Characterization of the various forms of the Reelin protein in the cerebrospinal fluid of normal subjects and in neurological diseases

Neurobiology of Disease

Volumn 15, Issue 2, 2004, Pages 326-330

  Ignatova, Nina ^a   Sindic, Christian J M ^a   Goffinet, André M ^a,b  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Alzheimer's disease; Autism; Brain development; Cerebrospinal fluid; Dab1; Reelin; Schizophrenia

Indexed keywords

MONOCLONAL ANTIBODY; REELIN;

ADOLESCENT; ADULT; AGE; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CEREBROSPINAL FLUID; CHILD; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; NEUROLOGIC DISEASE; PLASMA; PRESERVATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STORAGE TEMPERATURE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; ANTIBODIES, MONOCLONAL; BRAIN; CELL ADHESION MOLECULES, NEURONAL; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; EXTRACELLULAR MATRIX PROTEINS; HUMANS; INFANT; MIDDLE AGED; NERVE TISSUE PROTEINS; NERVOUS SYSTEM DISEASES; PROTEIN STRUCTURE, TERTIARY; REFERENCE VALUES; SERINE ENDOPEPTIDASES;

EID: 1542330666     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2003.11.008     Document Type: Article

References (20)

1. Andres C. Molecular genetics and animal models in autistic disorder. Brain Res. Bull. 57:2002;109-119.
2. Bonora E., Beyer K.S., Lamb J.A., Parr J.R., Klauck S.M., Benner A., Paolucci M., Abbott A., Ragoussis I., Poustka A., Bailey A.J., Monaco A.P. Analysis of reelin as a candidate gene for autism. Mol. Psychiatry. 8:2003;885-892.
3. Brich J., Shie F.S., Howell B.W., Li R., Tus K., Wakeland E.K., Jin L.W., Mumby M., Churchill G., Herz J., Cooper J.A. Genetic modulation of tau phosphorylation in the mouse. J. Neurosci. 23:2003;187-192.
4. D'Arcangelo G., Miao G.G., Chen S.C., Soares H.D., Morgan J.I., Curran T. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature. 374:1995;719-723.
5. de Bergeyck V., Naerhuyzen B., Goffinet A.M., Lambert de Rouvroit C. A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant mice. J. Neurosci. Methods. 82:1998;17-24.
6. Fatemi S.H. The role of Reelin in pathology of autism. Mol. Psychiatry. 7:2002;919-920.
7. Guidotti A., Pesold C., Costa E. New neurochemical markers for psychosis: a working hypothesis of their operation. Neurochem. Res. 25:2000;1207-1218.
8. Hong S.E., Shugart Y.Y., Huang D.T., Shahwan S.A., Grant P.E., Hourihane J.O., Martin N.D., Walsh C.A. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations. Nat. Genet. 26:2000;93-96.
9. Jossin Y., Bar I., Ignatova N., Tissir F., De Rouvroit C.L., Goffinet A.M. The reelin signaling pathway: some recent developments. Cereb. Cortex. 13:2003;627-633.
10. Krebs M.O., Betancur C., Leroy S., Bourdel M.C., Gillberg C., Leboyer M. Absence of association between a polymorphic GGC repeat in the 5′ untranslated region of the reelin gene and autism. Mol. Psychiatry. 7:2002;801-804.
11. Lambert de Rouvroit C., Goffinet A.M. The reeler mouse as a model of brain development. Adv. Anat., Embryol. Cell Biol. 150:1998;1-106.
12. Lambert de Rouvroit C., de Bergeyck V., Cortvrindt C., Bar I., Eeckhout Y., Goffinet A.M. Reelin, the extracellular matrix protein deficient in reeler mutant mice, is processed by a metalloproteinase. Exp. Neurol. 156:1999;214-217.
13. Lugli G., Krueger J.M., Davis J.M., Persico A.M., Keller F., Smalheiser N.R. Methodological factors influencing measurement and processing of plasma reelin in humans. BMC Biochem. 4:2003;9.
14. Ogawa M., Miyata T., Nakajima K., Yagyu K., Seike M., Ikenaka K., Yamamoto H., Mikoshiba K. The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron. 14:1995;899-912.
15. Persico A.M., D'Agruma L., Maiorano N., Totaro A., Militerni R., Bravaccio C., Wassink T.H., Schneider C., Melmed R., Trillo S., Montecchi F., Palermo M., Pascucci T., Puglisi-Allegra S., Reichelt K.L., Conciatori M., Marino R., Quattrocchi C.C., Baldi A., Zelante L., Gasparini P., Keller F. Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder. Mol. Psychiatry. 6:2001;150-159.
16. Pesold C., Impagnatiello F., Pisu M.G., Uzunov D.P., Costa E., Guidotti A., Caruncho H.J. Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats. Proc. Natl. Acad. Sci. U. S. A. 95:1998;3221-3226.
17. Reiber H. Dynamics of brain-derived proteins in cerebrospinal fluid. Clin. Chim. Acta. 310:2001;173-186.
18. Rice D.S., Curran T. Role of the reelin signaling pathway in central nervous system development. Annu. Rev. Neurosci. 24:2001;1005-1039.
19. Saez-Valero J., Costell M., Sjögren M., Andreasen N., Blennow K., Luque J.M. Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer disease. J. Neurosci. Res. 2003.
20. Tissir F., Goffinet A.M. Reelin and brain development. Nat. Rev., Neurosci. 4:2003;496-505.