Tetrahydroaminoacridine, a cholinesterase inhibitor, and D-cycloserine, a partial NMDA receptor-associated glycine site agonist, enhances acquisition of spatial navigation

NeuroReport

Volumn 9, Issue 7, 1998, Pages 1633-1637

  Riekkinen Jr , Paavo ^a   Ikonen, Sami ^a   Riekkinen, Minna ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Alzheimer's disease; Combined therapy; D cycloserine; Passive avoidance; THA; Water maze

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CYCLOSERINE; GLYCINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TACRINE; WATER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; SWIMMING;

EID: 15644371818     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199805110-00068     Document Type: Article

References (15)

1. Bierer LM, Haroutunian V, Gabriel S et al. J Neurochem 64, 749-760 (1995).
2. Francis PT, Cross AJ and Bowen DM. Neurotransmitters and neuropeptides. In: Terry RD, Katzman R and Bick KL, eds. Alzheimer Disease, 247-261 (1994).
3. Knapp MJ, Knopman DS, Solomon PR et al. JAMA 271, 985-991 (1994).
4. Solomon PR, Knapp MJ, Gracon SI et al. Lancet 348, 275-276 (1996).
5. Braak H and Braak E. Acta Neurol Scand Suppl 165, 3-12 (1996).
6. Collingridge G and Singer W. Trends Pharmacol Sci 11, 290-296 (1990).
7. Hirotsu I, Hori N, Katsuda N et al. Brain Res 482, 194-197 (1989).
8. Aigner TG. Curr Opin Neurobiol 5, 155-160 (1995).
9. Sirvio J, Ekonsalo T, Riekkinen P Jr et al. Neurosci Lett 146, 215-218 (1992).
10. Riekkinen P Jr, Sivio J and Riekkinen P. Pharmacol Biochem Behav 36, 237-241 (1990).
11. Flood JF, Morley JE, Lanthorn TH. Eur J Pharmacol 221, 249-254 (1992).
12. Riekkinen et al 1990b
13. Hagan JJ and Morris RGM. The cholinergic hypothesis of memory: a review of animal experiments. In: Iversen LL and Iversen DS, eds. Handbook of Psychopharmacology, 237-323 (1989).
14. Staubli U and Lunch G. NMDA receptors and memory: evidence from pharmacological and correlational studies. In: Neurobiology of the NMDA Receptors New York: VCH Publishers, 1991: 129-148.
15. Searle clinical research report. Report No. NC6-93-06-09, September 29, Skokie IL, GD Searle (1993).