N-{trans-2-[[2'-(acetylamino)cyclohexyl]oxy]acetyl}-L-alanyl-D- glutamic acid: A novel immunologically active carbocyclic muramyl dipeptide analogue

Journal of Medicinal Chemistry

Volumn 41, Issue 4, 1998, Pages 530-539

  Kikelj, Danijel ^a   Pečar, Slavko ^a   Kotnik, Vladimir ^c   Štalc, Anton ^b   Wraber Herzog, Branka ^c   Simčič, Saša ^c   Ihan, Alojz ^c   Klamfer, Lidija ^c   Povšič, Lučka ^b   Grahek, Rok ^b   Suhadolc, Elizabeta ^a   Hočevar, Mirjam ^a   Hönig, Helmut ^d   Rogi Kohlenprath, Renate ^d  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b Lek dd   (Slovenia)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

^d GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE DERIVATIVE; CYCLOPHOSPHAMIDE; GLUTAMIC ACID DERIVATIVE; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; MURAMYL DIPEPTIDE DERIVATIVE; N [2 [[2' (ACETYLAMINO)CYCLOHEXYL]OXY]ACETYL] ALANYL DEXTRO GLUTAMIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE ACTIVATION; BLAST TRANSFORMATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; IMMUNOMODULATION; INFECTION PREVENTION; INFECTION RESISTANCE; MACROPHAGE ACTIVATION; MOUSE; MYCOSIS; NONHUMAN; T LYMPHOCYTE ACTIVATION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; B-LYMPHOCYTES; CYCLOPHOSPHAMIDE; FEMALE; IMMUNE TOLERANCE; IMMUNOSUPPRESSIVE AGENTS; INDICATORS AND REAGENTS; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED STRAINS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PLASMA CELLS; SPLEEN; STEREOISOMERISM; T-LYMPHOCYTES;

EID: 15644363079     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970509d     Document Type: Article

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