메뉴 건너뛰기




Volumn 89, Issue 4, 1998, Pages 436-444

Epitope blocking: Positive and negative effects on the biodistribution of 125I-Labeled anti-tac disulfide-stabilized Fv fragment of two antibodies against different epitopes of the circulating antigen

Author keywords

Epitope; Fv fragment; Iodine 125; Monoclonal antibody; Radioimmunodetection

Indexed keywords

DISULFIDE; EPITOPE; IMMUNOGLOBULIN G; INTERLEUKIN 2 RECEPTOR; IODINE 125; MONOCLONAL ANTIBODY; RECEPTOR SUBUNIT;

EID: 15444358532     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb00582.x     Document Type: Article
Times cited : (3)

References (51)
  • 2
    • 0025174627 scopus 로고
    • Clinical radioimmunodetection, 1978-1988: Overview and suggestions for standardization of clinical trials
    • Larson, S. M. Clinical radioimmunodetection, 1978-1988: overview and suggestions for standardization of clinical trials. Cancer Res., 50, 892s-898s (1990).
    • (1990) Cancer Res. , vol.50
    • Larson, S.M.1
  • 3
    • 0026648277 scopus 로고
    • Radioimmunodetection in cancer identification
    • Goldenberg, D. M. and Larson, S. M. Radioimmunodetection in cancer identification. J. Nucl. Med., 33, 803-814 (1992).
    • (1992) J. Nucl. Med. , vol.33 , pp. 803-814
    • Goldenberg, D.M.1    Larson, S.M.2
  • 4
    • 0003182985 scopus 로고    scopus 로고
    • Radioimmunotherapy of leukemia and lymphoma
    • ed. H. Wagner. W.B. Saunders and Co., Philadelphia
    • Carrasquillo, J. A. Radioimmunotherapy of leukemia and lymphoma. In "Principles of Nuclear Medicine." 2nd Ed., ed. H. Wagner, pp. 1117-1132 (1996). W.B. Saunders and Co., Philadelphia.
    • (1996) "Principles of Nuclear Medicine." 2nd Ed. , pp. 1117-1132
    • Carrasquillo, J.A.1
  • 5
    • 0028939731 scopus 로고
    • Circulating antigen: Bad or good for immunoscintigraphy?
    • Pimm, M. V. Circulating antigen: bad or good for immunoscintigraphy? Nucl. Med. Biol., 22, 137-145 (1995).
    • (1995) Nucl. Med. Biol. , vol.22 , pp. 137-145
    • Pimm, M.V.1
  • 6
    • 0021970347 scopus 로고
    • Pharmacokinetic study of radiolabeled anti-colorectal carcinoma monoclonal antibodies in tumor-bearing nude mice
    • Douillard, J. Y., Chatal, J. F., Saccavini, J. C., Curtet, C., Kremer, M., Peuvrel, P. and Koprowski, H. Pharmacokinetic study of radiolabeled anti-colorectal carcinoma monoclonal antibodies in tumor-bearing nude mice. Eur. J. Nucl. Med., 11, 107-113 (1985).
    • (1985) Eur. J. Nucl. Med. , vol.11 , pp. 107-113
    • Douillard, J.Y.1    Chatal, J.F.2    Saccavini, J.C.3    Curtet, C.4    Kremer, M.5    Peuvrel, P.6    Koprowski, H.7
  • 7
    • 0025811926 scopus 로고
    • 111I-labelled F(ab′)2 fragments of human prostatic acid phosphatase monoclonal antibody in nude mice bearing PC-82 human prostatic tumour xenografts
    • 111I-labelled F(ab′)2 fragments of human prostatic acid phosphatase monoclonal antibody in nude mice bearing PC-82 human prostatic tumour xenografts. Eur. J. Nucl. Med., 18, 339-345 (1991).
    • (1991) Eur. J. Nucl. Med. , vol.18 , pp. 339-345
    • Perala-Heape, M.1    Vihko, P.2    Laine, A.3    Heikkila, J.4    Vihko, R.5
  • 9
    • 0024330133 scopus 로고
    • Influence of circulating antigen on the biodistribution and tumour localization of radiolabelled monoclonal antibody in a human tumour: Nude mouse xenograft model
    • Pimm, M. V., Durrant, L. G. and Baldwin, R. W. Influence of circulating antigen on the biodistribution and tumour localization of radiolabelled monoclonal antibody in a human tumour: nude mouse xenograft model. Eur. J. Cancer Clin. Oncol., 25, 1325-1332 (1989).
    • (1989) Eur. J. Cancer Clin. Oncol. , vol.25 , pp. 1325-1332
    • Pimm, M.V.1    Durrant, L.G.2    Baldwin, R.W.3
  • 13
    • 0023004476 scopus 로고
    • Uptake of a monoclonal antibody against CEA (Tumak 431/31) in a human colon tumor (Co-112) xenografted in the nude mouse. Dependence on tumor size and injected dose
    • Duewell, S., Horst, W. and Westera, G. Uptake of a monoclonal antibody against CEA (Tumak 431/31) in a human colon tumor (Co-112) xenografted in the nude mouse. Dependence on tumor size and injected dose. Cancer Immunol Immunother., 23, 101-106 (1986).
    • (1986) Cancer Immunol Immunother. , vol.23 , pp. 101-106
    • Duewell, S.1    Horst, W.2    Westera, G.3
  • 15
    • 0023101534 scopus 로고
    • Quantitative analyses of selective radiolabeled monoclonal antibody localization in metastatic lesions of colorectal cancer patients
    • Colcher, D., Esteban, J. M., Carrasquillo, J. A., Sugarbaker, P., Reynolds, J. C., Bryant, G., Larson, S. M. and Schlom, J. Quantitative analyses of selective radiolabeled monoclonal antibody localization in metastatic lesions of colorectal cancer patients. Cancer Res., 47, 1185-1189 (1987).
    • (1987) Cancer Res. , vol.47 , pp. 1185-1189
    • Colcher, D.1    Esteban, J.M.2    Carrasquillo, J.A.3    Sugarbaker, P.4    Reynolds, J.C.5    Bryant, G.6    Larson, S.M.7    Schlom, J.8
  • 19
    • 0023711704 scopus 로고
    • The malignant B cells from B-chronic lymphocytic leukemia patients release Tac-soluble interleukin-2 receptors
    • Kay, N. E., Burton, J., Wagner, D. and Nelson, D. L. The malignant B cells from B-chronic lymphocytic leukemia patients release Tac-soluble interleukin-2 receptors. Blood, 72, 447-450 (1988).
    • (1988) Blood , vol.72 , pp. 447-450
    • Kay, N.E.1    Burton, J.2    Wagner, D.3    Nelson, D.L.4
  • 20
    • 0025250698 scopus 로고
    • Serum soluble interleukin-2 receptor is associated with clinical and pathologic disease status in hairy cell leukemia
    • Richards, J., Mick, R., Latta, J. M., Daly, K., Ratain, M. J., Vardiman, J. W. and Colomb, H. M. Serum soluble interleukin-2 receptor is associated with clinical and pathologic disease status in hairy cell leukemia. Blood, 76, 1941-1945 (1990).
    • (1990) Blood , vol.76 , pp. 1941-1945
    • Richards, J.1    Mick, R.2    Latta, J.M.3    Daly, K.4    Ratain, M.J.5    Vardiman, J.W.6    Colomb, H.M.7
  • 21
    • 0024364588 scopus 로고
    • Elevated serum-soluble interleukin-2 receptor (Tac antigen) levels in chronic myelogenous leukemia patients with blastic crisis
    • Motoi, T., Uchiyama, T., Hori, T., Itoh, K., Uchino, H. and Ueda, R. Elevated serum-soluble interleukin-2 receptor (Tac antigen) levels in chronic myelogenous leukemia patients with blastic crisis. Blood, 74, 1052-1057 (1989).
    • (1989) Blood , vol.74 , pp. 1052-1057
    • Motoi, T.1    Uchiyama, T.2    Hori, T.3    Itoh, K.4    Uchino, H.5    Ueda, R.6
  • 23
    • 0023916644 scopus 로고
    • Soluble interleukin-2 receptors in systemic lupus erythematosus
    • Wolf, R. E. and Breisford, W. G. Soluble interleukin-2 receptors in systemic lupus erythematosus. Arthritis Rheum., 31, 729-735 (1988).
    • (1988) Arthritis Rheum. , vol.31 , pp. 729-735
    • Wolf, R.E.1    Breisford, W.G.2
  • 24
    • 0025947011 scopus 로고
    • Increased soluble interleukin 2 receptor levels in autoimmune thyroid disease
    • Nakanishi, K., Taniguchi, Y. and Ohta, Y. Increased soluble interleukin 2 receptor levels in autoimmune thyroid disease. Acta Endocrinol. (Copenh.), 125, 253-258 (1991).
    • (1991) Acta Endocrinol. (Copenh.) , vol.125 , pp. 253-258
    • Nakanishi, K.1    Taniguchi, Y.2    Ohta, Y.3
  • 26
    • 0024391130 scopus 로고
    • Multichain interleukin-2 receptor: A target for immunotherapy in lymphoma
    • Waldmann, T. A. Multichain interleukin-2 receptor: a target for immunotherapy in lymphoma. J. Natl. Cancer Inst., 81, 914-923 (1989).
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 914-923
    • Waldmann, T.A.1
  • 27
    • 0019421207 scopus 로고
    • A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells
    • Uchiyama, T., Broder, S. and Waldmann, T. A. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. J. Immunol., 126, 1393-1397 (1981).
    • (1981) J. Immunol. , vol.126 , pp. 1393-1397
    • Uchiyama, T.1    Broder, S.2    Waldmann, T.A.3
  • 28
    • 0021688033 scopus 로고
    • Regulation of interleukin 2 receptor expression: Effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen
    • Depper, J. M., Leonard, W. J., Kronke, M., Noguchi, P. D., Cunningham, R. E., Waldmann, T. A. and Greene, W. C. Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. J. Immnnol., 133, 3054-3061 (1984).
    • (1984) J. Immnnol. , vol.133 , pp. 3054-3061
    • Depper, J.M.1    Leonard, W.J.2    Kronke, M.3    Noguchi, P.D.4    Cunningham, R.E.5    Waldmann, T.A.6    Greene, W.C.7
  • 32
    • 0027092404 scopus 로고
    • Prolongation of graft survival in primate allogratt transplantation by yttrium-90- Labeled anti-Tac in conjunction with granulocyte colonystimulating factor
    • Parenteau, G. L., Dirbas, F. M., Gurmestani, K., Brechbiel, M. W., Bukowski, M. A., Goldman, C. K., Clark, R., Gansow, O. A. and Waldmann, T. A. Prolongation of graft survival in primate allogratt transplantation by yttrium-90-labeled anti-Tac in conjunction with granulocyte colonystimulating factor. Transplantation, 54, 963-968 (1992).
    • (1992) Transplantation , vol.54 , pp. 963-968
    • Parenteau, G.L.1    Dirbas, F.M.2    Gurmestani, K.3    Brechbiel, M.W.4    Bukowski, M.A.5    Goldman, C.K.6    Clark, R.7    Gansow, O.A.8    Waldmann, T.A.9
  • 33
    • 0028951128 scopus 로고
    • Preparation and characterization of a disulfide-stahilized Fv fragment of the anti-Tac antibody: Comparison with its single-chain analog
    • Webber, K. O., Reiter, Y., Brinkmann, U., Kreitman, R. and Pastan, I. Preparation and characterization of a disulfide-stahilized Fv fragment of the anti-Tac antibody: comparison with its single-chain analog. Mol. Immunol., 32, 249-258 (1995).
    • (1995) Mol. Immunol. , vol.32 , pp. 249-258
    • Webber, K.O.1    Reiter, Y.2    Brinkmann, U.3    Kreitman, R.4    Pastan, I.5
  • 38
    • 0027249714 scopus 로고
    • Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms
    • Yokota, T., Milenic, D. E., Whitlow, M., Wood, J. F., Hubert, S. L. and Schlom, J. Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms. Cancer Res., 53, 3776-3783 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 3776-3783
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Wood, J.F.4    Hubert, S.L.5    Schlom, J.6
  • 39
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota, T., Milenic, D. E., Whitlow, M. and Schlom, J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res., 52, 3402-3408 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Schlom, J.4
  • 40
    • 0021866937 scopus 로고
    • A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac
    • Rubin, L. A., Kurman, C. C., Biddison, W. E., Goldman, N. D. and Nelson, D. L. A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac. Hybridoma, 4, 91-102 (1985).
    • (1985) Hybridoma , vol.4 , pp. 91-102
    • Rubin, L.A.1    Kurman, C.C.2    Biddison, W.E.3    Goldman, N.D.4    Nelson, D.L.5
  • 41
    • 0023753413 scopus 로고
    • Structure-function relationships for the interleukin 2 receptor: Location of ligand and antibody binding sites on the Tac receptor chain by mutational analysis
    • Robb, R. J., Rusk, C. M. and Keeper, M. P. Structure-function relationships for the interleukin 2 receptor: location of ligand and antibody binding sites on the Tac receptor chain by mutational analysis. Proc. Natl. Acad. Sci. USA, 85, 5654-5658 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5654-5658
    • Robb, R.J.1    Rusk, C.M.2    Keeper, M.P.3
  • 42
    • 0019445921 scopus 로고
    • A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells, and on one of two types of helper T cells
    • Uchiyama, T., Nelson, D. L., Fleisher, T. A. and Waldmann, T. A. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells, and on one of two types of helper T cells. J. Immnol., 126, 1398-1403 (1981).
    • (1981) J. Immnol. , vol.126 , pp. 1398-1403
    • Uchiyama, T.1    Nelson, D.L.2    Fleisher, T.A.3    Waldmann, T.A.4
  • 44
    • 0017874586 scopus 로고
    • Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril
    • Fraker, P. J. and Speck, J. C., Jr. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril. Biochem. Biophys. Res. Commun., 80, 849-857 (1978).
    • (1978) Biochem. Biophys. Res. Commun. , vol.80 , pp. 849-857
    • Fraker, P.J.1    Speck Jr., J.C.2
  • 45
    • 77956127888 scopus 로고
    • 131I-labelled human growth hormone of high specific radioactivity
    • 131I-labelled human growth hormone of high specific radioactivity. Biochem. J., 89, 114-123 (1963).
    • (1963) Biochem. J. , vol.89 , pp. 114-123
    • Greenwood, F.C.1    Hunter, W.M.2    Glover, J.S.3
  • 46
    • 0021236693 scopus 로고
    • Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess
    • Lindmo, T., Boven, E., Cuttitta, F., Fedorko, J. and Bunn, P. A., Jr. Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess. J. Immunol. Methods. 72, 77-89 (1984).
    • (1984) J. Immunol. Methods , vol.72 , pp. 77-89
    • Lindmo, T.1    Boven, E.2    Cuttitta, F.3    Fedorko, J.4    Bunn Jr., P.A.5
  • 48
    • 0029665818 scopus 로고    scopus 로고
    • Metabolism of Tac (IL2Rα): Physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding
    • Junghans, R. P. and Waldmann, T. A. Metabolism of Tac (IL2Rα): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding. J. Exp. Med., 183, 1587-1602 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1587-1602
    • Junghans, R.P.1    Waldmann, T.A.2
  • 49
    • 0013910824 scopus 로고
    • Insulin in blood and insulin antibodies
    • Berson, S. A. and Yalow, R. S. Insulin in blood and insulin antibodies. Am. J. Med., 40, 676-690 (1966).
    • (1966) Am. J. Med. , vol.40 , pp. 676-690
    • Berson, S.A.1    Yalow, R.S.2
  • 50
    • 0023261755 scopus 로고
    • A soluble interleukin 2 receptor produced by a normal alloreactive human T cell clone binds interleukin 2 with low affinity
    • Jacques, Y., Le Mauff, B., Boeffard, F., Godard, A. and Soulillou, J. P. A soluble interleukin 2 receptor produced by a normal alloreactive human T cell clone binds interleukin 2 with low affinity. J. Immunol., 139, 2308-2316 (1987).
    • (1987) J. Immunol. , vol.139 , pp. 2308-2316
    • Jacques, Y.1    Le Mauff, B.2    Boeffard, F.3    Godard, A.4    Soulillou, J.P.5
  • 51
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman, F. D., Madden, K. B., Morris, S. C., Holmes, J. M., Boiani, N., Katona, I. M. and Maliszewski, C. R. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J. Immunol., 151, 1235-1244 (1993).
    • (1993) J. Immunol. , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.