A and Silber S (1995) Pregnancies after testicular sperm extraction and intracytoplasmic sperm injection (ICSI) in non-obstructive azoospermia. Hum Reprod 10,1457-1460.
4. Eberhart CG, Maines JZ and Wasserman SA (1996) Meiotic cell cycle requirement for a fly homologue of human Deleted in AZoospermia. Nature 381,783-785.
5. Kuo PL, Lin YH, Teng YN, Hsu CC, Lin JSN and Lin YM (2004) Transcriptional levels of four Y chromosome-linked AZF genes in azoospermic men and their association with successful sperm retrieval. Urology 63, 131-136.
6. Luetjens CM, Xu EY, Reijo RA, Kamischke A, Nieschlag E and Gromoll J (2004) Association of meiotic arrest with lack of BOULE protein expression in infertile men. J Clin Endocrinol Metab 89, 1926-1933.
7. Maines JZ and Wasserman SA (1999) Post-transcriptional regulation of the meiotic Cdc25 protein Twine by the Dazl orthologue Boule. Nat Cell Biol 1,171-174.
8. Seo JT and Ko WJ (2001) Predictive factors of successful testicular sperm recovery in non-obstructive azoospermia patients. Int J Androl 24, 306-310.
9. Silber SJ, Van Steirteghem AC and Devroey P (1995) Sertoli cell only revisited. Hum Reprod 10,1031-1032.
10. Silber SJ, Van Steirteghem A, Nagy Z, Liu J, Tournaye H and Devroey P (1996) Normal pregnancies resulting from testicular sperm extraction and intracytoplasmic sperm injection for azoospermia due to maturation arrest. Fertil Steril 66,110-117.
11. Silber SJ, Nagy Z, Devroey P, Tournaye H and Van Steirteghem AC (1997) Distribution of spermatogenesis in the testicles of azoospermic men: the presence or absence of spermatids in the testes of men with germinal failure. Hum Reprod 12,2422-2428.
12. Su LM, Palermo GD, Goldstein M, Veeck LL, Rosenwaks Z and Schlegel PN (1999) Testicular sperm extraction with intracytoplasmic sperm injection for nonobstructive azoospermia: testicular histology can predict success of sperm retrieval. J Urol 161,112-116.
13. Tournaye H, Verheyen G, Nagy Z, Ubaldi F, Goossens A, Silber S, Van Steirteghem AC and Devroey P (1997) Are there any predictive factors for successful testicular sperm recovery in azoospermic patients? Hum Reprod 12,80-86.
14. Tsai SJ and Wiltbank MC (1996) Quantification of mRNA using competitive RT-PCR with standard-curve methodology. Biotechniques 21, 862-866.
15. Xu EY, Lee DF, Klebes A, Turek PJ, Komberg TB and Reijo RA (2003) Human BOULE gene rescues meiotic defects in infertile flies. Hum Mol Genet 12,169-175.
16. Xu EY, Moore FL and Reijo RA (2001) A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans. Proc Natl Acad Sci USA 98,7414-7419.