Arousal responses to somatosensory and mild hypoxic stimuli are depressed during quiet sleep in healthy term infants

Sleep

Volumn 26, Issue 6, 2003, Pages 739-744

  Parslow, Peter M ^a   Harding, Richard ^a   Cranage, Susan M ^a   Adamson, T Michael ^a   Horne, Rosemary S C ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

Author keywords

Arousability; Hypoxia; Sleep; Sudden infant death syndrome

Indexed keywords

OXYGEN;

AROUSAL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPOXIA; INFANCY; INFANT; MALE; NEWBORN; NORMAL HUMAN; OXYGEN SATURATION; PERINATAL PERIOD; PRIORITY JOURNAL; SLEEP; SOMATOSENSORY STIMULATION; ANOXIA; BREATHING; EVOKED SOMATOSENSORY RESPONSE; METABOLISM; PHYSIOLOGY; POLYSOMNOGRAPHY; PROBABILITY;

ANOXIA; AROUSAL; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; HUMANS; INFANT, NEWBORN; MALE; OXYGEN; POLYSOMNOGRAPHY; PROBABILITY; RESPIRATION; SLEEP;

EID: 1542645203     PISSN: 01618105     EISSN: None     Source Type: Journal    
DOI: 10.1093/sleep/26.6.739     Document Type: Article

References (52)

1. Phillipson EA, Sullivan CE. Arousal: The forgotten response to respiratory stimuli. Am Rev Respir Dis 1978;118:807-9.
2. Bowes G. Arousal responses to chemical stimuli during sleep J Dev Physiol 1984,6:207-13
3. Hunt CE The cardiorespiratory hypothesis for sudden infant death syndrome Clin Perinatal 1992;19:757-71.
4. Ariagno R, Nagel L, Guilleminault C. Waking and ventilatory responses during sleep in infants near-miss for Sudden Infant Death Syndrome Sleep 1980;3:351-9
5. Hunt CE Abnormal hypercarbic and hypoxic sleep arousal responses in near-miss SIDS infants. Pediatr Res 1981;15 1462-4.
6. McCulloch K, Brouillette RT, Guzzetta AJ, Hunt CE. Arousal responses in near-miss sudden infant death syndrome and in normal infants. J Pediatr 1982;101:911-7
7. van der Hal AL, Rodriguez AM, Sargent CW, Platzker ACG, Keens TG. Hypoxic and hypercapneic arousal responses and prediction of subsequent apnea in apnea of infancy Pediatrics 1985;75:848-54.
8. Brady JP, McCann EM. Control of ventilation in subsequent siblings of victims of sudden infant death syndrome. J Pediatr 1985,106:212-7.
9. Newman NM, Frost JK, Bury L, Jordan K, Phillips K. Responses to partial nasal obstruction in sleeping infants. Aust Paediatr J 1986,22:111-6.
10. Newman NM, Trinder JA, Phillips KA, Jordan K, Cruiekshank J Arousal deficit, mechanism of the sudden infant death syndrome? Aust Paediatr J 1989:25:196-201
11. Milerad J, Hertzberg T, Wennergren G, Lagercrantz H. Respiratory and arousal responses to hypoxia in apneic infants reinvestigated. Eur J Pediatr 1989,148:565-70.
12. Davidson Ward SL, Bautista DB, Sargent CW, Keens TG. Arousal responses to sensory stimuli in infants at increased risk for sudden infant death syndrome. Am Rev Respir Dis 1990,141 A809.
13. Trinder J, Newman NM, Le Grande M, et al Behavioural and EEG responses to auditory stimuli during sleep in newborn infants and in infants aged 3 months Biol Psychol 1990;31:213-27.
14. Davidson Ward SL, Bautista DB, Keens TG Hypoxic arousal responses in normal infants Pediatrics 1992;89:860-4
15. Dunne KP, Fox GPP, O'Regan M, Matthews TG. Arousal responses in babies at risk of sudden infant death syndrome at different postnatal ages. Ir Med J 1992, 85 19-22.
16. Lewis KW, Bosque EM. Deficient hypoxia awakening response in infants of smoking mothers: possible relationship to sudden infant death syndrome J Pediatr 1995;127 691-9
17. Read PA, Horne RSC, Cranage SM, et al. Dynamic changes in arousal threshold during sleep in the human infant Pediatr Res 1998;43:697-703
18. Campbell AJ, Bolton DPG, Taylor BJ, Sayers RM Responses to an increasing asphyxia in infants: effects of age and sleep state Respir Physiol 1998;112:51-8.
19. McNamara F, Wulbrand H, Thach BT. Characteristics of the infant arousal response. J Appl Physiol 1998,85 2314-21
20. Franco P, Pardou A, Hassid S, et al Auditors arousal thresholds are higher when infants sleep in the prone position J Pediatr 1998,132:240-3.
21. Galland BC, Reeves G, Taylor BJ, Bolton DPG. Sleep position, autonomic function, and arousal. Arch Dis Child Fetal Neonatal Ed 1998;78:F189-94.
22. Franco P, Groswasser J, Hassid S, et al. Prenatal exposure to cigarette smoking is associated with a decrease in arousal in infants. J Pediatr 1999;135 34-8
23. Jeffery H, Megevand A, Page M Why the prone position is a risk factor for sudden infant death syndrome. Pediatrics 1999, 104 263-9
24. Galland BC, Bolton DPG, Taylor BJ, Sayers RM, Williams SM. Ventilatory sensitivity to mild asphyxia: prone versus supine position Arch Dis Child 2000;83:423-8
25. Horne RSC, Sly DJ, Cranage SM, Chau B, Adamson TM. Effects of prematurity on arousal from sleep in the newborn infant. Pediatr Res 2000,47 468-74
26. Horne RSC, Ferens D, Watts A, et al The prone sleeping position impairs arousability in term infants J Pediatr 2001,138.811-6.
27. Horne RSC, Osborne A, Vitkovic J, et al Arousal from sleep in infants is impaired following an infection Earh Hum Develop 2002;66 89-100
28. Fewell JE, Baker SB Arousal from sleep during rapidly developing hypoxemia in lambs. Pediatr Res 1987;22:471-7.
29. Baker SB, Fewell JE. Effects of hyperoxia on the arousal response to upper airway obstruction in lambs. Pediatr Res 1987;21:116-20.
30. Fewell JE, Konduri GG. Influence of repeated exposure to rapidly developing hypoxaemia on the arousal and cardiopulmonary response to rapidly developing hypoxaemia in lambs. J Dev Physiol 1989,11:77-82.
31. Horne RSC, Berger PJ, Bowes G, Walker AM. Effect of sinoaortic denervation on arousal responses to hypotension in newborn lambs. Am J Physiol 1989;256:H434-40
32. Horne RSC, De Preu ND, Berger PJ, Walker AM. Arousal responses to hypertension in lambs effect of sinoaortic denervation. Am J Physiol 1991;260:H1283-9.
33. Walker AM, Carroll J, De Preu ND, Home RSC Modification of arousal responses following hypoxia in newborn lambs Second SIDS International Conference. Sydney, Australia; 1992.
34. Walker AM, Johnston RV, Grant DA, Wilkinson MH. Repetitive hypoxia abolishes arousal from sleep in newborn lambs. In: Rognum TO, ed. Sudden infant death syndrome New trends in the nineties Oslo: Scandinavian University Press; 1995:238-241.
35. Johnston RV, Grant DA, Wilkinson MH, Walker AM. Repetitive hypoxia rapidly depresses arousal from active sleep in newborn lambs. J Physiol 1998;510:651-9.
36. Johnston RV, Grant DA, Wilkinson MH, Walker AM. Repetitive hypoxia rapidly depresses cardio-respiratory responses during active sleep but not quiet sleep in the newborn lamb. J Physiol 1999;519:571-9.
37. Moss TJ, Harding R. Ventilatory and arousal responses of sleeping lambs to respiratory challenges: effect of prenatal maternal anemia. J Appl Physiol 2000;88:641-8.
38. Moss TJ, Harding R Ventilatory and arousal responses to respiratory stimuli of full term, intrauterine growth restricted lambs. Respir Physiol 2001;124:195-204.
39. Phillipson EA, Bowes G, Sullivan CE, Woolf GM. The influence of sleep fragmentation on arousal and ventilatory responses to respiratory stimuli. Sleep 1980;3:281-8.
40. Bowes G Woolf GM, Sullivan CF, Phillipson FA. Effect of sleep fragmentation on ventilatory and arousal responses of sleeping dogs to respiratory stimuli. Am Rev Respir Dis 1980;122:899-908.
41. Issa FQ, McNamara SG, Sullivan CE. Arousal responses to airway occlusion in sleeping dogs: comparison of nasal and tracheal occlusions. J Appl Physiol 1987;62:1832-6.
42. Yasuma F, Kozar LF, Kimoff RJ, Bradley TD, Phillipson EA. Interaction of chemical and mechanical respiratory stimuli in the arousal response to hypoxia in sleeping dogs. Am Rev Respir Dis 1991;143:1274-7.
43. Kim WS, Champagne VL, Gottfried SB, Kimoff RJ Effect of inspiratory pressure support on the arousal response to CO2 in sleeping dogs. J Appl Physiol 1995, 79:1419-25
44. Jeffery HE, Page M, Post EJ, Wood AKW Physiological studies of gastro-esophageal reflux and airway protective responses in the young animal and human infant. Clin Exp Pharmacol Physiol 1995;22:544-9.
45. Galland BC, Wehner NS, Bolton DPG, Taylor BJ. Arousal responses of the newborn piglet to airways obstruction and rebreathing during normothermia and hyperthermia. Reprod Fertil Dev 1996;8 365-71.
46. Cohen G, Henderson-Smart DJ A modified rebreathing method to study the ventilatory response of the newborn to carbon dioxide. J Dev Physiol 1990,14:295-301
47. Cohen G, Malcolm G, Henderson-Smart D Ventilatory response of the newborn infant to mild hypoxia. Pediatr Pulmonol 1997;24:163-72
48. Anders T, Emde R, Parmelee A. A manual of standardized terminology, techniques and criteria for scoring of states of sleep and wakefulness in newborn infants. Los Angeles, Brain Information Service/Brain Research Institute; 1971.
49. Armitage P, Berry G. Statistical methods in medical research. 3rd ed. London: Blackwell Scientific Publications; 1994
50. Parslow PM, Harding R, Cranage SM, Adamson TM, Home RSC. Ventilatory responses preceding hypoxia induced arousal in infants effects of sleep-state. Respir Physiol Neurobiol 2003;136:235-47
51. Katz-Salamon M, Hertzberg T, Lagercrantz H. CO2-sensitivity in newborn and young infants tested by the rebreathing method. Biol Neonate 1991,59:126-32.
52. Parslow P, Horne RSC, Cranage SM, Harding R, Adamson TM. Mild hypoxia increases arousability in sleeping infants up to 6 months of age post-term. Proceedings of the 7th SIDS International Conference, Florence, Italy. August 31-September 4, 2002