HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1447-1454

  Mustata, Gabriela Iurcu ^a,c   Brigo, Alessandro ^b   Briggs, James M ^a  

^a University of Houston   (United States)

^b UNIVERSITY OF PADOVA   (Italy)

^c Emisphere Technologies Inc   (United States)

Author keywords

HIV 1 integrase; Inhibitor design; Pharmacophore model

Indexed keywords

BENZOIC ACID DERIVATIVE; BENZOIC HYDRAZIDE; COUMARIN; DEPSIDE; DEPSIDONE; DIKETONE; DIOXEPINONE; INTEGRASE; NAPHTHYRIDINE DERIVATIVE; PROTEIN INHIBITOR; QUINOLINE DERIVATIVE; QUINONE DERIVATIVE; SALICYLPYRAZOLINONE; THIAZEPINE DERIVATIVE; THIAZOLOTHIAZEPINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG ACTIVITY; DRUG STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PHARMACOPHORE; PROTEIN STRUCTURE; SCREENING; STRUCTURE ACTIVITY RELATION;

HIV INTEGRASE; HIV INTEGRASE INHIBITORS; MODELS, MOLECULAR;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 1542345402     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.027     Document Type: Article

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