Carbonic anhydrase inhibitors. Part 25: Thienothiopyran sulfonamides - A novel class of complexing agents for the preparation of dual enzyme inhibitors

Revue Roumaine de Chimie

Volumn 41, Issue 5-6, 1996, Pages 495-499

  Supuran, Claudiu T ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 1542684244     PISSN: 00353930     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Preceding part: C. T. Supuran and B. W. Clare, J. Med. Chem., submitted
2. For a review see: G. Alzuet, S. Ferrer, J. Borras and C. T. Supuran, Roum. Chem. Quart. Rev., 1994, 2, 000-000.
3. a) T. H. Maren, Physiol Rev., 1967, 47, 595-781;
4. b) T. H. Maren, Drug Dev. Res., 1987, 10, 255-276;
5. c) W. F. Brechue and T. H. Maren, Exp. Eye Res., 1993, 57, 67-78;
6. d) T. H. Maren and C. W. Conroy, J. Biol. Chem., 1993, 268, 26233-26239.
7. a) C. T. Supuran, M. Andruh and I. Puscas., Rev. Roum. Chim., 1990, 35, 393-398;
8. b) C. T. Supuran, G. Manole and M. Andruh, J. Inorg. Biochem., 1993, 49, 97-104;
9. c) C. T. Supuran, Rev. Roum. Chim., 1992, 37, 849-855.
10. C. Luca, M. Bǎrboiu and C. T. Supuran, Rev. Roum. Chim., 1991, 36, 1169-1173.
11. D. N. Silverman and S. Lindskog, Acc. Chem. Res., 1988, 21, 30-36.
12. a) G. S. Ponticello, M. B. Freedman, C. N. Habecker, P. A.Lyle, H. Schwam, S. L. Varga, M. E. Christy, W. C. Randall and J. J. Baldwin, J. Med. Chem., 1987, 30, 591-597;
13. b) J. J. Baldwin, G. S. Ponticello, P. S. Andersen, M. E. Christy, M. A. Murcko, W. C. Randall, H.Schwam, M. F. Sugrue, J. P. Springer, P. Gautheron, J. Grove, P. Mallorga, M. P. Viader. B. M. McKeever and N. A. Navia, J. Med. Chem., 1989, 32, 2510-2513;
14. c) T. J. Blacklock. P. Sohar, J. W. Butcher and E. J. J. Grabowski, J. Org. Chem., 1993, 58, 1672-1679.
15. a) M. F. Sugrue, P. Gautheron, J. Grove, P. Mallorga, M. P. Viader, H. Schwam, J. J. Baldwin, M. E. Christy and G. S. Ponticello, J. Ocul. Pharmacol, 1990, 6, 9-22;
16. b) J. H. Lin, E. H. Ulm and L. E. Los, Drug Metab. Dispos., 1991, 19, 233-238;
17. c) E. A. Lippa et al. (15 authors) Arch. Ophthalmol., 1992, 110; 495-499.
18. W. F. Brechue and T. H. Maren, Invest Ophthalmol. Sci., 1993, 34, 2581-2587.
19. The sulfonamides 4a, b were prepared as described in ref. 7. Metal salts and other reagents were from Aldrich. Bovine CA II was from Sigma Chemical Co.
20. G. Alzuet, J. Casanova, J. A. Ramirez and J. Borras, J. Inorg. Biochem., in press.
21. a) C. T. Supuran, Rev. Roum. Chim., 1993, 35, 229-236;
22. b) G. Manole, O. Maior and C. T. Supuran, Rev. Roum. Chim., 1993, 38, 475-479;
23. c) C. T. Supuran, R. Olar, D. Marinescu and M. Brezeanu, Roum. Chem. Quart. Rev., 1993, 1, 193-204.
24. a) I. Bertini, G. Canti, C. Luchinat and A. Scozzafava, J. Am. Chem. Soc., 1978, 100, 4873-4877;
25. b) X. Ren, A. Sandstrom and S. Lindskog, Eur. J. Biochem., 1988, 173, 73-78.
26. R. Han, A. Looney, K. McNeil, G. Parkin, A.L.Rheingold and B. S. Haggerty, J. Inorg. Biochem., 1993, 49, 105-121.
27. M. Andruh, E. Cristurean, R. Ştefan and C. T. Supuran, Rev. Roum. Chim., 1991, 36, 727-732.
28. T. H. Maren, J. Pharmacol. Ex. Ther., 1960, 130, 26-29.