Agonist enhancement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus

Biochemical Pharmacology

Volumn 67, Issue 6, 2004, Pages 1019-1024

  Forrester, Sean G ^a,b   Beech, Robin N ^a   Prichard, Roger K ^a  

^a MCGILL UNIVERSITY   (Canada)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

African green monkey kidney cells; COS 7; GABA; GluCl; Glutamate gated chloride channel; Haemonchus contortus glutamate gated chloride channel subunit; HcGluCla; Ivermectin; IVM; MOX; Moxidectin; N methyl D aspartic acid; NMDA; Picrotoxin; PTX

Indexed keywords

ANTHELMINTIC AGENT; CHLORIDE CHANNEL; GLUTAMIC ACID; IBOTENIC ACID; IVERMECTIN; LIGAND; MACROCYCLIC COMPOUND; TRITIUM; GLUTAMATE GATED CHLORIDE CHANNELS; GLUTAMATE-GATED CHLORIDE CHANNELS; MACROLIDE; MILBEMYCIN; PROTEIN SUBUNIT;

AGONIST; ANIMAL CELL; ANIMAL PARASITOSIS; ANTHELMINTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG SCREENING; GERBIL; GLUTAMATE GATED CHLORIDE CHANNEL; HAEMONCHUS CONTORTUS; NEMATODE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS; ANIMAL; BINDING COMPETITION; CELL STRAIN COS1; DRUG INTERACTION; HAEMONCHUS; METABOLISM;

ANIMALS; ANTHELMINTICS; BINDING, COMPETITIVE; CHLORIDE CHANNELS; COS CELLS; DRUG INTERACTIONS; HAEMONCHUS; IBOTENIC ACID; IVERMECTIN; MACROLIDES; PROTEIN SUBUNITS; TRITIUM;

EID: 1542330617     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2003.08.047     Document Type: Article

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