Industry testing of toxic pesticides on human subjects concluded "No effect" despite the evidence [1]

Environmental Health Perspectives

Volumn 112, Issue 3, 2004, Pages

  Sass, Jennifer B ^a   Needleman, Herbert L ^b  

^a NATURAL RESOURCES DEFENSE COUNCIL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ALDICARB; ATROPINE; CARBAMATE PESTICIDE; DICHLORVOS; INDUSTRIAL CHEMICAL; PESTICIDE;

CLINICAL FEATURE; ECOTOXICITY; ENVIRONMENTAL MANAGEMENT; ENVIRONMENTAL MONITORING; ENVIRONMENTAL PROTECTION; ENZYME ACTIVITY; ENZYME INHIBITION; FOOD CONTAMINATION; FOOD POISONING; HUMAN; LETTER; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TOXICITY TESTING;

AGE FACTORS; CHEMICAL INDUSTRY; CONFLICT OF INTEREST; HUMANS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PESTICIDES; REPRODUCIBILITY OF RESULTS; SAMPLE SIZE; TOXICITY TESTS; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

EID: 1542708084     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (10)

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2. Bekelman JE, Li Y, Gross CP. 2003. Scope and impact of financial conflicts of interest in biomedical research: A systematic review. JAMA 289:454-45.
3. Goldman LR, Beller M, Jackson RJ. 1990. Aldicarb food poisonings in California, 1985-1988: Toxicity estimates for humans. Arch Environ Health 45: 141-147.
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5. IARC. 1991. Dichlorvos. IARC Monogr Eval Carcinog Risks Hum 53: 267-307
6. Mitka M. 2003. EPA ponders pesticide toxicity testing: considers ending moratorium on human data. JAMA 289(5):535-536.
7. NAS. 2003. Use of Third Party Toxicity Research with Human Research Participants. Project No. STLP-Q-02-02-A. Washington, DC:NAtional Academy of Sciences. Available: http://www4.nas.edu/webcr.nsf/Meeting Display4/STLP-Q-02-02-A?OpenDocument [accessed 11 February 2004].
8. National Research Council. 1977. Drinking Water and Health. Washington, DC:NAtional Academy of Sciences. Available: http://www.nap.edu/books/0309026199/html/index.html [accessed 11 February 2004].
9. U.S. EPA. 1994. Integrated Risk Information System: Dichlorvos (CASRN 62-73-7). Washington, DC:U.S. Environmental Protection Agency. Available: Http://www.epa.gov/iris/ subst/0151.htm [accessed 9 February 2004].
10. Wyld PJ, Watson CE, Nimmo WS, Watson N. 1992. A Safety and Tolerability Study of Aldicarb at Various Dose Levels in Healthy Male and Female Volunteers. Rhone-Poulenc, Lyon, France. Inveresk Clinical Research Report No. 7786. MRID No. 42373-01. HED Doc No 010459. Washington, DC:U.S. Environmental Protection Agency.