Is recombinant Human Erythropoietin Therapy Disadvantageous in Head and Neck Cancer Patients under Radiotherapy?;Verschlechtert die Gabe von rekombinantem humanem Erythropoietin die Prognose von Patienten mit Kopf-Hals-Tumoren unter Radiotherapie?

Strahlentherapie und Onkologie

Volumn 180, Issue 3, 2004, Pages 179-180

  Jelkmann, Wolfgang ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

FERROUS GLUCONATE; IRON SACCHARATE; PLACEBO; RECOMBINANT ERYTHROPOIETIN;

CANCER CONTROL; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HEAD AND NECK CANCER; HEMOGLOBIN DETERMINATION; HUMAN; MAJOR CLINICAL STUDY; NOTE; OXYGEN CONCENTRATION; OXYGENATION; RADIOSURGERY; RANDOMIZED CONTROLLED TRIAL;

EID: 1542319902     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (8)

1. Acs G, Acs P, Beckwith SM, et al. Erythropoietin and erythropoietin receptor expression in human cancer. Cancer Res 2001;61:3561-5.
2. Glaser CM, Millesi W, Kornek GV, et al. Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx. Int J Radiat. Oncol Biol Phys 2001;50:705-15.
3. Henke M, Laszing R, Rübe C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 2003;362:1255-60.
4. Leyland-Jones B. Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol 2003;4:459-60.
5. Rizzo JD, Lichtin AE, Woolf SH, et al. Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology. Blood 2002;100:2303-20.
6. Vaupel P, Thews O, Kelleher DK, Hoecket M. Oxygenation of human tumors: the Mainz experience. Strahlenther Onkol 1998;174:SupplIV:6-12.
7. Weiss G. Eisen, Infektion und Anämie - eine klassische Triade. Wien Klin Wochenschr 2002;114:357-67.
8. Yasuda Y, Fujita Y, Matsuo T, et al. Erythropoietin regulates tumour growth of human malignancies. Carcinogenesis 20034;24:1021-9.