Viscoelastic Behavior of Rat Cortex in Response to Micro-scale-Volume Fluid Injections

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 2, Issue , 2003, Pages 1948-1951

  Nunamaker, E A ^a   Rathnasingham, R ^a   Kipke, D R ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

BioMEMS; Drug delivery; Microfluidics; Neuroprosthesis

Indexed keywords

BRAIN; DIFFUSION; FLUIDICS; FUNCTIONAL NEURAL STIMULATION; MICROELECTRODES; MICROELECTROMECHANICAL DEVICES; NEUROPHYSIOLOGY; POROSITY; PROSTHETICS; TISSUE; VISCOELASTICITY; VOLUME MEASUREMENT;

BIOMEMS; MICROFLUIDICS; NEURONS; NEUROPROSTHESIS; POROELASTIC PROPERTIES;

CONTROLLED DRUG DELIVERY;

EID: 1542331476     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (13)

1. Rathnasingham, R., D. R. Kipke, S. C. Bledsoe, J. D. McLaren, Characterization of Implantable Microfabricated Fluid Delivery Devices. IEEE Transactions on Biomedical Engineering, In Press.
2. Leech, P. and J.D. Miller, Intracranial volume - pressure relationships during experimental brain compression in primates. 1. Pressure responses to changes in ventricular volume. J Neurol Neurosurg Psychiatry, 1974. 37(10): p. 1093-8.
3. Schettini, A. and E.K. Walsh, Brain tissue elastic behavior and experimental brain compression. Am J Physiol, 1988. 255(5 Pt 2): p. R799-805.
4. Walsh, E.K. and A. Schettini, Brain tissue elasticity and CSF elastance. Neurol Res, 1990.12(2): p. 123-7.
5. Tenti, G., J.M. Drake, and S. Sivaloganathan, Brain biomechanics: mathematical modeling of hydrocephalus. Neurol Res, 2000. 22(1): p. 19-24.
6. Nicholson, C. and E. Sykova, Extracellular space structure revealed by diffusion analysis. Trends in Neurosciences, 1998. 21(5): p. 207-15.
7. Rusakov, D.A. and D.M. Kullmann, A tortuous and viscous route to understanding diffusion in the brain. Trends in Neurosciences, 1998. 21(11): p. 469-70.
8. Rousche, P.J., et al., Flexible polyimide-based intracortical electrode arrays with bioactive capability. Ieee Transactions on Biomedical Engineering, 2001. 48(3): p. 361-371.
9. Ford, T.R., et al., Perialveolar Interstitial Resistance and Compliance in Isolated Rat Lung. Journal of Applied Physiology, 1991. 70(6): p. 2750-2756.
10. Turner J.N., et al., Cerebral astrocyte response to micromachined silicon implants. Experimental Neurology, 1999.156: p. 33-49.
11. Williams, J.C., et al. Correlation analysis of electrical interface properties of chronic neural implants, in Soc. Neurosci. Abstr. 2001. San Diego, California.
12. Chen, J., et al., A multichannel neural probe for selective chemical delivery at the cellular level. IEEE Trans Biomed Eng, 1997. 44(8): p. 760-9.
13. Rousche, P.J., et al., Flexible polyimide-based intracortical electrode arrays with bioactive capability. IEEE Trans Biomed Eng, 2001. 48(3): p. 361-71.