Antioxidative effect of propofol during cardiopulmonary bypass in adults

Acta Pharmacologica Sinica

Volumn 25, Issue 3, 2004, Pages 334-340

  Zhang, Shi Hai ^a   Wang, Shou Yong ^a   Yao, Shang Long ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cardiopulmonary bypass; Complement 5a; F2 isoprostanes; Free radicals; Propofol

Indexed keywords

ANTICOAGULANT AGENT; COMPLEMENT COMPONENT C5A; DIAZEPAM; ENFLURANE; FENTANYL; FREE RADICAL; HEPARIN; INDOMETACIN; INHALATION ANESTHETIC AGENT; INTRAVENOUS ANESTHETIC AGENT; ISOPROSTANE; ISOPROSTANE F2; MUSCLE RELAXANT AGENT; PROPOFOL; PROSTAGLANDIN F2; PROSTAGLANDIN SYNTHASE INHIBITOR; SCOPOLAMINE; UNCLASSIFIED DRUG; VECURONIUM;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLEMENT SYSTEM; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; GENERAL ANESTHESIA; HEART SURGERY; HUMAN; HUMAN CELL; INTRAVENOUS ANESTHESIA; LEUKOCYTE ADHERENCE; NEUTROPHIL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANESTHETICS, INTRAVENOUS; CARDIOPULMONARY BYPASS; CELL ADHESION; COMPLEMENT C5A; F2-ISOPROSTANES; FEMALE; FENTANYL; FREE RADICAL SCAVENGERS; HUMANS; MALE; MIDDLE AGED; NEUTROPHILS; PROPOFOL;

EID: 1542374052     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Cavarocchi NC, England MD, Schaff HV, Russo P, Orszulak TA, Schnell WA Jr, et al. Oxygen free radical generation during cardiopulmonary bypass: correlation with complement activation. Circulation 1986; 74 (suppl): III 130-3.
2. Nakaya H, Tohse N, Kanno M. Electrophysiological derangements induced by lipid peroxidation in cardiac tissue. Am J Physiol 1987; 253: H1089-97.
3. Webster NR, Nunn JF. Molecular structure of free radicals and their importance in biological reactions. Br J Anaesth 1988; 60: 98-108.
4. Navapurkar VU, Skepper JN, Jones JG, Menon DK. Propofol preserves the viability of isolated rat hepatocyte suspensions under an oxidant stress. Anesth Analg 1998; 87: 1152-7.
5. 2-like compounds are produced in vivo in humans by a noncyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 1990; 87: 9383-7.
6. 2-isoprostanes) in carbon tetrachloride hepatotoxicity: an animal model of lipid peroxidation. J Clin Invest 1992; 90: 2502-7.
7. Prasad K, Kalra J, Bharadwaj B, Chaudhary A. Increased oxygen free radical activity in patients on cardiopulmonary bypass undergoing aortocoronary bypass surgery. Am Heart J 1992; 123: 37-45.
8. Fantone JC, Ward PA. Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reaction. Am J Pathol 1982; 47: 397-417.
9. Morrow JD, Frei B, Longmire AW, Gaziano JM, Lynch SM, Shyr Y, et al. Increase in circulating products of lipid peroxidation (F2-Isoprostanes) in smokers - smoking as a cause of oxidative damage. N Engl J Med 1995; 332: 1198-203.
10. 2-isoprostanes. Clin Chem 2001; 47: 1306-8.
11. 2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism. Methods Enzymol 1994; 233: 163-74.
12. Suzuki Y, Nishio K, Takeshita K, Takeuchi O, Watanabe K, Sato N, et al. Effect of steroid on hyperoxia-induced ICAM-1 expression in pulmonary endothelia cells. Am J Physiol Lung Cell Mol Physiol 2000; 278: L245-52.
13. Murphy PG, Davies MJ, Columb MO, Stratford N. Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte. Br J Anaesth 1996; 76: 536-43.
14. Davies SW, Duffy JP, Wickens DG, Underwood SM, Hill A, Alladine MF, et al. Cardiopulmonary bypass, myocardial management, and support techniques: time-course of free radical activity during coronary artery operations with cardiopulmonary bypass. J Thorac Cardiovasc Surg 1993; 105: 979-87.
15. McIntyre TM, Zimmerman GA, Prescott SM. Biologically active oxidized phospholipids. J Biol Chem 1999; 274: 25189-92.
16. Hess ML, Manson NH. Molecular oxygen: Friend and foe. The role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury. J Mol Cell Cardiol 1984; 16: 969-85.
17. Corretti MC, Koretsune Y, Kusuoka H, Chacko VP, Zweier JL, Marban E. Glycolytic inhibition and calcium overload as consequences of endogenously generated free radicals in rabbit hearts. J Clin Invest 1991; 88: 1014-25.
18. Cook DJ, Housmans PR. Mechanism of the negative inotropic effect of propofol in isolated ferret ventricular myocardium. Anesthesiology 1994; 80: 859-71.
19. Green TR, Bennett SR, Nelson VM. Specificity and properties of propofol as an antioxidant free radical scavenger. Toxicol Appl Pharmacol 1994; 129: 163-9.
20. Murphy PG, Bennett JR, Meyers DS, Davies MJ, Jones JG. The effect of propofol anaesthesia on free radical-induced lipid peroxidation in rat liver microsomes. Eur J Anaesthesiol 1993; 10: 261-6.
21. Chenoweth DE, Hugli TE. Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes. Proc Natl Acad Sci USA 1978; 75: 3943-7.
22. Kirklin JK, Westaby S, Blackstone EH, Kirklin JW, Chenoweth DE, Pacifico AD. Complement and the damaging effects of cardiopulmonary bypass. J Thorac Cardiovasc Surg 1983; 86: 845-57.
23. Vertrees R, Tao W, Kramer GC, Nutt L, McDaniel LB, DeVine SD, et al. Tumor necrosis factor monoclonal antibody prevents alteration in leucocyte population during cardiopulmonary bypass. ASAIO J 1994; 40: M554-9.
24. Mikawa K, Akamatsu H, Nishina K, Shiga M, Maekawa N, Obara H, et al. Propofol inhibits human neutrophil functions. Anesth Analg 1998; 87: 695-700.
25. Hall RI, Smith MS, Rocker G. The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations. Anesth Analg 1997; 85: 766-82.
26. Rashid MA, William-Olsson G. Are leukocytosis and lipid peroxidation involved in ischemic or reperfusion injury in cardiac surgery? Thorac Cardiovasc Surg 1991; 39: 193-5.