Genomic organization and promoter analysis of the gene encoding the mouse chemoattractant-like receptor, CMKLR1

Gene

Volumn 328, Issue 1-2, 2004, Pages 167-176

  Mårtensson, Ulrika E A ^a   Owman, Christer ^a   Olde, Björn ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Activator protein 4; AP 4; C EBP; Ccaat enhancer binding protein; cDNA; GATA 1; GATA 2; GATA binding factor 1; GATA binding factor 2; Luciferase reporter gene; Orphan G protein coupled receptor; Sp1; Stimulating protein 1; Transcriptional regulation

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; CCAAT BINDING FACTOR; CHEMOATTRACTANT LIKE RECEPTOR 1; G PROTEIN COUPLED RECEPTOR; LUCIFERASE; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; DNA FLANKING REGION; EXON; FIBROBLAST; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENOMICS; INTRON; MOLECULAR CLONING; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TATA BOX; TRANSCRIPTION INITIATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENES; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION INITIATION SITE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 1542395658     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.12.004     Document Type: Article

References (18)

1. Andrews N.C., Faller D.V. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19:1991;2499.
2. Bouwman P., Philipsen S. Regulation of the activity of Sp1-related transcription factors. Mol. Cell. Endocrinol. 195:2002;27-38.
3. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
4. Deng H., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M., Di Marzio P., Marmon S., Sutton R.E., Hill C.M., Davis C.B., Peiper S.C., Schall T.J., Littman D.R., Landau N.R. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 381:1996;661-666.
5. Gantz I., Konda Y., Yang Y.K., Miller D.E., Dierick H.A., Yamada T. Molecular cloning of a novel receptor (CMKLR1) with homology to the chemotactic factor receptors. Cytogenet. Cell Genet. 74:1996;286-290.
6. Goodrich J.A., Cutler G., Tjian R. Contacts in context: promoter specificity and macromolecular interactions in transcription. Cell. 84:1996;825-830.
7. Heinemeyer T., Chen X., Karas H., Kel A.E., Kel O.V., Liebich I., Meinhardt T., Reuter I., Schacherer F., Wingender E. Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms. Nucleic Acids Res. 27:1999;318-322.
8. Henikoff S. Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene. 28:1984;351-359.
9. Kissonerghis M., Daly G., Feldmann M., Chernajovsky Y. The murine p75 TNF receptor promoter region: DNA sequence and characterization of a cis-acting silencer. Mol. Immunol. 36:1999;125-134.
10. Lo K., Smale S.T. Generality of a functional initiator consensus sequence. Gene. 182:1996;13-22.
11. Methner A., Hermey G., Schinke B., Hermans-Borgmeyer I. A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development. Biochem. Biophys. Res. Commun. 233:1997;336-342.
12. Murphy P.M. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12:1994;593-633.
13. Owman C., Lolait S.J., Santén S., Olde B. Molecular cloning and tissue distribution of cDNA encoding a novel chemoattractant-like receptor. Biochem. Biophys. Res. Commun. 241:1997;390-394.
14. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Plainview, NY.
15. Samson M., Edinger A.L., Stordeur P., Rucker J., Verhasselt V., Sharron M., Govaerts C., Mollereau C., Vassart G., Doms R.W., Parmentier M. ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains. Eur. J. Immunol. 28:1998;1689-1700.
16. Smale S.T., Baltimore D. The "initiator" as a transcription control element. Cell. 57:1989;103-113.
17. Suske G. The Sp-family of transcription factors. Gene. 238:1999;291-300.
18. Watson S., Arkinstall S. The G-protein Linked Receptor Facts Book. 1994;Academic press, London.