Undifferentiated large cell carcinoma of the thymus associated with castleman disease-like reaction: A distinctive type of thymic neoplasm characterized by an indolent behavior

American Journal of Surgical Pathology

Volumn 29, Issue 4, 2005, Pages 490-495

  Nonaka, Daisuke ^a,c   Rodriguez, Jaime ^a   Rollo, John L ^b   Rosai, Juan ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b Jefferson Memorial Hospital   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Castleman disease; Follicular dendritic cell sarcoma; Thymic carcinoma

Indexed keywords

CD68 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; CYTOKERATIN; EPIDERMAL GROWTH FACTOR RECEPTOR;

ACANTHOSIS NIGRICANS; ADULT; ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DENDRITIC CELL; DISEASE ASSOCIATION; DISEASE COURSE; DYSPNEA; FATIGUE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; INCIDENTAL FINDING; INFLAMMATION; LARGE CELL CARCINOMA; LYMPH NODE METASTASIS; MALE; POSITRON EMISSION TOMOGRAPHY; RETICULUM CELL; THORAX PAIN; THYMUS CANCER; UNDIFFERENTIATED CARCINOMA; WEIGHT REDUCTION;

CARCINOMA, LARGE CELL; DISEASE-FREE SURVIVAL; FEMALE; GIANT LYMPH NODE HYPERPLASIA; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIOGRAPHY, THORACIC; RADIOTHERAPY, ADJUVANT; THYMECTOMY; THYMUS NEOPLASMS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 15744396572     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000155148.45423.b5     Document Type: Article

References (31)

1. Castleman B, Iverson L, Menendez VP. Localized mediastinal lymph node hyperplasia resembling thymoma. Cancer. 1956;9:822-830.
2. Castleman B. Case records of the Massachusetts General Hospital: case no. 40011. N Engl J Med. 1954;250:26-30.
3. Cesarman E, Knowles DM. Kaposi's sarcoma-associated herpesvirus: a lymphotropic human herpesvirus associated with Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Semin Diagn Pathol. 1997;14:54-66.
4. Chan AC, Chan KW, Chan JK, et al. Development of follicular dendritic cell sarcoma in hyaline-vascular Castleman's disease of the nasopharynx: tracing its evolution by sequential biopsies. Histopathology. 2001;38:510-518.
5. Chan JK, Tsang WY, Ng CS. Follicular dendritic cell tumor and vascular neoplasm complicating hyaline-vascular Castleman's disease. Am J Surg Pathol. 1994;18:517-525.
6. Choi WW, Lui YH, Lau WH, et al. Adenocarcinoma of the thymus: report of two cases, including a previously undescribed mucinous subtype. Am J Surg Pathol. 2003;27:124-130.
7. Cingolani N, Shaco-Levy R, Farruggio A, et al. Alpha-fetoprotein production by pancreatic tumors exhibiting acinar cell differentiation: study of five cases, one arising in a mediastinal teratoma. Hum Pathol. 2000;31:938-944.
8. Danon AD, Krishnan J, Frizzera G. Morpho-immunophenotypic diversity of Castleman's disease, hyaline-vascular type: with emphasis on a stroma-rich variant and a new pathogenetic hypothesis. Virchows Arch A Pathol Anal Histopathol. 1993;423:369-382.
9. Dargent JL, Delplace J, Roufosse C, et al. Development of a calcifying fibrous pseudotumour within a lesion of Castleman's disease, hyaline-vascular subtype. J Clin Pathol. 1999;52:547-549.
10. Franke A, Strobel P, Fackeldey V, et al. Hepatoid thymic carcinoma: report of a case. Am J Surg Pathol. 2004;28:250-256.
11. Frizzera G, Banks PM, Massarelli G, et al. A systemic lymphoproliferative disorder with morphologic features of Castleman's disease: pathological findings in 15 patients. Am J Surg Pathol. 1983;7:211-231.
12. Frizzera G. Castleman's disease: more questions than answers. Hum Pathol. 1985;16:202-205.
13. Frizzera G. Castleman's disease and related disorders. Semin Diagn Pathol. 1988;5:346-364.
14. Gerald W, Kostianovsky M, Rosai J. Development of vascular neoplasia in Castleman's disease: report of seven cases. Am J Surg Pathol. 1990;14:603-614.
15. Izumi M, Mochizuki M, Kuroda M, et al. Angiomyoid proliferative lesion: an unusual stroma-rich variant of Castleman's disease of hyaline-vascular type. Virchows Arch. 2002;441:400-405.
16. Karcher DS, Pearson CE, Butler WM, et al. Giant lymph node hyperplasia involving the thymus with associated nephrotic syndrome and myelofibrosis. Am J Clin Pathol. 1982;77:100-104.
17. Keller AR, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer. 1972;29:670-683.
18. Lin O, Frizzera G. Angiomyoid and follicular dendritic cell proliferative lesions in Castleman's disease of hyaline-vascular type: a study of 10 cases. Am J Surg Pathol. 1997;21:1295-1306.
19. Middleton G. Involvement of the thymus by metastatic neoplasms. Br J Cancer. 1966;20:41-46.
20. Nishimoto N, Sasai M, Shima Y, et al. Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. Blood. 2000;95:56-61.
21. O'Reilly PE Jr, Joshi VV, Holbrook CT, et al. Multicentric Castleman's disease in a child with prominent thymic involvement: a case report and brief review of the literature. Mod Pathol. 1993;6:776-780.
22. Pauwels P, Dal Cin P, Vlasveld LT, et al. A chromosomal abnormality in hyaline vascular Castleman's disease: evidence for clonal proliferation of dysplastic stromal cells. Am J Surg Pathol. 2000;24:882-888.
23. Ritter JH, Wick MR. Primary carcinomas of the thymus gland. Semin Diagn Pathol. 1999;16:18-31.
24. Rosai J. Histological Typing of Tumours of the Thymus. Berlin: Springer-Verlag, 1999.
25. Ruco LP, Gearing AJ, Pigott R, et al. Expression of ICAM-1, VCAM-1 and ELAM-1 in angiofollicular lymph node hyperplasia (Castleman's disease): evidence for dysplasia of follicular dendritic reticulum cells. Histopathology. 1991;19:523-528.
26. Shimosato Y, Mukai K. Tumors of the mediastinum. In: Atlas of Tumor Pathology, 3rd series, fascicle 21. Washington, DC: Armed Forces Institute of Pathology, 1997:120-158.
27. Soulier J, Grollet L, Oksenhendler E, et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood. 1995;86:1276-1280.
28. Sun X, Chang KC, Abruzzo LV, et al. Epidermal growth factor receptor expression in follicular dendritic cells: a shared feature of follicular dendritic cell sarcoma and Castleman's disease. Hum Pathol. 2003;34:835-840.
29. Suster S, Rosai J. Thymic carcinoma: a clinicopathologic study of 60 cases. Cancer. 1991;67:1025-1032.
30. Wick MR, Swanson PE, Manivel JC. Placental-like alkaline phosphatase reactivity in human tumors: an immunohistochemical study of 520 cases. Hum Pathol. 1987;18:946-954.
31. Zarate-Osorno A, Medeiros LJ, Danon AD, et al. Hodgkin's disease with coexistent Castleman-like histologie features: a report of three cases. Arch Pathol Lab Med. 1994;118:270-274.