Quercetin prevents UV-induced local immunosuppression, but does not affect UV-induced tumor growth in SKH-1 hairless mice

Photochemistry and Photobiology

Volumn 65, Issue 4, 1997, Pages 736-744

  Steerenberg, P A ^a   Garssen, J ^a   Dortant, P ^a   Van De Vliet, H ^a   Geerse, L ^a   Verlaan, A P J ^a   Goettsch, W ^a   Sontag, Y ^b   Norval, M ^c   Gibbs, N K ^d   Bueno de Mesquita, H B ^a   Van Loveren, H ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 15444345049     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1997.tb01918.x     Document Type: Article

References (58)

1. Block, G., B. Patterson and A. Subar (1992) Fruit, vegetables, and cancer prevention. A review of the epidemiological evidence. Nutr. Cancer 18, 1-29.
2. Willett, W. C. (1994) Micronutrients and cancer risk. Am. J. Clin. Nutr. 59(Suppl), 1162S-1165S.
3. Block, G. (1993) Micronutrients and cancer: time for action. J. Natl. Cancer Inst. 8511, 846-847.
4. Steinmetz, K. A. and J. D. Potter (1991) Vegetables, fruits and cancer. II. Mechanisms. Cancer Causes Control 2, 427-442.
5. Verma, A. K., J. A. Johnson, M. N. Gould and M. A. Tanner (1988) Inhibition of 7,12-dimethylbenz(a)anthracene-and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin. Cancer Res. 48, 5754-5758.
6. Chang, R. L., M. T. Huang, A. W. Wood, C. Q. Wong, H. L. Newmark, H. Yagi, J. M. Sayer, D. M. Jerina and A. H. Conney (1985) Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo(a)pyrene and (±)-7β,8α-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene on mouse skin and in the newborn mouse. Carcinogenesis 8, 1127-1133.
7. Yasukawa, K., M. Takido, M. Takeuchi, Y. Sato, K. Nitta and S. Nakagawa (1990) Inhibitory effects of flavonol glycosides on 12-0-tetradecanoylphorbol-13-acetate-induced tumor promotion. Chem. Pharm. Bull. 38, 774-776.
8. Wang, Z. Y., M. T. Huang, T. Ferraro, C. Q. Wong, H. Newmark, C. S. Yang and A. H. Conney (1991) Inhibitory effect of orally administered green tea on ultraviolet B light (UVB)-induced carcinogenesis in the skin of SKH-1 mice. Proc. Am. Assoc. Cancer Res. 32, 129.
9. Wang, Z. Y., M. T. Huang, T. Ferraro, C. Q. Wong, Y. R. Lou, K. Reuhl, M. Itraopoulos, C. S. Yang and A. H. Conney (1992) Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-O tetradecanoylphorbol-13-acetate in the skin of SKH-1 mice. Cancer Res. 52, 1162-1170.
10. Yoshizawa, S., T. Horiuchi, H. Fujiki, T. Yoshida, T. Okuda and T. Sugimura (1987) Antitumor promoting activity of (-) epigallocatechin gallate the main constituent of "tannin" in green tea. Phytother. Res. 1, 44-47.
11. Fujita, Y., T. Yamane, M. Tanaka, K. Kuwata, J. Okuzumi, T. Takahashi, H. Fujiki and T. Okuda (1989) Inhibitory effect of (-)epigallocatechin gallate on carcinogenesis with N-ethyl-N-nitro-N-nitrosoguanidine in mouse duodenum. Jpn. J. Cancer Res. 80, 503-505.
12. Wang, Z. Y., W. A. Khan, D. A. Bickers and H. Mukhtar (1989) Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols. Carcinogenesis 10, 411-415.
13. Wang, Z. Y., M. T. Huang, J. Y. Hong, A. H. Conney and C. S. Yang (1991) Inhibition of N-nitrosodiehylamine (NDEA)-induced lung and forestomach tumorigenesis in A/J mice by green tea. Proc. Am. Assoc. Cancer Res. 32, 125.
14. Huang, M. T., Z. Y. Wang, C. T. Ho, T. Ferraro, H. Newmark, J. M. Mitchell, J. D. Laskin and A. H. Conney (1991) Inhibitory effect of topical application of a green tea polyphenol fraction on 12-O-tetradecanoylphorbol-13 acetate (TPA)-induced ornithine decarboxylase activity, inflammation and tumor promotion in the skin of CD-1 mice. Proc. Am. Assoc. Cancer Res. 32, 129.
15. Chung, F. L., M. A. Morse and Y. Xu (1993) Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea. Ann. N.Y. Acad. Sci. 686, 186-201.
16. Han, C. and Y. Xu (1990) The effect of chinese tea on occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine in rats. Biomed. Environ. Sci. 3, 35-42
17. Alink, G. M., H. A. Kuiper, V. M. H. Hollanders and J. H. Koeman (1993) Effect of heat processing and of vegetables and fruit in human diets on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. Carcinogenesis 14, 519-524.
18. Steinmetz, K. A. and J. D. Potter (1991) Vegetables, fruits, and cancer. I. Epidemiology. Cancer Causes Control 2, 325-357.
19. Sinha, S. and S. Jain (1994) Natural products as anticancer agents. In Progress in Drug Research (Edited by E. Jucker), pp. 53-132. Birkhäuser Verlag Basel, Switzerland.
20. Middleton, E., Jr. and C. Kandaswami (1992) Effects of flavonoids on immune and inflammatory cell functions. Biochem. Pharm. 43, 1167-1179.
21. Hartog, M. G., D. Kromhout, C. Aravanis, H. Blackburn, R. Buzina, F. Fidanza, S. Giampaoli, A. Jansen, A. Menotti, S. Nedeljkovic, M. Pekkarinen, B. S. Simic, H. Toshima, E. J. M. Feskens, P. C. H. Hollman and M. B. Katan (1995) Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Arch. Intern. Med. 155, 381-386.
22. Hertog, M. G., P. C. H. Hollman, M. B. Katan and D. Kromhout (1993) Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr. Cancer 20, 21-29.
23. Hosokawa, N., Y. Hosokawa, T. Sakai, M. Yoshida, N. Marvi et al. (1987) Inhibitory effect of quercetin on the synthesis of a possibly cell-cycle-related 17-kDa protein in human colon cancer cells. Int. J. Cancer 45, 1119-1124.
24. Ranelletti, F. O., R. Ricci, L. M. Larocca, N. Maggiano, A. Capelli et al. (1992) Growth-inhibitory effect of quercetin and presence of type-II estrogen binding sites in human colon cancer cell lines and primary colorectal tumors. Int. J. Cancer 50, 486-492.
25. Zhu, B. T. and J. G. Liehr (1994) Quercetin increases the severity of estradiol-induced tumorigenesis in hamster kidney. Toxicol. Appl. Pharmacol. 125, 149-158.
26. Dunnick, J. K. and J. R. Hailey (1992) Toxicity and carcinogenicity studies of quercetin, a natural component of foods. Fund. Appl. Toxicol. 19, 423-431.
27. Ward, E. C., M. J. Murray, L. D. Lauer, R. V. Houst and J. H. Dean (1986) Persistent suppression of humoral and cell-mediated immunity in mice following exposure to the polycyclic aromatic hydrocarcon 7,12 dimethylbenz(a)anthracene. Int. J. Immunopharmacol. 8, 13-22.
28. Blanton, R. H., M. Lyte, M. J. Meyers and P. H. Bick (1986) Immunomodulation by polyaromatic hydrocarbons. Cancer Res. 46, 2735-2739.
29. Kripke, M. and W. Morison (1985) Modulation of immune function by UV radiation. J. Invest. Dermatol. 85, 62s-66s.
30. Noonan, F. P., E. C. DeFabo and M. L. Kripke (1981) Suppression of contact hypersensitivity by UV radiation and its relationship to UV-induced suppression of tumor immunity. Photochem. Photobiol. 43, 683-689.
31. Yee, G. K., S. E. Ullrich and M. L. Kripke (1989) The role of suppressor factors in the regulation of immune responses by ultraviolet radiation-induced suppressor T lymphocytes. I. Activity of suppressor cell culture supernatants. Cell. Immunol. 121, 74-87.
32. Mukhtar, H., S. K. Katiyar and R. Agarwal (1994) Green tea and skin - anticarcinogenic effects. J. Invest. Dermatol. 102, 1.
33. Black, H. S., J. I. Thornby, J. Gerguis and W. Lenger (1992) Influence of dietary omega-6, -3 fatty acid sources on the initiation and promotion stages of photocarcinogenesis. Photochem. Photobiol. 56, 195-199.
34. Fischer, M. A. and H. S. Black (1991) Modification of membrane composition, eicosanoid metabolism, and immunores ponsiveness by dietary omega-3 and omega-6 fatty acid sources, modulators of ultraviolet-carcinogenesis. Photochem. Photobiol. 54, 381-387.
35. Robinson, A. B., A. Hunsberger and F. C. Westall (1994) Suppression of squamous cell carcinoma in hairless mice by dietary nutrient variation. Mechanisms Ageing Dev. 76, 201-241.
36. Reeve, V. E., M. Bosnic, E. Rozinova and C. Boehm-Wilcox (1993) A garlic extract protects from ultraviolet B (280-320 nm) radiation-induced suppression of contact hypersensitivity. Photochem. Photobiol. 58, 813-817.
37. Katiyar, S. K., C. A. Elmets, R. Agarwal and H. Mukhtar (1995) Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. Photochem. Photobiol. 62, 855-861.
38. Moolenbeek, C. and E. J. Ruitenberg (1981) The swiss roll: a simple technique for histological studies of rodent intestine. Lab. Animals 15, 57-59.
39. Lever, W. F. (1990) Histopathology of the Skin, 7th ed. J. B. Lippincott Company, Philadelphia, PA.
40. Kraal, G., M. Breel, M Janse and G Bruin (1986) Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. J. Exp. Med. 163, 981-997.
41. van Loveren, H., N. Gianotten, C. F. M. Hendriksen, H. J. Schuurman and J. W. van der Laan (1994) Assessment of immunotoxicity of buprenorphine. Lab. Animals 28, 355-363.
42. Goettsch, W., Y. Hatori and R. P. Sharma (1992) Adjuvant activity of all-trans-retinoic acid in C57B1/6 mice. Int. J. Immunopharmacol. 14, 143-150.
43. Norval, M., C. R. McIntyre, T. J. Simpson, S. E. M. Howie and E. Bardshiri (1988) Quantification of urocanic acid isomers in murine skin during development and after irradiation with ultraviolet B light. Photodermatology 5, 179-186.
44. Gibbs, N. K., M. Norval, N. J. Traynor, M. Wolf, B. E. Johnson and J. Crosby (1993) Action spectra for the trans to cis photoisomerization of urocanic acid in vitro and in mouse skin. Photochem. Photobiol. 57, 584-590.
45. De Gruijl, F. R., J. B. van der Meer and J. C. van der Leun (1983) Dose-time dependency of tumor formation by chronic UV-exposure. Photochem. Photobiol. 37, 53-62.
46. Brenner, M. B., J. McLean, H. Scheft, J. Riberdy, S.-L. Ang, S. G. Seidman, P. Devlin and M. S. Krangel (1987) Two forms of the T cell γ protein found on peripheral blood cytotoxic lymphocytes. Nature 325, 689.
47. Bluestone, J. A., R. Q. Cron, T. A. Barret, B. Houlden, A. I. Sperling. A. Dent, S. Hedrick, B. Rellahan and L. A. Matis (1991) Repertoire development and ligand specifity of murine TCRγδ cells. Immunol Rev. 120, 5.
48. + CTL clones is affected by mutations at position 152 and 156. J. Immunol. 144, 4156-4162.
49. Alcalay, J. and M. Kripke (1991) Antigen-presenting activity of draining lymph node cells from mice painted with a contact allergen during ultraviolet carcinogenesis. J. Immunol. 146, 1717-1721.
50. Sontag, Y., J. Garssen, F. R. de Gruijl, J. C. van der Leun, W. A. van Vloten and H. van Loveren (1994) Ultraviolet radiation-induced impairment of the early initiating and the late effector phases of contact hypersensitivity to picryl chloride: regulation by different mechanisms. J. Invest. Dermatol. 102, 923-927.
51. El-Ghorr, A. A., M. Norval, M. B. Lappin and J. C. Crosby (1995) The effect of chronic low-dose UVB radiation on Langerhans cells, sunburn cells, urocanic acid isomers, contact sensitivity and serum immunoglobulins in mice. Photochem. Photobiol. 62, 326-332.
52. Richters, C. D., E. A. Reits, A. M. van Pelt, M. J. Hoekstra and J. van Baare (1996) Effect of low dose UVB irradiation on migratory properties and functional capacities of human skin dendritic cells. Clin. Exp. Immunol. 104, 191-197.
53. Grabbe, S. and R. D. Granstein (1994) Mechanisms of ultraviolet radiation carcinogenesis. Chem. Immunol. 58, 291-313.
54. Perez, M. I. and R. L. Edelson (1994) Regulation of immunity by ultraviolet radiation and photosensitized reactions. Chem. Immunol. 58, 314-330.
55. Ross, J. A., S. E. M. Howie, M. Norval, J. Maingay and T. J. Simpson (1986) Ultraviolet-induced urocanic acid suppresses delayed-type hypersensitivity to herpes simplex virus in mice. J. Invest. Dermatol. 87, 630-633.
56. Noonan, F. A., E. DeFabo and H. Morrison (1988) Cis-urocanic acid, a product formed by ultraviolet B irradiation of the skin, initiates an antigen presentation defect in splenic dendritic cells in vivo. J. Invest. Dermatol. 90, 92-99.
57. Kimber, I., M. R. Holliday and R. J. Dearman (1995) Cytokine regulation of chemical sensitization. Toxicol. Lett. 82-83, 491-496.
58. Wang, B., S. Kondo, G. M. Shivji, H. Fujisawa, T. W. Mak and D. N. Sauder (1996) Tumour necrosis factor receptor II (p75) signalling is required for the migration of Langerhans' cells. Immunology 88, 284-288.