Effect of the absorption enhancer saponin on the intrarenal distribution of 5-fluorouracil following its kidney surface application in rats

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 7, 2003, Pages 1049-1051

  Nakamura, Junzo ^a   Horimoto, Tomomi ^a   Hirayama, Ryu ^a   Mukai, Takahiro ^a   Nakashima, Mikiro ^a   Sasaki, Hitoshi ^a   Nishida, Koyo ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

5 fluorouracil; Absorption enhancer; Kidney; Rat; Saponin; Targeting

Indexed keywords

FLUOROURACIL; SAPONIN; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG EFFECT; DRUG TARGETING; KIDNEY HOMOGENATE; KIDNEY PARENCHYMA; MALE; NONHUMAN; RAT; ABSORPTION; ANIMAL; BLOOD; KIDNEY; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ABSORPTION; ANIMALS; FLUOROURACIL; KIDNEY; MALE; RATS; RATS, WISTAR; SAPONINS;

EID: 1542497656     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1049     Document Type: Article

References (11)

1. Motzer R. J., Russo P., J. Urol., 163, 408-417 (2000).
2. McArdle C. S., Lewi H., Hansell D., Kerr D. J., McKillop J., Willmott N., Br. J. Surg., 75, 132-134 (1988).
3. Kawakami S., Horimoto T., Nishida K., Hirayama R., Mukai T., Nakashima M., Sasaki H., Sakaeda T., Nakamura J., Biol. Pharm. Bull., 25, 928-930 (2002).
4. Watanabe J., Hayashi Y., Iwamoto K., Ozeki S., Chem. Pharm. Bull., 33, 1187-1194 (1985).
5. Sawai Y., Yamaoka K., Ito T., Nakagawa T., Biol. Pharm. Bull., 20, 1313-1316 (1997).
6. Yagoda A., Abi-Rached B., Petrylak D., Semin. Oncol., 22, 42-60 (1995).
7. Nakamura J., Yoshida Y., Mera K., Mukai T., Nishida K., Sasaki H., Biol. Pharm. Bull., 22, 713-715 (1999).
8. Hepp K. D., Diabetologia, 37, S108-S111 (1994).
9. Stellato T. A., Surg. Clin. North Am., 72, 997-1002 (1992).
10. Scheyer M., Zimmermann G., Surg. Endosc., 10, 501-503 (1996).
11. Kim C. Y., Kumar A., Sampath L., Sokol K., Modak S., Am. J. Kidney Dis., 39, 165-173 (2002).