Biomolecular Markers and Involution of Hemangiomas

Journal of Pediatric Surgery

Volumn 39, Issue 3, 2004, Pages 400-404

  Frischer, Jason S ^a,b   Huang, Jianzhong ^a,b   Serur, Anna ^a,b   Kadenhe, Angela ^a,b   Yamashiro, Darrell J ^a,b   Kandel, Jessica J ^a,b,c  

^a Surgeons of Columbia University ^*

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c Internal Medicine New York Presbyterian   (United States)

Author keywords

Hemangioma; Hepatic angiosarcoma; Lymphatic malformation; Placental growth factor; Rapidly involuting congenital hemangioma (RICH); Vascular endothelial growth factor

Indexed keywords

ALPHA ACTIN; ANGIOPOIETIN; ANGIOPOIETIN 1; BIOLOGICAL MARKER; CD31 ANTIGEN; GROWTH FACTOR; HISTONE H3; PLACENTAL GROWTH FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANGIOMA; ANGIOSARCOMA; APOPTOSIS; BLOOD VESSEL; CELL PROLIFERATION; CELL STRUCTURE; CLINICAL ARTICLE; CONFERENCE PAPER; CONGENITAL BLOOD VESSEL MALFORMATION; CONGENITAL MALFORMATION; CONTROLLED STUDY; DISEASE MARKER; HEMANGIOMA; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INFANT; INVOLUTION; LIVER TUMOR; LYMPHATIC MALFORMATION; LYMPHATIC SYSTEM DISEASE; MALIGNANT TRANSFORMATION; NEWBORN; NICK END LABELING; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION; VASCULAR ENDOTHELIUM;

EID: 1542408730     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2003.11.043     Document Type: Conference Paper

References (21)

1. Mulliken JB, Glowacki J: Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics. Plast Reconstr Surg 69:412-422, 1982
2. Enjolras O, Mulliken JB, Boon LM, et al: Noninvoluting congenital hemangioma: A rare cutaneuos vascular anomaly. Plast Reconstr Surg 107:1647-1654, 2001
3. Enjolras O, Mulliken JB: The current management of vascular birthmarks. Pediatr Dermatol 10:311-313, 1993
4. Low DW: Hemangiomas and vascular malformations. Semin Pediatr Surg 3:40-61, 1994
5. Fishman SI, Mulliken JB: Hemangiomas and vascular malformations of infancy and childhood. Pediatr Clin North Am 40:1177-1200, 1993
6. Kirchner SG, Heller RM, Kasselberg AG, et al: Infantile hepatic hemangioendothelioma with subsequent malignant degeneration. Pediatr Radiol 11:42-45, 1981
7. Awan S, Davenport M, Portmann B, et al: Angiosarcoma of the liver in children. J Pediatr Surg 31:1729-1732, 1996
8. Razon MJ, Kraling BM, Mulliken JB, et al: Increased apoptosis coincides with onset of involution in infantile hemangioma. Microcirculation 5:189-195, 1998
9. Takahashi K, Mulliken JB, Kozakewich HP, et al: Cellular markers that distinguish the phases of hemangioma during infancy and childhood. J Clin Invest 93:2357-2364, 1994
10. Yancopoulos GD, Davis S, Gale NW, et al: Vascular-specific growth factors and blood vessel formation. Nature 407:242-248, 2000
11. Park JE, Chen HH, Winer J, et al: Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-I but not to Flk-I/KDR. J Biol Chem 269:25646-25654, 1994
12. Eriksson A, Cao R, Pawliuk R, et al: Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PIGF-I/VEGF heterodimers. Cancer Cell 1:99-108, 2002
13. Holash J, Maisonpierre PC, Compton D, et al: Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 284:1994-1998, 1999
14. Papapetropoulos A, Garcia-Cardena G, Dengler TJ, et al: Direct actions of angiopoietin-I on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab Invest 79:213-223, 1999
15. Benjamin LE, Hemo I, Keshet E: A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125:1591-1598, 1998
16. Benjamin LE, Golijanin D, Itin A, et al: Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 103:159-165, 1999
17. Joukov V, Pajusola K, Kaipainen A, et al: A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. Embo J 15:290-298, 1996
18. Ziche M, Maglione D, Ribatti D, et al: Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Invest 76:517-31, 1997
19. Viglietto G, Maglione D, Rambaldi M, et al: Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PIGF) associated with malignancy in human thyroid tumors and cell lines. Oncogene 11:1569-1579, 1995
20. Viglietto G, Romano A, Maglione D, et al: Neovascularization in human germ cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor. Oncogene 13:577-587, 1996
21. Nomura M, Yamagishi S, Harada S, et al: Placenta growth factor (PIGF) mRNA expression in brain tumors. J Neurooncol 40:123-130, 1998