A Novel BRCA2-Binding Protein and Breast and Ovarian Tumorigenesis

New England Journal of Medicine

Volumn 350, Issue 12, 2004, Pages 1252-1253

  King, Mary Claire ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BRCA2 BINDING PROTEIN; BRCA2 PROTEIN; CYCLIN D1; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOGENESIS; CANCER GENETICS; GENE AMPLIFICATION; GENE MUTATION; GENE OVEREXPRESSION; ONCOGENE; ONCOGENE EMSY; ONCOGENE MYC; ONCOGENE NEU; OVARY CANCER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

BRCA2 PROTEIN; BREAST NEOPLASMS; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA2; HUMANS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; PROGNOSIS; REPRESSOR PROTEINS; UP-REGULATION;

EID: 1542720457     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcibr033528     Document Type: Article

References (4)

1. Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000;14: 927-39.
2. Dong Y, Hakimi MA, Chen X, et al. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Mol Cell 2003;12: 1087-99.
3. Hughes-Davies L, Huntsman D, Ruas M, et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115:523-35.
4. Milner J, Ponder B, Hughes-Davies L, Seltmann M, Kouzarides T. Transcriptional activation functions in BRCA2. Nature 1997;386: 772-3.