Mechanism of macrophage activation by chitin derivatives

Journal of Veterinary Medical Science

Volumn 67, Issue 1, 2005, Pages 51-56

  Mori, Takashi ^a   Murakami, Masaaki ^b   Okumura, Masahiro ^a   Kadosawa, Tsuyoshi ^a   Uede, Toshimitsu ^b   Fujinaga, Toru ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Chitosan; Macrophage activation; Mannose receptor; Wound healing

Indexed keywords

BIOLOGICAL MARKER; CELL SURFACE RECEPTOR; CHITIN; CHITOSAN; LAMINARAN; LECTIN; MANNAN; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; POLYSACCHARIDE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; DRUG EFFECT; MACROPHAGE ACTIVATION; METABOLISM; MOUSE; MOUSE STRAIN; PERITONEUM MACROPHAGE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELLS, CULTURED; CHITIN; CHITOSAN; LECTINS, C-TYPE; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MANNANS; MANNOSE-BINDING LECTINS; MICE; MICE, INBRED STRAINS; POLYSACCHARIDES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 15544362099     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.67.51     Document Type: Article

References (19)

1. Ashany, D., Song, X., Lacy, E., Nikolic-Zugic, J., Friedman, S. M. and Elkon, K. B. 1995. Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway. Proc. Natl. Acad. Sci. U. S. A. 92: 11225-11229.
2. Biagini, G., Bertani, A., Muzzarelli, R., Damadei, A., DiBenedetto, G., Belligolli, A., Riccotti, G., Zucchini, C. and Rizzoli, C. 1991. Wound management with N-carboxybutyl chitosan. Biomaterials 12: 281-286.
3. Car, B. D., Eng, V. M., Schnyder, B., Ozmen, L., Huang, S., Gallay, P., Heumann, D., Aguet, M. and Ryffel, B. 1994. Interferon gamma receptor deficient mice are resistant to endotoxic shock. J. Exp. Med. 179: 1437-1444.
4. Cerami, A. 1992. Inflammatory cytokines. Clin. Immunol. Immunopathol. 62: S3-10.
5. Chandy, T. and Sharma, C. P. 1990. Chitosan - as a biomaterial. Biomater. Artif. Cells Artif. Organs 18: 1-24.
6. Debono, M. and Gordee, R. S. 1994. Antibiotics that inhibit fungal cell wall development. Annu. Rev. Microbiol. 48: 471-497.
7. Di Pietro, L. A. 1995. Wound healing: the role of the macrophage and other immune cells. Shock 4: 233-240.
8. Driscoll, K. E., Hassenbein, D. G., Howard, B. W., Isfort, R. J., Cody, D., Tindal, M. H., Suchanek, M. and Carter, J. M. 1995. Cloning, expression, and functional characterization of rat MIP-2: a neutrophil chemoattractant and epithelial cell mitogen. J. Leukoc. Biol. 58: 359-364.
9. Leibovich, S. J. and Ross, R. 1975. The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum. Am. J. Pathol. 78: 71-100.
10. Marodi, L., Schreiber, S., Anderson, D. C., MacDermott, R. P., Korchak, H. M. and Johnston, R. B. Jr. 1993. Enhancement of macrophage candidacidal activity by interferon-gamma. Increased phagocytosis, killing, and calcium signal mediated by a decreased number of mannose receptors. J. Clin. Invest. 91: 2596-2601.
11. Minami, S., Okamoto, Y., Tanioka, S., Sashiwa, H., Saimoto, H., Matsuhashi, A. and Shigemasa, Y. 1993. Effects of chitosan on wound healing. pp. 141-152. In: Carbohydrates and Carbohydrate Polymer (Yalpani, M. ed.), ATL Press, IL.
12. Muzzarelli, R., Baldassarre, V., Conti, F., Ferrara, P., Biagini, G., Gazzanelli, G. and Vasi, V. 1988. Biological activity of chitosan: ultrastructural study. Biomaterials 9: 247-252.
13. Muzzarelli, R., Tarsi, R., Filippini, O., Giovanetti, E., Biagini, G. and Varaldo, P. E. 1990. Antimicrobial properties of N-carboxybutyl chitosan. Antimicrob. Agents Chemother. 34: 2019-2023.
14. Nishimura, K., Ishihara, C., Ukei, S., Tokura, S. and Azuma, I. 1986. Stimulation of cytokine production in mice using deacetylated chitin. Vaccine 4: 151-156.
15. Otterlei, M., Varum, K. M., Ryan, L. and Espevik, T. 1994. Characterization of binding and TNF-alpha-inducing ability of chitosans on monocytes: the involvement of CD14. Vaccine 12: 825-832.
16. Pangburn, S. H., Trescony, P. V. and Heller, J. 1982. Lysozyme degradation of partially deacetylated chitin, its films and hydrogels. Biomaterials 3: 105-108.
17. Peluso, G., Petillo, O., Ranieri, M., Santin, M., Ambrosio, L., Calabro, D., Avallone, B. and Balsamo, G. 1994. Chitosan-mediated stimulation of macrophage function. Biomaterials 15: 1215-1220.
18. Reed, J. C. 1994. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124: 1-6.
19. Yomota, C., Komuro, T. and Kimura, T. 1990. Studies on the degradation of chitosan films by lysozyme and release of loaded chemicals. Yakugaku Zasshi 110: 442-448 (in Japanese with English abstract).