Role of histamine release in nonspecific vasodilatation during anodal and cathodal iontophoresis

Microvascular Research

Volumn 67, Issue 2, 2004, Pages 192-196

  Horiuchi, Yoshihito ^a,b   Droog, Erik J ^a   Henricson, Joakim ^a   Wikström, Thore ^b   Lennqvist, Sten ^b   Sjöberg, Folke ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b Centre for Teaching and Research in Disaster Medicine and Traumatology (KMC)   (Sweden)

Author keywords

Cetirizine; EMLA; Histamine; Iontophoresis; Laser Doppler; Microcirculation; Nonspecific vasodilatation

Indexed keywords

CETIRIZINE; EMLA; HISTAMINE; SODIUM CHLORIDE;

ADULT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HISTAMINE RELEASE; HUMAN; HUMAN EXPERIMENT; IONTOPHORESIS; NORMAL HUMAN; PRIORITY JOURNAL; SENSORY NERVE; VASODILATATION;

ADMINISTRATION, ORAL; ADULT; ANESTHETICS, LOCAL; CETIRIZINE; CONFOUNDING FACTORS (EPIDEMIOLOGY); HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HISTAMINE RELEASE; HUMANS; IONTOPHORESIS; LIDOCAINE; NEURONS, AFFERENT; PRILOCAINE; SODIUM CHLORIDE; VASODILATION;

EID: 1542328798     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mvr.2003.12.002     Document Type: Article

References (18)

1. Barnes P.J., Brown M.J., Dollery C.T., Fuller R.W., Heavey D.J., Ind P.W. Histamine is released from skin by substance P but does not act as the final vasodilatation in the axon reflex. Br. J. Dermatol. 88:1986;741-745.
2. Berghoff M., Kathpal M., Kilo S., Hilz M.J., Freeman R. Vascular and neural mechanisms of ACh-mediated vasodilatation in the forearm cutaneous microcirculation. J. Appl. Physiol. 92:2002;780-788.
3. Berliner M.N. Skin microcirculation during tapwater iontophoresis in human: cathode stimulates more than anode. Microvasc. Res. 54:1995;74-80.
4. Bjerring P., Andersen P.H., Arendt-Nielsen L. Vascular response of human skin after analgesia with EMLA cream. Br. J. Anaesth. 63:1989;655-660.
5. Clough G.F., Bennett A.R., Church M.K. Effect of H1 antagonists on the cutaneous vascular response to histamine and bradykinin: a study using scanning laser Doppler imaging. Br. J. Dermatol. 138:1998;806-814.
6. Couture R., Cuello A.C. Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat. J. Physiol. 346:1984;273-285.
7. Durand S., Fromy B., Bouyé P., Saumet J.L., Abraham P. Current-induced vasodilatation during water iontophoresis (5 min, 0.10 mA) is delayed from current onset and involves aspirin sensitive mechanisms. J. Vasc. Res. 39:2002;59-71.
8. Ehrenström-Reiz G.M., Reiz S.L. EMLA - a eutectic mixture of local anaesthetics for topical anaesthesia. Acta Anaesthesiol. Scand. 26:1982;596-598.
9. Furue M., Terao H., Koga T. Effect of cetirizine and epinastine on the skin response to histamine iontophoresis. J. Dermatol. Sci. 25:2001;59-63.
10. Grossmann M., Jamieson M.J., Kellogg D.L. Jr., Kosiba W.A., Pergola P.E., Crandall C.G., Shepherd A.M.M. The effect of iontophoresis on the cutaneous vasculature: evidence for current-induced hyperemia. Microvasc. Res. 50:1995;444-452.
11. Johns R.A. Local anesthetics inhibit endothelium-dependent vasodilatation. Anesthesiology. 70:1989;805-811.
12. Kiernan J.A. Degranulation of mast cells following antidromic stimulation of cutaneous nerve. J. Anat. 111:1972;349-350.
13. Kirchner A., Stefan H., Schmelz M., Haslbeck K.M., Birklein F. Influence of vagus nerve stimulation on histamine-induced itching. Neurology. 59:2002;108-112.
14. Lewis T. The Blood Vessels of the Human Skin and their Responses. 1927;67 Shaw & Sons Ltd. London.
15. Morris S.J., Shore A.C. Skin blood flow responses to the iontophoresis of acetylcholine and sodium nitroprusside in man: possible mechanisms. J. Physiol. 496:1996;531-542.
16. Petersen L.J., Church M.K., Skov P.S. Histamine I released in the wheal but not the flare following challenge of human skin in vivo: a microdialysis study. Clin. Exp. Allergy. 27:1997;284-295.
17. Quignard J.F., Ryckwaert F., Albat B., Nargeot J., Richard S. A novel tetrodotoxin-sensitive Na+ current in cultured human coronary myocytes. Circ. Res. 80:1997;377-382.
18. Wårdell K., Naver H.K., Nilsson G.E., Wallin B.G. The cutaneous vascular axon reflex in humans characterized by laser Doppler perfusion imaging. J. Physiol. (London). 460:1993;185-199.