Toxicological and metabolic investigations of the safety of N-α-Lauroyl-L-arginine ethyl ester monohydrochloride (LAE)

Food and Chemical Toxicology

Volumn 42, Issue 2, 2004, Pages 245-259

  Ruckman, Stephen A ^a   Rocabayera, Xavier ^b   Borzelleca, Joseph F ^c   Sandusky, Chad B ^d  

^a HUNTINGDON LIFE SCIENCES   (United Kingdom)

^b Joan Seguer   (Spain)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

Arginine; Food preservative; LAE; Lauric acid; Safety

Indexed keywords

FOOD PRESERVATIVE; N ALPHA LAUROYLARGININE ETHYL ESTER; UNCLASSIFIED DRUG; ARGININE; DRUG DERIVATIVE; IRRITANT AGENT; N(ALPHA) LAUROYLARGININE ETHYL ESTER; N(ALPHA)-LAUROYLARGININE ETHYL ESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET; EMBRYO; EYE IRRITATION; FEEDING; FEMALE; FETUS; FOOD INTAKE; GENOTOXICITY; HYDROLYSIS; MALE; MUTAGENICITY; NEUROTOXICITY; NONHUMAN; RAT; SKIN IRRITATION; TOXICOKINETICS; UREA CYCLE; ANIMAL; DIGESTIVE TRACT INTUBATION; DOSE RESPONSE; DRUG EFFECT; INTRADERMAL DRUG ADMINISTRATION; LD 50; MUTAGEN TESTING; ORAL DRUG ADMINISTRATION; PREGNANCY; RABBIT; SALMONELLA TYPHIMURIUM; SKIN;

MAMMALIA; ORYCTOLAGUS CUNICULUS;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ANIMALS; ARGININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; FOOD PRESERVATIVES; INTUBATION, GASTROINTESTINAL; IRRITANTS; LETHAL DOSE 50; MALE; MUTAGENICITY TESTS; PREGNANCY; RABBITS; RATS; SALMONELLA TYPHIMURIUM; SKIN;

EID: 1542545026     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2003.08.022     Document Type: Article

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