Unusual expression of the F9 gene in peripheral lymphocytes hinders investigation of F9 mRNA in hemophilia B patients

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 12, 2003, Pages 2675-2676

  Green, P M ^a   Rowley, G ^a   Giannelli, F ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 9; MESSENGER RNA; PANCRELIPASE;

GENE EXPRESSION; GENETICS; HEMOPHILIA B; HUMAN; LETTER; LYMPHOCYTE; METABOLISM;

FACTOR IX; GENE EXPRESSION; HEMOPHILIA B; HUMANS; LYMPHOCYTES; PANCRELIPASE; RNA, MESSENGER;

EID: 1542440232     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2003.0543a.x     Document Type: Letter

References (13)

1. Naylor JA, Green PM, Montandon AJ, Rizza CR, Giannelli F. Detection of three novel mutations in two haemophlia patients by rapid screening of whole essential region of factor VIII gene. Lancet 1991; 337: 635-9.
2. Roberts RG, Bobrow M, Bentley DR. Point mutations in the dystrophin gene. Proc Natl Acad Sci USA 1992; 89: 2331-5.
3. Naylor JA, Green PM, Rizza CR, Giannelli F. Factor VIII gene explains all cases of haemophilia A. Lancet 1992; 340: 1066-7.
4. Naylor JA, Brinke A, Hassock S, Green PM, Giannelli F. Characteristic mRNA abnormality found in half the patients with severe haemophilia A is due to large DNA inversions. Hum Mol Genet 1993; 2: 1773-8.
5. Bagnall RD, Waseem N, Green PM, Giannelli F. Recurrent inversion breaking intron 1 of the factor VIII gene is a frequent cause of severe hemophilia A. Blood 2002; 99: 168-74.
6. Bagnall RD, Waseem NH, Green PM, Colvin B, Lee C, Giannelli F. Creation of a novel donor splice site in intron 1 of the factor VIII gene leads to activation of a 191 bp cryptic exon in two haemophilia A patients. Br J Haematol 1999; 107: 766-71.
7. Saad S, Rowley G, Tagliavacca L, Green PM, Giannelli F. UK Haemophilia Centres. First report on UK database of haemophilia B mutations and pedigrees. Thromb Haemost 1994; 71: 563-70.
8. Anagnostopoulos T, Morris AP, Ayres KL, Giannelli F, Green PM. DNA variation in a 13 Mb region including the F9 gene: inferring the genealogical history and causal role of a hemophilia B mutation (IVS 5+13 AG). J Thromb Haemost 2003; 1: 2609-14.
9. Sarkar G, Sommer SS. Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity. Science 1989; 244: 331-4.
10. Chan V, Au P, Lau P, Chan TK. A novel haemophilia B defect due to partial duplication ofthe factor IX gene. Br J Haematol 1994; 86: 601-9.
11. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem 1987; 162: 156-9.
12. Waseem NH, Bagnall R, Green PM, Giannelli F. Start of UK confidential haemophilia A database: analysis of 142patients by solid phase fluorescent chemical cleavage of mismatch. Haemophilia Centres Thromb Haemost 1998; 81: 900-5.
13. Maruyama IN, Rakow TL, Maruyama HI. cRACE. a simple method for identification of the 5' endofmRNAs. NuclAcidsRes 1995; 23: 3796-7.