Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III

Molecular and General Genetics

Volumn 260, Issue 2-3, 1998, Pages 280-288

  Stewart, H I ^a   O'Neil, N J ^a   Janke, D L ^a   Franz, N W ^a   Chamberlin, H M ^a,b   Howell, A M ^a   Gilchrist, E J ^a   Ha, T T ^a   Kuervers, L M ^a   Vatcher, G P ^a   Danielson, J L ^a   Baillie, D L ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Caenorhabditis elegans; Essential genes; Genome organization; sDp3

Indexed keywords

ARTICLE; CAENORHABDITIS ELEGANS; CHROMOSOME 3; CHROMOSOME DAMAGE; CONTROLLED STUDY; GENE CLUSTER; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC COMPLEMENTATION; LETHAL MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STATISTICS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHROMOSOME MAPPING; ETHYL METHANESULFONATE; GAMMA RAYS; GENES, LETHAL; GENETIC COMPLEMENTATION TEST; HELMINTH PROTEINS; MALE; MUTATION; PHENOTYPE; PHYSICAL CHROMOSOME MAPPING; POLYMERASE CHAIN REACTION; ULTRAVIOLET RAYS;

CAENORHABDITIS ELEGANS; INVERTEBRATA; NEMATODA;

EID: 15444356255     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050896     Document Type: Article

References (32)

1. Barnes TM, Kohara Y, Coulson A, Hekimi S (1995) Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. Genetics 141:159-179
2. Barstead RJ, Kleiman L, Waterston RH (1991) Cloning, sequencing, and mapping of an alpha-actinin gene from the nematode Caenorhabditis elegans. Cell Motil Cytoskeleton 20:69-78
3. Brenner S (1974) The genetics of Caenorhahditis elegans. Genetics 77:71-94
4. Clark DV (1990) The unc-22(IV) region of Caenorhabditis elegans: genetic analysis and molecular mapping. PhD Thesis, Simon Fraser University, Burnaby, BC, Canada
5. Clark DV, Baillie DL (1992) Genetic analysis and complementation by germ-line transformation of lethal mutations in the unc-22 IV region of Caenorhabditis elegans. Mol Gen Genet 232:97-105
6. Clark DV, Rogalski TM, Donati LM, Baillie DL (1988) The unc-22(IV) region of Caenorhabditis elegans: genetic analysis of lethal mutations. Genetics 119:345-353
7. Cox GN, Staprans S, Edgar RS (1981) The cuticle of C. elegans. II. Stage-specific changes in ultrastructure and protein composition during postembryonic development. Dev Biol 86:456-470
8. Ellis RE, Jacobson DM, Horvitz HR (1991) Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 129:79-94
9. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-811
10. Gatewood BK, Bucher EA (1997) The mup-4 locus in Caenorhabditis elegans is essential for hypodermal integrity, organismal morphogenesis and embryonic body wall muscle position. Genetics 146:165-183
11. Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG (1996) Life with 6000 genes. Science 274:563-567
12. Hodgkin J, Durbin R, Martinellie S (1997) 1997 genetic map of Caenorhabditis elegans. Caenorhabditis Genetics Center. St. Paul, Minn
13. Horvitz HR, Brenner S, Hodgkin J, Herman RK (1979) A uniform genetic nomenclature for the nematode C. elegans. Mol Gen Genet 175:129-133
14. Howell AM, Rose AM (1990) Essential genes in the hDf6 region of chromosome I in Caenorhabditis elegans. Genetics 126:583-592
15. Janke DL, Schein JE, Ha T, Franz NW, O'Neil NJ, Vatcher GP, Stewart HI, Kuervers LK, Baillie DL, Rose AM (1997) Interpreting a sequenced genome: toward a cosmid transgenic library of Caenorhabditis elegans. Genome Res 7:974-985
16. Jansen G, Hazendonk E, Thijssen KL, Plasterk RHA (1997) Reverse genetics by chemical mutagenesis in Caenorhabditis elegans. Nat Genet 17:119-121
17. Johnsen RC, Baillie DL (1991) Genetic analysis of a major segment [LGV(left)] of the genome of Caenorhabditis elegans. Genetics 129:735-752
18. Johnsen RC, Baillie DL (1997) Mutation. In: Riddle D. Blumenthal T, Meyer B, Priess J (eds) C. elegans II. Cold Spring Harbor Laboratory Press, Cold Spring Harbor New York pp 79-95
19. Kimble J, Hirsh D (1979) The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans. Dev Biol 70:396-417
20. McKim KS, Starr T, Rose AM (1992) Genetic and molecular analysis of the dpy-14 region in Caenorhabditis elegans. Mol Gen Genet 233:241-251
21. Rogalski TM, Baillie DL (1985) Genetic organization of the unc-22 IV gene and the adjacent region in C. elegans. Mol Gen Genet 201:409-414
22. Rogalski TM, Moerman DG, Baillie DL (1982) Essential genes and deficiencies in the unc-22 IV region of C. elegans. Genetics 102:725-736
23. Rosenbluth RE, Cuddeford C, Baillie DL (1985) Mutagenesis in Caenorhabditis elegans. II. A spectrum of mutational events induced with 1500 R of γ-radiation. Genetics 109:493-511
24. Rosenbluth RE, Rogalski TM, Johnsen RC, Addison EM, Baillie DE (1988) Genomic organization in Caenorhabditis elegans: deficiency mapping on linkage group V(left). Genet Res 52:105-118
25. Sigurdson DC, Spanier GJ, Herman RK (1984) Caenorhabditis elegans deficiency mapping. Genetics 108:331-345
26. Stewart HI, Rosenbluth RE, Baillie DE (1991) Most ultraviolet irradiation induced mutations in the nematode Caenorhabditis elegans are chromosomal rearrangements. Mutat Res 249:37-54
27. Sulston J, Horvitz HR (1977) Postembryonic lineages of the nematode Caenorhabditis elegans. Dev Biol 56:110-156
28. Vatcher GP, Thacker CM, Kaletta T, Schnabel H, Schnabel R, Baillie DL (1998) Serine hydroxymethyltransferase is maternally essential in Caenorhabditis elegans. J Biol Chem 273:6066-6073
29. Waterston RH, Sulston JE (1995) The genome of Caenorhabditis clegans. Proc Natl Acad Sci USA 92:10836-10840
30. Waterston RH, Sulston JE, Coulson AR (1997) The genome. In: Riddle D, Blumenthal T, Meyer B, Priess J (eds) C. elegans II. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp 23-47
31. Williams BD, Schrank B, Huynh C, Shownkeen R, Waterston RH (1992) A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics 131:609-624
32. Wilson R, Ainscough R, Anderson K, Baynes C, Berks M, Burton J, Connell M, Bonfield J, Copsey T, Cooper J (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368:32-38