Frontalin: A chemical message of musth in Asian elephants (Elephas maximus)

Chemical Senses

Volumn 28, Issue 5, 2003, Pages 433-446

  Rasmussen, L E L ^a   Greenwood, David R ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED   (New Zealand)

Author keywords

1,5 dimethyl 6,8 dioxabicyclo 3.2.1 octane; Chemical senses; Female elephant behavior; Male elephant behavior; Pheromone; Temporal gland

Indexed keywords

FRONTALIN; PHEROMONE; BUFFER; FUSED HETEROCYCLIC RINGS;

AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ASIAN; AVOIDANCE BEHAVIOR; BIOASSAY; BREATHING; BREEDING; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ELEPHANT; FEMALE; FOLLICULAR PHASE; FREQUENCY ANALYSIS; HORMONAL REGULATION; LUTEAL PHASE; MALE; MATING; NONHUMAN; ODOR; PRIORITY JOURNAL; REPRODUCTION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; URINE; ANIMAL; ASIA; DRUG EFFECT; PHYSIOLOGY; PREGNANCY; SEXUAL BEHAVIOR; SEXUAL DEVELOPMENT;

ELEPHANT; ELEPHANTIDAE; ELEPHAS MAXIMUS; HEXAPODA;

AGING; ANIMALS; ASIA; BEHAVIOR, ANIMAL; BICYCLO COMPOUNDS, HETEROCYCLIC; BUFFERS; ELEPHANTS; FEMALE; MALE; PHEROMONES; PREGNANCY; SEX CHARACTERISTICS; SEXUAL BEHAVIOR, ANIMAL; SMELL;

EID: 1542437325     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/28.5.433     Document Type: Article

References (40)

1. Francke, W., Bartels, J., Meyer, H., Schroder, F., Kohnle, U., Baader, E. and Vite, J.P. (1995) Semiochemicals from bark beetles: new results, remarks and reflections. J. Chem. Ecol., 21, 1043-1063.
2. Hess, D.L., Schmidt, A.M. and Schmidt, M.J. (1983) Reproductive cycle of the Asian elephant (Elephas maximus) in captivity. Biol. Reprod., 28, 767-773.
3. Hildebrandt, TB., Hermes, R., Pratt, N.C., Fritsch, G., Blottner, S., Schmitt, D., Ratanakorn, P, Brown, J., Rietschel, W. and Goritz, F. (2000) Ultrasonography of the urogenital tract in elephants (Loxodonta africana and Elephas maximus): an important tool for assessing male reproductive function. Zoo Biol., 19, 333-346.
4. Jainudeen, M.R., Katongole, C.B. and Short, R.V. (1972a) Plasma testosterone levels in relation to musth and sexual activity in the male Asiatic elephant, Elephas maximus. J. Reprod. Fertil., 29, 99-103.
5. Jainudeen, M.R., McKay, G.M. and Eisenberg, J.F. (1972b) Observations on musth in the domesticated Asiatic elephant, Elephas maximus. Mammalia, 36, 247-261.
6. Jemiolo, B., Xie, T.M. and Novotny, M. (1991) Socio-sexual olfactory preference in female mice: attactiveness of synthetic chemosignals. Physiol. Behav., 50, 1119-1122.
7. Kinzer, G.W., Fentiman, A.F., Jr, Page, T.F., Jr, Foltz, R.L., Vité, J.P. and Pitman, G.B. (1969) Bark beetle attractants: identification, synthesis and field bioassay of a new compound isolated from Dendroctonus. Nature, 221, 447-448.
8. Lazar, J. (2001) Elephant sex pheromone transport and recognition. Ph.D. Dissertation, University of Utah, Salt Lake City, Utah, U.S.A.
9. Lazar, J., Greenwood, D.R., Rasmussen, L.E.L. and Prestwich, G.D. (2001) Why do odorant binding proteins bind odorants? Chem. Senses, 26, 1072.
10. Lazar, J., Greenwood, D.R., Rasmussen, L.E.L. and Prestwich, G.D. (2002) Molecular and functional characterization of an odorant binding protein of the Asian elephant, Elephas maximus: implications for the role of lipocalins in mammalian olfaction. Biochemistry, 41, 11786-11794.
11. Lindgren, B.S. (1992) Attraction of Douglas-fir beetle, spruce beetle and a bark beetle predator (Coleoptera: Scolytidae and Cleridae) to enantiomers of frontalin. J. Entomol. Soc. Brit. Columb., 89, 13-17.
12. McKay, G.M. (1973) The ecology and behavior of the Asiatic elephant in southeast Ceylon. Smith. Contrib. Zool., 125, 1-113.
13. Meredith, M.L. (2000) Human vomeronasal organ function: a critical review of best and worst cases. Chem. Senses, 26, 433-446.
14. Nath, C. (1999) Health and sexual signals of male Asian elephants (Elephas maximus) in Nagarhole National Park, South India. Master's Thesis, Wildlife Institute of India, Dehradun, India.
15. Novotny, M., Harvey, S., Jemiolo, B. and Alberts, J. (1985) Synthetic pheromones that promote inter-male aggression in mice. Proc. Natl. Acad. Sci. U.S.A., 82, 2059-2061.
16. Novotny, M., Harvey, S. and Jemiolo, B. (1990) Chemistry of male dominance in the house mouse, Mus domesticus. Experientia, 46, 109-113.
17. Perrin, T.E. and Rasmussen, L.E.L. (1994) Chemosensory responses of female Asian elephants (Elephas maximus) to cyclohexanone. J. Chem. Ecol., 20, 2577-2586.
18. Perrin, T.E., Rasmussen, L.E.L., Gunawardena, R. and Rasmussen, R.A. (1996) A method for collection, long-term storage, and bioassay of labile volatile chemosignals. J. Chem. Ecol., 21, 207-221.
19. Phillips, T.W., Nation, J.L., Wilkinson, R.C., Foltz, J.L.. Pierce, H.D., Jr and Oehlschlager, A.C. (1990) Response specificity of Dendroctonus terebrans (Coleoptera: Scolytidae) to enantiomers of its sex pheromones. Ann. Entomol. Soc. Am., 83, 251-257.
20. Rasmussen, L.E.L. (1995) Evidence for the long-term chemical memory in elephants. Chem. Senses, 20, 762.
21. Rasmussen, L.E.L (1998) Chemical communication: an integral part of functional Asian elephant (Elephas maximus) society. Ecoscience, 5, 410-426.
22. Rasmussen, L.E.L. (1999a) Evolution of chemical signals in the Asian elephant, Elephas maximus: behavioral and ecological influences. J. Biosci., 24,241-251.
23. Rasmussen, L.E.L. (1999b) Elephant olfaction. ChemoSenses, 2, 4-5.
24. Rasmussen, L.E.L. and Krishnamurthy, V. (2000) How chemical signals integrate Asian elephant society: the known and the unknown. Zoo Biol., 19, 405-423.
25. Rasmussen, L.E.L. and Perrin, T.E. (1999) Physiological correlates of musth: lipid metabolites and chemosignal composition of exudates. Physiol. Behav., 67, 539-549.
26. Rasmussen, L.E.L. and Schulte, B.A. (1998) Chemical signals in the reproduction of Asian (Elephas maximus) and African (Loxodonta africana) elephants. Anim. Reprod. Sci., 53, 19-34.
27. Rasmussen, L.E., Schmidt, M.J., Henneous, R., Groves, D. and Daves, G.D., Jr (1982) Asian bull elephants: flehmen-like responses to extractable components in female elephant estrous urine. Science, 271, 159-162.
28. Rasmussen, L.E., Buss, I.O., Hess, D.L. and Schmidt, M.J. (1984) Chemical analysis of temporal gland secretions collected from an Asian bull elephant during a four-month musth episode. J. Chem. Ecol., 16, 2167-2181.
29. Rasmussen, L.E., Schmidt, M.J. and Daves, G.D. (1986) Chemical communication among Asian elephants. In Duvall, D., Muller-Schwarze, D. and Silverstein, R. (eds), Chemical Signals in Vertebrates IV. Plenum Press, New York, pp. 627-645.
30. Rasmussen, L.E.L., Lee, T.D., Roelofs, W.L., Zhang, A. and Daves, G.D., Jr (1996) Insect pheromone in elephants. Nature, 379, 684.
31. Rasmussen, L.E.L., Lee, T.D., Zhang, A., Roelofs, W.L. and Daves, G.D., Jr (1997) Purification, identification, concentration and bioactivity of (Z)-7-dodecen-1-yl acetate: sex pheromone of the female Asian elephant, Elephas maximus. Chem. Senses, 22, 417-437.
32. Rasmussen, L.E.L., Lazar, J., Greenwood, D., Feng, L. and Prestwich, G.D. (1998) Initial characterizations of secreted proteins from Asian elephants that bind the sex pheromone, (Z)-7-dodecenyl acetate. Chem. Senses, 23, 591-162.
33. Rasmussen, L.E.L., Greenwood, D.R., Lazar, J. and Prestwich, G.D. (2001) Albumin: an ideal pheromone carrier protein. Chem. Senses, 26, 1102.
34. Rasmussen, L.E.L., Riddle, H. and Krishnamurthy, V. (2002) Mellifluous matures to malodorous in musth. Nature, 415, 975-976.
35. Resko, J.A., Malley, A., Begley, D. and Hess, D.L. (1973) Radioimmunoassay of testosterone during fetal development of the rhesus monkey. Endocrinology, 93, 156-161.
36. Resko, J.A., Ellinwood, W.E., Paszter, L.M. and Buhl, A.E. (1980) Sex steroids in the umbilical circulation of fetal rhesus monkeys from the time of gonadal differentiation. J. Clin. Endocrinol. Metab., 50, 900-907.
37. Schulte, B.A. and Rasmussen, L.E.L. (1999) Signal-receiver interplay in the communication of male condition by Asian elephants. Anim. Behav., 57, 1265-1274.
38. Slade, B.E. (1999) Chemical communication of estrous cycle status and change in social behaviors with reproductive state in captive female Asian elephants, Elephas maximus. Master's Thesis, Portland State University, Portland, Oregon, USA.
39. Slade, B.E., Schulte, B.A. and Rasmussen, L.E.L. (2003) Oestrous state dynamics in chemical communication by captive female Asian elephants. Anim. Behav., 65, 813-819.
40. Sukumar, R. (1989) The Asian Elephant. Cambridge University Press, Cambridge, UK.