Bioequivalence of two different formulations of bicalutamide;Bioequivalencia de dos formulaciones orales de bicalutamida

Informe Medico

Volumn 5, Issue 6, 2003, Pages 225-230

  Matheus, Rodolfo ^a   Arnal, Henrique ^a   Uzcátegui, Erika ^b   Cardona, Raúl ^c  

^a HOSPITAL UNIVERSITARIO DE CARACAS   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c ICARM ^*  (Venezuela)

Author keywords

Bicalutamide; Bioequivalence; Prostate Cancer

Indexed keywords

ANTIANDROGEN; BICALUTAMIDE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CENTRIFUGATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BINDING; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG PROTEIN BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PROSTATE CANCER; REFERENCE VALUE; SIDE EFFECT; TABLET;

EID: 1542328220     PISSN: 13169688     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Furr BJ. "Casodex" (ICI 176.334). A new, pure, peripherally-selective antiandrogen: preclinal studies. Hormone Res. 1989;32(Suppl.1):69-76.
2. Newling DWW. The response of advanced prostatic cancer to a new non-steroidal antiandrogen: results of a multicenter open phase II study of "Casodex". Eur Urol 1990;18(Suppl.3):18-21.
3. Le Dictionnaire Vidal 2000. Editions du Vidal, Paris, pag. 337.
4. McKillop D, Boyle DW, Cockshott ID, Jones DC, Phillips PJ, Yates RA. Metabolism and enantioselective pharmacokinetics of Casodex in man. Xenobiotica 1993;23:1241-1253.
5. Normas de Junta Revisora de Productos Farmacéuticos. Instituto Nacional de Higiene "Rafael Rangel", Ministerio de Salud y Desarrollo Social, Caracas, 1998.
6. Le Dictionnaire Vidal 2000. Ibid
7. Normas de Junta Revisora de Productos Farmacéuticos. Reglamento de Investigación en Farmacoloía Clínica. Instituto Nacional de Higiene "Rafael Rangel", Ministerio de Salud y Desarrollo Social, Caracas, 1998.