Modeling of Electro-Mechanics of Human Cardiac Myocytes: Parameterization with Numerical Minimization Techniques

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 3, Issue , 2003, Pages 2810-2813

  Sachse, F B ^a   Seemann, G ^b   Chaisaowong, K ^b   Mohr, M B ^b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; COMPUTER SIMULATION; MATHEMATICAL MODELS; NEUROPHYSIOLOGY; OPTIMIZATION; PATHOLOGY; RUNGE KUTTA METHODS; SIGNAL DETECTION;

CARDIAC MYOCITES; CELLULAR ELECTROPHYSIOLOGY;

CARDIOVASCULAR SYSTEM;

EID: 1542360682     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (16)

1. W. H. Press, S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery, Numerical Recipes in C. Cambridge, New York, Melbourne: Cambridge University Press, 2 ed., 1992.
2. A. L. Hodgkin and A. F. Huxley, "A quantitative description of membrane current and its application to conduction and excitation in nerve," J. Physiol, vol. 177, pp. 500-544, 1952.
3. L. Priebe and D. J. Beuckelmann, "Simulation study of cellular electric properties in heart failure," Circ. Res., vol. 82, pp. 1206-1223, 1998.
4. C.-H. Luo and Y. Rudy, "A dynamic model of the ventricular cardiac action potential: I. simulations of ionic currents and concentration changes," Circ. Res., vol. 74, no. 6, pp. 1071-1096, 1994.
5. C.-H. Luo and Y. Rudy, "A dynamic model of the ventricular cardiac action potential: II. afterdepolarizations, triggered activity, and potentiation," Circ. Res., vol. 74, no. 6, pp. 1097-1113, 1994.
6. NCX is favored in failing human ventricular myocytes.," Ann. N. Y. Sci., vol. 976, pp. 478-479, 2002.
7. 2+] during the cardiac action potential," Circ. Res., vol. 90, pp. 182-189, 2001.
8. F. B. Sachse, K. Glänzel, and G. Seemann, "Modeling of protein interactions involved in cardiac tension development," IJBC, 2003. accepted for publication.
9. F. B. Sachse and G. Seemann, "Modeling of cardiac electro-mechanics in a truncated ellipsoid model of left ventricle," LNCS, 2003. accepted for publication.
10. K. Glänzel, "Kraftentwicklung im Sarkomer unter Berücksichtigung elektromechanischer Kopplung," Diploma Thesis, Institut für Biomedizinische Technik, Universität Karlsruhe (TH), Sep. 2002.
11. J. J. Rice, R. L. Winslow, and W. C. Hunter, "Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses," Am. J. Physiol. Circ. Heart., vol. 276, pp. H1734-H1754, 1999.
12. A. Gordon, M. Regnier, and E. Homsher, "Skeletal and cardiac muscle contractile activation: Tropomyosin "rocks and rolls"," News Physiol. Sci., vol. 16, pp. 49-55, 2001.
13. D. M. Bers, Excitation-Contraction Coupling and Cardiac Contractile Force. Dordrecht, Netherlands: Kluwer Academic Publishers, 1991.
14. J. A. Spudich, "TIMELINE: The myosin swinging cross-bridge model," Nature Reviews Molecular Cell Biology, vol. 2, pp. 387-392, 2001.
15. 2+] in intact human myocardium," Circ., vol. 82, pp. 1266-1278, 1990.
16. V. Piacentino III, C. R. Weber, X. Chen, J. Weisser-Thomas, K. B. Margulies, D. M. Bers, and S. R. Houser, "Cellular basis of abnormal calcium transients of failing human ventricular myocytes," Circ. Res., vol. 92, pp. 651-658, 2003.