Simultaneous Quantification of Doxorubicin, Lorazepam, Metoclopramide, Ondansetron, and Ranitidine in Mixtures by Liquid Chromatography-Tandem Mass Spectrometry

Journal of Liquid Chromatography and Related Technologies

Volumn 27, Issue 4, 2004, Pages 641-660

  Abdel Hamid, Mohammed E ^a   Sharma, Deepa ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Doxorubicin; LC MS MS; Lorazepam; Metoclopramide; Ondansetron; Ranitidine

Indexed keywords

CONCENTRATION (PROCESS); IONIZATION; MASS SPECTROMETRY; METHANOL; MIXTURES;

CO-ADMIXED COMPOUNDS;

LIQUID CHROMATOGRAPHY;

4 PHENYL 4 AMINOBUTANOIC ACID; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; BUTYRIC ACID DERIVATIVE; DOXORUBICIN; FORMIC ACID; LORAZEPAM; METOCLOPRAMIDE; ONDANSETRON; RANITIDINE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CALIBRATION; DRUG DETERMINATION; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; QUANTITATIVE ASSAY; STANDARD; TANDEM MASS SPECTROMETRY;

EMESIS;

EID: 1542374023     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-120028254     Document Type: Article

References (12)

1. Zhang, H.L.; Ye, L.; Stewart, J.T. HPLC determinations of doxorubicin with selected medications in 0.9% sodium chloride injection USP. J. Liq. Chromatogr. & Rel. Technol. 1998, 21, 2375-2385.
2. King, D.T.; Venkateshwaran, T.G.; Stewart, J.T. HPLC determination of a vincristine, doxorubicin and ondansetron mixture in 0.9% sodium chloride injection. J. Liq. Chromatogr. 1994, 17, 1399-1411.
3. Perez-Ruiz, T.; Martinez-Lozano, C.; Sanz, A.; Bravo, E. Simultaneous determination of doxorubicin, daunorubicin and idarubicin by capillary electrophoresis with laser-induced, fluorescence detection. Electrophoresis 2001, 22, 134-138.
4. Venkateshwaran, T.G.; King, D.T.; Stewart, J.T. HPLC determination of ondansetron-atropine and ondansetron-glycopyrrolate mixtures in 0.9% sodium chloride injection. J. Liq. Chromatogr. 1995, 18, 2647-2659.
5. Venkateshwaran, T.G. King D.T. Stewart, J.T. HPLC determination of a metocloptamide and ondansetron mixture in 0.9% sodium chloride injection. J. Liq. Chromatogr. 1995, 18, 117-126.
6. Ye, L.; Stewart, J.T. HPLC determination of an ondansetron and diphenhydramine mixture in 0.9% sodium chloride injection. J. Liq. Chromatogr. & Rel. Technol. 1996, 19, 711-718.
7. Venkateshwaran, T.G.; Stewart, J.T.; King, D.T. HPLC determinations of ondansetron with selected medications in 0.9% sodium chloride injection USP. J. Liq. Chromatogr. & Rel. Technol. 1996, 19, 3355-3367.
8. Niessen, W.M.A. Liquid Chromatography-Mass Spectrometry, 2nd Ed.; Marcel Dekker: New York, 1998; 405.
9. Voyksner, R.D. Electrospray Ionization Mass Spectrometry; Fundamentals, Instrumentation and Applications; Cole, R.B., Ed.; Wiley Interscience: New York, 1997; 323.
10. Lachatre, F.; Marquet, P.; Ragot, S.; Gaulier, J.M.; Cardot, P.; Dupuy, J.L. Simultaneous determination of four anthracyclines and three metabolites in human serum by liquid chromatography-electrospray mass spectrometry. J. Chromatogr. B-Biomed. Appl. 2000, 738, 281-291.
11. Abdel-Hamid, M.E.; Phillips, O.A. LC-MS/MS determination of carbamazepine, pindolol and theophylline in human serum. J. Liq. Chromatogr. & Rel. Technol. 2003, 26, 1927-1947.
12. R injections. J. Pharm. Biomed. Anal. 2003, 32, 1167-1174.