An evaluation of the moisturizing and anti-itch effects of a lactic acid and pramoxine hydrochloride cream

Cutis

Volumn 73, Issue 2, 2004, Pages 135-139

  Grove, Gary ^a   Zerweck, Charles ^b  

^a Skin Study Center   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPRURITIC AGENT; LACTIC ACID; PRAMOCAINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DRUG EFFICACY; DRUG TOLERABILITY; DRY SKIN; ECZEMA; FEMALE; HUMAN; HUMIDIFIER; OPEN STUDY; PRURITUS; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; STATISTICAL SIGNIFICANCE; WINTER;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; ANTIPRURITICS; DRUG COMBINATIONS; FEMALE; GALVANIC SKIN RESPONSE; HUMANS; HUMIDITY; LACTIC ACID; MIDDLE AGED; MORPHOLINES; OINTMENTS; PRURITUS; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; TREATMENT OUTCOME;

EID: 1542373574     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Lawley TJ, Swerlick RA. Eczema, psoriasis, cutaneous infections, acne and other common skin disorders. In: Wilson JD, Braunwald E, Isselbacher KJ, et al, eds. Harrison's Principles of Internal Medicine. 12th ed. New York, NY: McGraw-Hill, Inc; 1991:307-312.
2. Jennings MB, Logan L, Alfieri DM, et al. A comparative study of lactic acid 10% and ammonium lactate 12% lotion in the treatment of foot xerosis. J Am Podiatr Med Assoc. 2002;92:143-148.
3. Wehr R, Krochmal L, Bagatell F, et al. A controlled two-center study of lactic acid 12 percent lotion and a petrolatum-based crème in patients with xerosis. Cutis. 1986;37:205-207, 209.
4. Dahl MV, Dahl AC. 12% lactate lotion for the treatment of xerosis. a double-blind clinical evaluation. Arch Dermatol. 1983;119:27-30.
5. Kempers S, Katz HI, Wildnauer R, et al. An evaluation of the effect of an alpha hydroxy acid-blend skin cream in the cosmetic improvement of symptoms of moderate to severe xerosis, epidermolytic hyperkeratosis, and ichthyosis. Cutis. 1998;61:347-350.
6. Van Scott EJ, Yu RJ. Alpha hydroxy acids: procedures for use in clinical practice. Cutis. 1989;43:222-228.
7. Yosipovitch G, Maibach HI. Effect of topical pramoxine on experimentally induced pruritus in humans. J Am Acad Dermatol. 1997;37:278-280.
8. Fisher AA. The safety of pramoxine hydrochloride when used as a topical (surface) anesthetic. Cutis. 1998;62:122-123.
9. Grove GL. Noninvasive methods for assessing moisturizers. In: Waggoner WC, ed. Clinical Safety and Efficacy Testing of Cosmetics. New York, NY: Marcel Dekker, Inc; 1990:121-148.
10. Grove GL. The effect of moisturizers on skin surface hydration as measured in vivo by electrical conductivity. Curr Ther Res. 1991;50:712-719.
11. Grove GL. Skin surface hydration changes during a mini regression test as measured in vivo by electrical conductivity. Curr Ther Res. 1992;52:556-561.