Recombinant DNA approaches for the development of metabolic systems used in in vitro toxicology

Mutation Research/Reviews in Genetic Toxicology

Volumn 277, Issue 3, 1992, Pages 251-275

  Langenbach, Robert ^a   Smith, P Blaise ^a   Crespi, Charles ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b Gentest Corporation   (United States)

Author keywords

Cytochrome P450 enzymes; Drug metabolizing enzymes; Genetic information transfer; Recombinant DNA approaches

Indexed keywords

CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; NITROSAMINE; POLYCYCLIC AROMATIC HYDROCARBON; RECOMBINANT DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; BACTERIUM; CELL CULTURE; GENOTOXICITY; HAMSTER; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOBLAST; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; YEAST;

ANIMAL; CELLS, CULTURED; CHO CELLS; CRICETULUS; CYTOCHROME P-450 ENZYME SYSTEM; DNA, BACTERIAL; DNA, FUNGAL; DNA, RECOMBINANT; DNA, VIRAL; ENZYME ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC VECTORS; HAMSTERS; HUMAN; MICE; MICE, INBRED C3H; MODELS, GENETIC; MUTAGENICITY TESTS; MUTAGENS; TRANSFECTION; VACCINIA VIRUS;

ANIMALIA; BACTERIA (MICROORGANISMS); CRICETINAE; MAMMALIA;

EID: 1542491248     PISSN: 01651110     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1110(92)90047-D     Document Type: Article

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