Clinical Presentation Correlates with the Type of Mismatch Repair Gene Involved in Hereditary Nonpolyposis Colon Cancer [3]

Gastroenterology

Volumn 126, Issue 3, 2004, Pages 936-937

  Bandipalliam, Prathap ^a   Garber, Judy ^a   Syngal, Sapna ^b   Kolodner, Richard D ^c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

BLOOD SAMPLING; CANCER RISK; COHORT ANALYSIS; COLORECTAL CANCER; FAMILY STUDY; GENE; GENE MUTATION; HUMAN; LETTER; MAJOR CLINICAL STUDY; MISMATCH REPAIR; MLH1 GENE; MSH2 GENE; PRIORITY JOURNAL;

EID: 1542377400     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2004.01.038     Document Type: Letter

References (5)

1. Lin KM, Shashidharan M, Thorson AG, Ternent CA, Blatchford GJ, Christensen MA, Watson P, Lemon SJ, Franklin B, Karr B, Lynch J, Lynch HT. Cumulative incidence of colorectal and extracolonic cancers in MLH1 and MSH2 mutation carriers of hereditary nonpolyposis colorectal cancer. J Gastrointest Surg 1998;2:67-71.
2. Vasen HF, Stormorken A, Menko FH, Nagengast FM, Kleibeuker JH, Griffioen G, Taal BG, Moller P, Wijnen JT. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families. J Clin Oncol 2001;19:4074-4080.
3. Syngal S, Fox EA, Li C, Dovidio M, Eng C, Kolodner RD, Garber JE. Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. JAMA 1999;282:247-253.
4. Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res 2002;62:3485-3492.
5. Lynch HT, Kimberling W, Albano WA, Lynch JF, Biscone K, Schuelke GS, Sandberg AA, Lipkin M, Deschner EE, Mikol YB, Elston RC, Bailey-Wilson JE, Danes BS. Hereditary nonpolyposis colorectal cancer (Lynch syndrome I and II). I. Clinical description of resource. Cancer 1985;56:934-938.