A synthetic peptide forms voltage-gated porin-like ion channels in lipid bilayer membranes

Biochemical and Biophysical Research Communications

Volumn 330, Issue 2, 2005, Pages 585-590

  Thundimadathil, Jyothi ^a   Roeske, Roger W ^a   Guo, Lili ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Conformation; Planar lipid bilayer membrane; Porins; Synthetic peptides; Voltage gated channels; barrel structure

Indexed keywords

AMINO ACID DERIVATIVE; BACTERIAL TOXIN; GLYCINE DERIVATIVE; ION CHANNEL; PEPTIDE DERIVATIVE; PORIN; UNCLASSIFIED DRUG; VALYLSERYLLEUCYLGLYCYLLEUCYLSERYLISOLEUCYLGLYCYLPHENYLALANYLSERYLVALYL GLYCYLVALYLSERYLISOLEUCYLGLYCYLTRYPTOPHYLSERYLPHENYLALANYLGLYCYLARGINYLSERYL ARGINYLGLYCINE;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; CHANNEL GATING; COMPLEX FORMATION; CORRELATION ANALYSIS; ION TRANSPORT; LIPID BILAYER; MEMBRANE CHANNEL; MEMBRANE CONDUCTANCE; MEMBRANE POTENTIAL; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; STRUCTURE ANALYSIS;

EID: 15744405292     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.02.184     Document Type: Article

References (23)

1. G. Bainbridge, I. Gokce, and J.H. Lakey Voltage gating is a fundamental feature of porin and toxin β barrel membrane channels FEBS Lett. 431 1998 305 308
2. R. Benz, A. Schmid, and R.W. Hancock Ion selectivity of gram-negative bacterial porins J. Bacteriol. 153 1983 241 252
3. G.E. Schulz Porins: general to specific, native to engineered passive pores Curr. Opin. Struct. Biol. 6 1996 485 490
4. K. Hill, K. Model, M.T. Ryan, K. Dietmeier, F. Martin, R. Wagner, and N. Pfanner Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins Nature 395 1998 516 521
5. E. Schleiff, J. Soll, M. Kuchler, W. Kuhlbrandt, and R. Harrer Characterization of the translocon of the outer envelope of choloroplasts J. Cell Biol. 160 2003 541 551
6. A.P. Heuck, R.K. Tweten, and A.E. Johnson β-Barrel pore forming toxins: intriguing dimorphic proteins Biochemistry 40 2001 9065 9073
7. T. Chakraborthy, A. Schmid, S. Notermans, and R. Benz Aerolysin of Aeromonas sorbia: evidence for formation of ion permeable channels and comparison with alpha-toxin of Staphylococcus aureus Infect. Immun. 58 1990 2127 2132
8. F. Kovacs, J. Quine, and T.A. Cross Validation of the single-stranded channel conformation of gramicidin A by solid-state NMR Proc. Natl. Acad. Sci. USA 96 1999 7910 7915
9. S.J. Kennedy Structures of membrane proteins J. Membr. Biol. 42 1978 265 279
10. S.J. Kennedy, R.W. Roeske, A.R. Freeman, A.M. Watanabe, and H.R. Besch Jr. Synthetic peptides form ion channels in artificial lipid bilayer membranes Science 196 1977 1341 1342
11. F. Heitz, and G. Spach Ionic channels of some glycine-rich synthetic polyopeptides Biochem. Biophys. Res. Commun. 105 1982 179 185
12. Y. Mandel-Gutfreund, and L.M. Gregoret On the significance of alternating patterns of polar and non-polar residues in beta-strands J. Mol. Biol. 323 2002 453 461
13. R. Benz, K. Janko, W. Boos, and P. Lauger Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli Biochim. Biophys. Acta 511 1978 305 319
14. B.A. Wallace, and E.R. Blout Conformation of an oligopeptide in phospholipid vesicles Proc. Natl. Acad. Sci. USA 76 1979 1775 1779
15. C. Berrier, A. Coulombe, C. Houssin, and A. Ghazi Fast and slow kinetics of porin channels from Escherichia coli reconstituted into giant liposomes and studied by patch-clamp FEBS. Lett. 306 1992 251 256
16. Y.N. Chirgadze, O.V. Fedorov, and N.P. Trushima Estimation of amino acid residue side chain absorption in the infrared spectra of protein solutions in heavy water Biopolymers 14 1975 679 694
17. A. Barth, and C. Zscherp What vibrations tell us about proteins Q. Rev. Biophys. 35 2002 369 430
18. M. Jackson, and H.H. Mantsch The use and misuse of FTIR spectroscopy in the determination of protein structure Crit. Rev. Biochem. Mol. Biol. 30 1995 95 120
19. N. Sreerama, and R.W. Woody Computation and analysis of protein circular dichroism spectra Methods Enzymol. 38 2004 318 351
20. P.G. Bagos, T.D. Liakopoulos, I.C. Spyropoulos, and S.J. Hamodrakas PRED-TMBB: a web server for predicting the topology of β barrel outer membrane proteins Nucleic Acids Res. 32 2004 W400 W404
21. J.E. Gouaux, O. Braha, M.R. Hobaugh, L. Song, S. Cheley, C. Shustak, and H. Bayley Subunit stoichiometry of staphylococcal α-hemolysin in crystals and on membranes: a heptameric transmembrane pore Proc. Natl. Acd. Sci. USA 91 1994 12828
22. M.O. Chaney, S.D. Webster, Y. Kuo, and A.E. Roher Molecular modeling of the Abeta1-42 peptide from Alzheimer's disease Protein Eng. 11 1998 761 767
23. W.C. Wimley Toward genomic identification of β-barrel membrane proteins: composition and architecture of known structures Protein Sci. 11 2002 301 312