Nuclear entry of poliovirus protease-polymerase precursor 3CD: Implications for host cell transcription shut-off

Virology

Volumn 320, Issue 2, 2004, Pages 195-205

  Sharma, Rakhi ^a   Raychaudhuri, Santanu ^a   Dasgupta, Asim ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

NLS; Poliovirus; Transcription shut off; Viral protease polymerase precursor 3CD

Indexed keywords

ENZYME PRECURSOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEINASE; RNA POLYMERASE; VIRUS ENZYME;

AMINO ACID SEQUENCE; ARTICLE; CELL FRACTIONATION; CELL NUCLEUS; CYTOPLASM; FEMALE; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; MUTAGENESIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS INFECTION;

CELL NUCLEUS; CYSTEINE ENDOPEPTIDASES; DNA-DIRECTED RNA POLYMERASES; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LUMINESCENT PROTEINS; NUCLEAR LOCALIZATION SIGNALS; POLIOVIRUS; PROTEIN PRECURSORS; PROTEINS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION, GENETIC; TRANSFECTION; VIRAL PROTEINS;

MAMMALIA; POLIOVIRUS;

EID: 1542345709     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2003.10.020     Document Type: Article

References (45)

1. Agol V.I., Belov G.A., Bienz K., Egger D., Kolesnikova M.S., Romanova L.I., Sladkova L.V., Tolskaya E.A. Competing death programs in poliovirus-infected cells: commitment switch in the middle of the infectious cycle. J. Virol. 74:2000;5534-5541.
2. Belov G.A., Evstafieva A.G., Rubtsov Y.P., Mikitas O.V., Vartapetian A.B., Agol V.I. Early alteration of nucleocytoplasmic traffic induced by some RNA viruses. Virology. 275:2000;244-248.
3. Bienz K., Egger D., Rasser Y., Bossart W. Accumulation of poliovirus proteins in the host cell nucleus. Intervirology. 18:1982;189-196.
4. Bienz K., Egger D., Rasser Y., Bossart W. Intracellular distribution of poliovirus proteins and the induction of virus-specific cytoplasmic structures. Virology. 131:1983;39-48.
5. Blair W.S., Li X., Semler B.L. A cellular cofactor facilitates efficient 3CD cleavage of the poliovirus P1 precursor. J. Virol. 67:1993;2336-2343.
6. Carrington J.C., Freed D.D., Leinicke A.J. Bipartite signal sequence mediates nuclear translocation of the plant potyviral NIa protein. Plant Cell. 3(9):1991;953-962.
7. Clark M.E., Dasgupta A. A transcriptionally active form of TFIIIC is modified in poliovirus-infected cells. Mol. Cell. Biol. 10:1990;5106-5113.
8. Clark M.E., Hammerle T., Wimmer E., Dasgupta A. Poliovirus proteinase 3C converts an active form of transcription factor IIIC to an inactive form: a mechanism for inhibition of host cell pol III transcription by poliovirus. EMBO J. 10:1991;2941-2947.
9. Clark M.E., Lieberman M., Berk A.J., Dasgupta A. Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitro. Mol. Cell. Biol. 13:1993;1232-1237.
10. Dasgupta A.et al. Semler B.L., Wimmer E. Molecular Biology of Picornaviruses. 2003;321-335 ASM press, Washington D.C.
11. Diamond S., Kirkegaard K. Clustured charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiplets mutants defective in RNA synthesis. J. Virol. 68:1994;863-876.
12. Dingwall C., Laskey R.A. Nuclear targeting sequences a consensus? Trends Biochem. Sci. 16:1991;478-491.
13. Doedens J.R., Kirkegaard K. Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14:1995;894-907.
14. Etchison D., Mulburn S.C., Edery I., Sonenberg N., Hershey J.W.B. Inhibition of Hela cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eukaryotic initiation factor 3 and a cap binding protein complex. J. Biol. Chem. 257:1982;14806-14810.
15. Falk M.M.et al. Foot-and-mouth disease virus protease 3C induces specific proteolytic cleavage of host cell histone H3. J. Virol. 64:1990;748-756.
16. Fernandez T.C. The presence of viral induced proteins in nuclei from poliovirus-infected HeLa cells. Virology. 116:1982;629-634.
17. Gradi A., Svitkin Y.V., Imataka H., Sonenberg N. Proteolysis of human translation initiation factor eIF4GII, but not eIF4GI, coincides with the shut-off of host protein synthesis after poliovirus infection. Proc. Natl. Acad. Sci. U.S.A. 95:1998;11089-11094.
18. Gustin K.E., Sarnow P. Effects of poliovirus infection on nucleo-cytoplasmic trafficking and nuclear pore complex composition. EMBO J. 20:2001;240-249.
19. Gustin K.E., Sarnow P. Inhibition of nuclear import and alteration of nuclear pore complex formation by rhinovirus. J. Virol. 76:2002;8787-8796.
20. Hansen J., Long A., Schultz S. Structure of the RNA-dependent RNA polymerase of poliovirus. Structure. 5:1997;1109-1122.
21. Harris K.S., Reddigari S.R., Nicklin M.J., Hammerle T., Wimmer E. Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase. J. Virol. 66:1992;7481-7489.
22. Hu Y., Fisette P.L., Denlinger L.C., Guadarrama A.G., Sommer J.A., Proctor R.A., Bertics P.J. Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric oxide synthase expression in RAW 264.7 macrophages. J. Biol. Chem. 273:1998;27170-27175.
23. Kaariainen L., Ranki M. Inhibition of cell functions by RNA virus infections. Annu. Rev. Microbiol. 38:1984;91-109.
24. Krausslich H., Wimmer E. Viral proteinases. Annu. Rev. Biochem. 57:1988;701-754.
25. Lawson M.A., Semler B.A. Picornavirus protein processing - Enzymes, substrates and genetic regulation. Curr. Top. Microbiol. Immunol. 161:1990;49-87.
26. Leong L.E.-C., Cornell C.T., Semler B.A. Semler B.L., Wimmer E. Molecular Biology of Picornaviruses. 2003;187-197 ASM press, Washington, D.C.
27. Li X.H., Carrington J.C. Complementation of tobacco etch potyvirus mutants by active RNA polymerase expressed in transgenic cells. Proc. Natl. Acad. Sci. U.S.A. 92:1995;457-461.
28. Li X.H., Valdez P., Olvera R.E., Carrington J.C. Functions of the tobacco etch virus RNA polymerase (NIb): subcellular transport and protein-protein interaction with VPg/proteinase (Nia). J. Virol. 71:1997;1598-1607.
29. McBride A.E., Schlegel A., Kirkegaard K. Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells. Proc. Natl. Acad. Sci. U.S.A. 93:1996;2296-2301.
30. Meerovitch K., Svitkin Y.V., Lee H.S., Lezbkowicz F., Kenan D.J., Chan E.K., Agol V.I., Keene J.D., Sonenberg N. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:1993;3798-3807.
31. Neufeld K.L., Richards O.C., Ehrenfeld E. Expression and characterization of poliovirus proteins 3BVPg, 3Cpro, and 3Dpol in recombinant baculovirus infected Spodoptera frugiperda cells. Virus Res. 19:1991;173-188.
32. Parsley T.B., Cornell C.T., Semler B.L. Modulation of the RNA binding and protein processing activities of poliovirus polypeptide 3CD by the viral RNA polymerase domain. J. Biol. Chem. 274:1999;12867-12876.
33. Rubinstein S.J., Dasgupta A. Inhibition of rRNA synthesis by poliovirus: specific inactivation of transcription factors. J. Virol. 63:1989.
34. Rubinstein S.J., Hammerle T., Wimmer E., Dasgupta A. Infection of HeLa cells with poliovirus results in modification of a complex that binds to the rRNA promoter. J. Virol. 66:1992;3062-3068.
35. Schaad M.C., Haldeman-Cahill R., Cronin S., Carrington J.C. J. Virol. 70:1996;7039-7048.
36. pro-mediated cleavage. J. Virol. 73:1999;2193-2200.
37. Suhy D.A., Giddings T.H. Jr., Kirkegaard K. Remodeling of the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J. Virol. 74:2000;8953-8965.
38. Tolskaya E.A., Romanova L.I., Kolesnikova M.S., Ivannikova T.A., Smirnova E.A., Raikhlin N.T., Agol V.I. Apoptosis-inducing and apoptosis-preventing functions of poliovirus. J. Virol. 69:1995;1181-1189.
39. Waggoner S., Sarnow P. Viral ribonucleoprotein complex formation and nucleolar-cytoplasmic relocalization of nucleolin in poliovirus infected cells. J. Virol. 72:1998;6699-6709.
40. Weidman K., Yalamanchili P., Ng B., Tsai W., Dasgupta A. Poliovirus 3C-mediated degradation of transcriptional activator p53 requires a cellular activity. Virology. 291:2001;260-271.
41. Wimmer E., Hellen C.U.T., Cao X. Genetics of poliovirus. Annu. Rev. Genet. 27:1993;353-436.
42. pro) inhibits formation of TBP-TATA box complex in vitro. J. Virol. 70:1996;2922-2929.
43. pro. J. Virol. 71:1997;1220-1226.
44. pro. Virology. 239:1997;176-185.
45. Ypma-Wong M.F., Dewalt P.G., Johnson V.H., Lamb J.G., Semler B.L. Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor. Virology. 166:1988;265-270.