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Volumn 127, Issue 5 SUPPL., 1997, Pages

Role of Kupffer cells, endotoxin and free radicals in hepatotoxicity due to prolonged alcohol consumption: Studies in female and male rats

Author keywords

alcohol induced liver injury; endotoxin; free radicals; rats; sex differences

Indexed keywords

FREE RADICAL; ICOSANOID; TUMOR NECROSIS FACTOR ALPHA;

EID: 15444358529     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/127.5.903s     Document Type: Conference Paper
Times cited : (39)

References (30)
  • 1
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi, Y., Bradford, B. U., Gao, W., Bojes, H. K. & Thurman, R. G. (1994) Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20: 453-460.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.U.2    Gao, W.3    Bojes, H.K.4    Thurman, R.G.5
  • 2
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi, Y., Moore, L. E., Bradford, B. U., Gao, W. & Thurman, R. G. (1995) Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 108: 218-224.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 4
    • 0029781891 scopus 로고    scopus 로고
    • Acute alcohol produces hypoxia directly in rat liver tissue in vivo: Role of Kupffer cells
    • Arteel, G. E., Raleigh, J. A., Bradford, B. U. & Thurman, R. G. (1996) Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells. Am. J. Physiol. 271: G494-G500.
    • (1996) Am. J. Physiol. , vol.271
    • Arteel, G.E.1    Raleigh, J.A.2    Bradford, B.U.3    Thurman, R.G.4
  • 5
    • 0028785458 scopus 로고
    • Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
    • Arteel, G. E., Thurman, R. G., Yates, J. M. & Raleigh, J. A. (1995) Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br. J. Cancer 72: 889-895.
    • (1995) Br. J. Cancer , vol.72 , pp. 889-895
    • Arteel, G.E.1    Thurman, R.G.2    Yates, J.M.3    Raleigh, J.A.4
  • 7
    • 0008954754 scopus 로고
    • Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell
    • Bernstein, J., Videla, L. & Israel, Y. (1973) Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell. Biochem. J. 134: 515-521.
    • (1973) Biochem. J. , vol.134 , pp. 515-521
    • Bernstein, J.1    Videla, L.2    Israel, Y.3
  • 8
    • 0027156592 scopus 로고
    • Kupffer cells are required for the swift increase in alcohol metabolism
    • Bradford, B. U., Misra, U. K. & Thurman, R. G. (1993) Kupffer cells are required for the swift increase in alcohol metabolism. Res. Commun. Subst. Abuse 14: 1-6.
    • (1993) Res. Commun. Subst. Abuse , vol.14 , pp. 1-6
    • Bradford, B.U.1    Misra, U.K.2    Thurman, R.G.3
  • 9
    • 0024505693 scopus 로고
    • Comparative study of cytotoxicity, tumor necrosis factor, and prostaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells, and murine inflammatory liver macrophages
    • Decker, T., Lohmann-Matthes, M. L., Karck, U., Peters, T. & Decker, K. (1989) Comparative study of cytotoxicity, tumor necrosis factor, and prostaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells, and murine inflammatory liver macrophages. J. Leukocyte Biol. 45: 139-146.
    • (1989) J. Leukocyte Biol. , vol.45 , pp. 139-146
    • Decker, T.1    Lohmann-Matthes, M.L.2    Karck, U.3    Peters, T.4    Decker, K.5
  • 10
    • 0021170722 scopus 로고
    • Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats
    • French, S. W., Benson, N. C. & Sun, P. S. (1984) Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats. Hepatology 4: 912-917.
    • (1984) Hepatology , vol.4 , pp. 912-917
    • French, S.W.1    Benson, N.C.2    Sun, P.S.3
  • 11
    • 0028952855 scopus 로고
    • Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species
    • Gao, W., Connor, H. D., Lemasters, J. J., Mason, R. P. & Thurman, R. G. (1995) Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species. Transplantation 59: 674-679.
    • (1995) Transplantation , vol.59 , pp. 674-679
    • Gao, W.1    Connor, H.D.2    Lemasters, J.J.3    Mason, R.P.4    Thurman, R.G.5
  • 12
    • 0027716912 scopus 로고
    • Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat
    • Goto, M., Lemasters, J. J. & Thurman, R. G. (1994) Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat. J. Pharmacol. Exp. Ther. 267: 1264-1268.
    • (1994) J. Pharmacol. Exp. Ther. , vol.267 , pp. 1264-1268
    • Goto, M.1    Lemasters, J.J.2    Thurman, R.G.3
  • 14
    • 15444361704 scopus 로고    scopus 로고
    • Development of a new model to study increased susceptibility to alcoholic hepatitis in female rats
    • in press
    • Iimuro, Y., Frankenberg, M. V., Bradford, B. U. & Thurman, R. G. (1996) Development of a new model to study increased susceptibility to alcoholic hepatitis in female rats. Am. J. Physiol., 1997. (in press).
    • (1996) Am. J. Physiol.
    • Iimuro, Y.1    Frankenberg, M.V.2    Bradford, B.U.3    Thurman, R.G.4
  • 15
    • 10544240898 scopus 로고
    • Nimodipine, a dihydropyridine-type calcium channel blocker, prevents alcoholic hepatitis due to chronic intragastric ethanol exposure in the rat
    • abs.
    • Iimuro, Y., Ikejima, K., Bradford, B. U. & Thurman, R. G. (1995) Nimodipine, a dihydropyridine-type calcium channel blocker, prevents alcoholic hepatitis due to chronic intragastric ethanol exposure in the rat. Hepatology 22: 548 (abs.).
    • (1995) Hepatology , vol.22 , pp. 548
    • Iimuro, Y.1    Ikejima, K.2    Bradford, B.U.3    Thurman, R.G.4
  • 16
    • 2442712442 scopus 로고
    • Intralobular hepatic pyridine nucleotide fluorescence: Evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia
    • Ji, S., Lemasters, J. J. & Thurman, R. G. (1982) Intralobular hepatic pyridine nucleotide fluorescence: evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia. Proc. Natl. Acad. Sci. U.S.A. 80: 5415-5419.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.80 , pp. 5415-5419
    • Ji, S.1    Lemasters, J.J.2    Thurman, R.G.3
  • 19
    • 85047680729 scopus 로고
    • Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury
    • Lefer, A. M., Weyrich, A. S. & Buerke, M. (1994) Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury. Cardiovasc. Res. 28: 289-294.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 289-294
    • Lefer, A.M.1    Weyrich, A.S.2    Buerke, M.3
  • 20
    • 0026042412 scopus 로고
    • Hepatic, metabolic and toxic effects of ethanol: 1991 up-date
    • Lieber, C. S. (1991) Hepatic, metabolic and toxic effects of ethanol: 1991 up-date. Alcohol. Clin. Exp. Res. 15: 573-592.
    • (1991) Alcohol. Clin. Exp. Res. , vol.15 , pp. 573-592
    • Lieber, C.S.1
  • 22
    • 0020776244 scopus 로고
    • 2 uptake in periportal and pericentral regions of liver lobule: Stop-flow experiments with perfused liver
    • 2 uptake in periportal and pericentral regions of liver lobule: stop-flow experiments with perfused liver. Am. J. Physiol. 244: G656-G659.
    • (1983) Am. J. Physiol. , vol.244
    • Matsumura, T.1    Thurman, R.G.2
  • 23
    • 0345447756 scopus 로고
    • In vivo microscopy of the effects of ethanol on the liver
    • Watson, R. R., ed. Humana Press, Totowa, NJ
    • McCuskey, R. S. (1991) In vivo microscopy of the effects of ethanol on the liver. In: Liver Pathology and Alcohol (Watson, R. R., ed.), pp. 563-570. Humana Press, Totowa, NJ.
    • (1991) Liver Pathology and Alcohol , pp. 563-570
    • McCuskey, R.S.1
  • 25
    • 0027175416 scopus 로고
    • Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver
    • Oshita, M.,Takei, Y., Kawano, S., Iimuro, Y., Kadiiska, M., Qun-hui, X. & Thurman, R. G. (1993) Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver. J. Clin. Invest. 91: 1337-1342.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1337-1342
    • Oshita, M.1    Takei, Y.2    Kawano, S.3    Iimuro, Y.4    Kadiiska, M.5    Qun-hui, X.6    Thurman, R.G.7
  • 26
  • 27
    • 0017571999 scopus 로고
    • Increased hepatic oxygenation following ethanol administration in the baboon
    • Shaw, S., Heller, E. A., Friedman, H. S. & Lieber, C. S. (1977) Increased hepatic oxygenation following ethanol administration in the baboon. Proc. Soc. Exp. Biol. Med. 156: 509-513.
    • (1977) Proc. Soc. Exp. Biol. Med. , vol.156 , pp. 509-513
    • Shaw, S.1    Heller, E.A.2    Friedman, H.S.3    Lieber, C.S.4
  • 28
    • 0000882584 scopus 로고
    • TNFα and IL-6 in alcoholic liver disease
    • Wisse, E., Knook, D. L. & McCuskey, R. S., eds., 3rd ed. Kupffer Cell Foundation, Leiden, The Netherlands
    • Stahnke, L. L., Hill, D. B. & Allen, J. I. (1991) TNFα and IL-6 in alcoholic liver disease. In: Cells of the Hepatic Sinusoid (Wisse, E., Knook, D. L. & McCuskey, R. S., eds.), 3rd ed., pp. 472-475. Kupffer Cell Foundation, Leiden, The Netherlands.
    • (1991) Cells of the Hepatic Sinusoid , pp. 472-475
    • Stahnke, L.L.1    Hill, D.B.2    Allen, J.I.3
  • 29
    • 0021925871 scopus 로고
    • SCOPE: Metabolic fluxes in periportal and pericentral regions of the liver lobule
    • Thurman, R. G. & Kauffman, F. C. (1985) SCOPE: Metabolic fluxes in periportal and pericentral regions of the liver lobule. Hepatology 5: 144-151.
    • (1985) Hepatology , vol.5 , pp. 144-151
    • Thurman, R.G.1    Kauffman, F.C.2
  • 30
    • 0018854977 scopus 로고
    • The swift increase in alcohol metabolism. Time course for the increase in hepatic oxygen uptake and the involvement of glycolysis
    • Yuki, T. & Thurman, R. G. (1980) The swift increase in alcohol metabolism. Time course for the increase in hepatic oxygen uptake and the involvement of glycolysis. Biochem. J. 186: 119-126.
    • (1980) Biochem. J. , vol.186 , pp. 119-126
    • Yuki, T.1    Thurman, R.G.2


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