Retinoic acid and arsenic for treating acute promyelocytic leukemia

PLoS Medicine

Volumn 2, Issue , 2005, Pages 0033-0038

  Zhou, Guang Biao ^a   Zhao, Wei Li ^a   Wang, Zhen Yi ^a   Chen, Sai Juan ^a   Chen, Zhu ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ARSENIC; RETINOIC ACID; ANTINEOPLASTIC AGENT;

ACUTE GRANULOCYTIC LEUKEMIA; BLOOD CLOTTING DISORDER; BONE MARROW HYPOPLASIA; CANCER CHEMOTHERAPY; CLINICAL TRIAL; DRUG EFFECT; HUMAN; LEUKEMIA CELL; PROMYELOCYTE; PROMYELOCYTIC LEUKEMIA; REVIEW; SIDE EFFECT; DRUG COMBINATION;

ANTINEOPLASTIC AGENTS; ARSENIC; DRUG THERAPY, COMBINATION; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; TRETINOIN;

EID: 15744398524     PISSN: 15491277     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pmed.0020012     Document Type: Review

References (43)

1. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, et al. (1985) Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med 103: 620-625.
2. Chen Z, Wang ZY (2003) Acute promyelocytic leukemia. In: Pui CH, editor. Treatment of acute leukemias: New directions for clinical research. Towtowa (New Jersey): Humana Press. pp. 291-308.
3. Fibach E, Hayashi M, Sachs L (1973) Control of normal differentiation of myeloid leukemic cells to macrophages and granulocytes. Proc Natl Acad Sci U S A 70: 343-346.
4. Paran M, Sachs L, Barak Y, Resnitzky P (1970) In vitro induction of granulocyte differentiation in hematopoietic cells from leukemic and non-leukemic patients. Proc Natl Acad Sci U S A 67: 1542-1549.
5. Sachs L (1978) The differentiation of myeloid leukaemia cells: New possibilities for therapy. Br J Haematol 40: 509-517.
6. Breitman TR, Selonick SE, Collins SJ (1980) Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci U S A 77: 2936-2940.
7. Breitman TR, Collins SJ, Keene BR (1981) Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid. Blood 57: 1000-1004.
8. Flynn PJ, Miller WJ, Weisdorf DJ, Arthur DC, Brunning R, et al. (1983) Retinoic acid treatment of acute promyelocytic leukemia: In vitro and in vivo observations. Blood 62: 1211-1217.
9. Fontana JA, Rogers JS, Durham JP (1986) The role of 13 cis-retinoic acid in the remission induction of a patient with acute promyelocytic leukemia. Cancer 57: 209-217.
10. Nilsson B (1984) Probable in vivo induction of differentiation by retinoic acid of promyelocytes in acute promyelocytic leukaemia. Br J Haematol 57: 365-371.
11. Runde V, Aul C, Sudhoff T, Heyll A, Schneider W (1992) Retinoic acid in the treatment of acute promyelocytic leukemia: Inefficacy of the 13-cis isomer and induction of complete remission by the all-trans isomer complicated by thromboembolic events. Ann Hematol 64: 270-272.
12. Huang ME, Ye YC, Chen SR, Chai JR, Lu JX, et al. (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72: 567-572.
13. Wang ZY (2003) Ham-Wasserman lecture: Treatment of acute leukemia by inducing differentiation and apoptosis. Hematology (Am Soc Hematol Educ Program) 2003: 1-13.
14. Zhu J, Chen Z, Lallemand-Breitenbach V, de The H (2002) How acute promyelocytic leukaemia revived arsenic. Nat Rev Cancer 2: 705-713.
15. Zhang P, Wang SY, Hu LH (1995) Arsenic trioxide treated 72 cases of acute promyelocytic leukemia. Chin J Hematol 17: 58-62.
16. Sun HD, Ma L, Hu XC, Zhang TD (1992) Ai-Lin I treated 32 cases of acute promyelocytic leukemia. Chin J Integrat Chin West Med 12: 170-171.
17. Shen ZX, Chen GQ, Ni JH, Li XS, Xiong SM, et al. (1997) Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 89: 3354-3360.
18. Lu DP, Qiu JY, Jiang B, Wang Q, Liu KY, et al. (2002) Tetra-arsenic tetra-sulfide for the treatment of acute promyelocytic leukemia: A pilot report. Blood 99: 3136-3143.
19. Chen GQ, Shi XG, Tang W, Xiong SM, Zhu J, et al. (1997) Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dosedependent dual effects on APL cells. Blood 89: 3345-3353.
20. Melnick A, Licht JD (1999) Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93: 3167-3215.
21. de The H, Chomienne C, Lanotte M, Degos L, Dejean A (1990) The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus. Nature 347: 558-561.
22. Kakizuka A, Miller WH Jr, Umesono K, Warrell RP Jr, Frankel SR, et al. (1991) Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66: 663-674.
23. Shih LY, Kuo MC, Liang DC, Huang CF, Lin TL, et al. (2003) Internal tandem duplication and Asp835 mutations of the FMS-like tyrosine kinase 3 (FLT3) gene in acute promyelocytic leukemia. Cancer 98: 1206-1216.
24. Nervi C, Ferrara FF, Fanelli M, Rippo MR, Tomassini B, et al. (1998) Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein. Blood 92: 2244-2251.
25. Zhu J, Gianni M, Kopf E, Honore N, Chelbi-Alix M, et al. (1999) Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins. Proc Natl Acad Sci U S A 96: 14807-14812.
26. vom Baur E, Zechel C, Heery D, Heine MJ, Garnier JM, et al. (1996) Differential liganddependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J 15: 110-124.
27. Lallemand-Breitenbach V, Zhu J, Puvion F, Koken M, Honore N, et al. (2001) Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation. J Exp Med 193: 1361-1371.
28. Muller S, Matunis MJ, Dejean A (1998) Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J 17: 61-70.
29. Kamashev D, Vitoux D, de The H (2004) PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute promyelocytic leukemia cell differentiation. J Exp Med 199: 1163-1174.
30. Liu TX, Zhang JW, Tao J, Zhang RB, Zhang QH, et al. (2000) Gene expression networks underlying retinoic acid-induced differentiation of acute promyelocytic leukemia cells. Blood 96: 1496-1504.
31. Rocca B, Morosetti R, Habib A, Maggiano N, Zassadowski F, et al. (2004) Cyclooxygenase-1, but not -2, is upregulated in NB4 leukemic cells and human primary promyelocytic blasts during differentiation. Leukemia 18: 1373-1379.
32. Kini AR, Peterson LA, Tallman MS, Lingen MW (2001) Angiogenesis in acute promyelocytic leukemia: Induction by vascular endothelial growth factor and inhibition by alltrans retinoic acid. Blood 97: 3919-3924.
33. Zhu J, Guo WM, Yao YY, Zhao WL, Pan L, et al. (1999) Tissue factors on acute promyelocytic leukemia and endothelial cells are differently regulated by retinoic acid, arsenic trioxide and chemotherapeutic agents. Leukemia 13: 1062-1070.
34. Jing Y, Wang L, Xia L, Chen GQ, Chen Z, et al. (2001) Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. Blood 97: 264-269.
35. Lallemand-Breitenbach V, Guillemin MC, Janin A, Daniel MT, Degos L, et al. (1999) Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J Exp Med 189: 1043-1052.
36. Shen ZX, Shi ZZ, Fang J, Gu BW, Li JM, et al. (2004) All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A 101: 5328-5335.
37. Bourgeois E, Chevret S, Sanz M, Dombret H, Thomas X, et al (2003) Long term follow up of APL treated with ATRA and chemotherapy (CT) including incidence of late relapses and overall toxicity [abstract]. Blood 102 (11): Abstract 483.
38. Iland H, Bradstock K, Chong L, Springall F, Ayling J, et al (2003) Results of the APML3 Trial of ATRA, intensive idarubicin, and triple maintenance combined with molecular monitoring in acute promyelocytic leukemia (APL): A study by the Australasian leukemia and lymphoma Group (ALLG) [abstract]. Blood 102: Abstract 484.
39. Testi AM, Lo Coco F, Biondi A, Moleti ML, Giona F, et al (2003) GIMEMA-AIEOP AIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children [abstract]. Blood 102: Abstract 485.
40. Avvisati G, Petti MC, Lo Coco F, Testi AM, Fazi P, et al (2003) AIDA: The Italian way of treating acute promyelocytic leukemia (APL), final act [abstract]. Blood 102: Abstract 487.
41. Ortega JJ, Martin G, Madero L, Deben G, Molines A, et al (2003) Treatment with all-trans retinoic acid and anthracycline monochemotherapy in children with acute promyelocytic leukemia: A multicenter study by the PETHEMA group [abstract]. Blood 102: Abstract 2285.
42. Ades L, Chevret S, de Botton S, Thomas X, Dombret H, et al (2003) Outcome of acute promyelocytic leukemia (APL) treated with all trans retinoic acid (ATRA) and chemotherapy (CT) in elderly patients (>60 years): The European group experience [abstract]. Blood 102: Abstract 2286
43. Mandelli F, Latagliata R, Avvisati G, Fazi P, Rodeghiero F, et al (2003) Treatment of elderly patients (> or =60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols. Leukemia 17: 1085-1090.