1H Magnetic Resonance Spectroscopy of Preinvasive and Invasive Cervical Cancer: In Vivo-Ex Vivo Profiles and Effect of Tumor Load

Journal of Magnetic Resonance Imaging

Volumn 19, Issue 3, 2004, Pages 356-364

  Mahon, Marrita M ^a   Cox, I Jane ^a   Dina, Roberto ^a   Soutter, W Patrick ^a   McIndoe, G Angus ^a   Williams, Andreanna D ^a   DeSouza, Nandita M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Choline; Lipids; Magnetic resonance spectroscopy; Triglycerides; Tumor load

Indexed keywords

CHOLINE; LIPID; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CALCULATION; CANCER INVASION; CARCINOMA IN SITU; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EX VIVO STUDY; FEMALE; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IN VIVO STUDY; INTERMETHOD COMPARISON; MAGIC ANGLE SPINNING TECHNIQUE; METABOLITE; PREDICTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PUNCH BIOPSY; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; STATISTICAL SIGNIFICANCE; TECHNIQUE; TUMOR BIOPSY; TUMOR LOAD; TUMOR VOLUME; UTERINE CERVIX BIOPSY; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA IN SITU; VAGINA;

ADENOCARCINOMA; ADULT; AGED; ANALYSIS OF VARIANCE; CARCINOMA, SQUAMOUS CELL; CERVICAL INTRAEPITHELIAL NEOPLASIA; CHOLINE; DISEASE PROGRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; NEOPLASM INVASIVENESS; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; TRIGLYCERIDES; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 1542319072     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.20012     Document Type: Article

References (38)

1. 1H nuclear MR spectroscopy for evaluation of human uterine cervical carcinoma. AJR Am J Roentgenol 1998;170:1279-1282.
2. 1H magnetic resonance spectroscopy of invasive cervical cancer: an in vivo study with ex vivo corroboration. NMR Biomed 2004;17:1-9.
3. 1H MRS. Magn Reson Med 1990;13: 324-331.
4. 1H magnetic resonance spectroscopy and biochemical study. Magn Reson Med 1993;29:149-157.
5. 1H NMR spectroscopic characterization of perchloric acid extracts from breast carcinomas and non-involved breast tissue. NMR Biomed 1994;7:181-194.
6. Millis KK, Weybright P, Campell N, et al. Classification of human liposarcoma and lipoma using ex vivo NMR spectroscopy. Magn Reson Med 1999;41:257-267.
7. 1H NMR spectroscopy at 9.4 T. FEBS Lett 2001;494:112-116.
8. Mahon MM, deSouza, NM, Dina R, McIndoe GA, Soutter WP, Cox IJ. Detecting molecular changes in malignant progression: magic angle spinning MR spectroscopy of cervical cancer. Proc Am Assoc Cancer Res 2002;43:745.
9. Delikatny EJ, Russell P, Hunter JC, et al. Proton MR and human cervical neoplasia: ex vivo spectroscopy allows distinction of invasive carcinoma of the cervix from carcinoma in situ and other preinvasive lesions. Radiology 1993;188:791-796.
10. Cheng LL, Chang IW, Louis DN, Gonzalez RG, Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens. Cancer Res 1998;58:1825-1832.
11. 1H nuclear magnetic resonance spectroscopy of intact cells. Magn Reson Med 1998;39:337-345.
12. deSouza NM, Scoones D, Krausz T, Gilderdale DJ, Soutter WP. High resolution MR imaging of stage I cervical neoplasia with a dedicated transvaginal coil: MR features and correlation of imaging and pathological findings. AJR Am J Roentgenol 1996;166:553-559.
13. 1H MRS ex vivo. Proc Int Soc Magn Reson Med 1999;7:39.
14. Dina R, Capitanio A, Damiani S. A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid. Cytopathology 2000;11:124-128.
15. Cross SS. Observer accuracy in estimating proportions in images: implications for the semiquantitative assessment of staining reactions and a proposal for a new system. J Clin Pathol 2001;54:385-390.
16. 1H NMR spectroscopy. FEBS Lett 2000;486: 225-229.
17. 31P-MR spectroscopy of primary and recurrent human brain tumours in vitro: malignancy-characteristic profiles of water soluble and lipophilic spectral components. NMR Biomed 2001;14:307-317.
18. Mountford CE, Wright LC. Organization of lipids in the plasma membranes of malignant and stimulated cells: a new model. Trends Biochem Sci 1988;13:172-177.
19. Ferretti A, Knijn A, Iorio E, et al. Biophysical and structural characterization of 1H-NMR-detectable mobile lipid domains in NIH-3T3 fibroblasts. Biochim Biophys Acta 1999;1438:329-348.
20. Callies R, Sri-Pathmanathan RM, Ferguson DYP, Brindle KM. The appearance of neutral lipid signals in the 1H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets. Magn Reson Med 1993;29:546-550.
21. Barba I, Cabanas ME, Arus C. The relationship between nuclear magnetic resonance-visible lipids, lipid droplets and cell proliferation in cultured C6 cells. Cancer Res 1999;59:1861-1868.
22. 1H MRS-visible mobile lipids in H-ras transformed tumorigenic fibroblasts with respect to their untransformed parental cells. Cell Mol Biol 1997; 43:691-701.
23. 1H MRS of high-grade astrocytomas: mobile lipid accumulation in necrotic tissue. NMR Biomed 1994;7:149-155.
24. 1H MR spectroscopy. NMR Biomed 1994;7: 172-180.
25. 1HMRS in vivo brain tumors: experience of the Siemens co-operative clinical trial. Anti-cancer Res 1996;16:1533-1538.
26. 31P MRS. Magn Reson Med 1998;40:411-420.
27. Smith TA, Eccles S, Ormerod MG, Tombs AJ, Titley JC, Leach MO. The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate. Br J Cancer 1991;64:821-826.
28. Blankenberg FG, Katsikis PD, Storrs RW, et al. Quantitative analysis of apoptotic cell death using proton nuclear magnetic resonance spectroscopy. Blood 1997;89:3778-3786.
29. Le Moyec L, Tatoud R, Degeorges A, et al. Proton nuclear magnetic resonance spectroscopy reveals cellular lipids involved in resistance to adriamycin and taxol by the K562 leukemia cell line. Cancer Res 1996;56:3461-3467.
30. Ronnov-Jessen L, Petersen OW, Bissell MJ. Cellular changes involved in conversion of normal to malignant breast; importance of the stromal reaction. Physiol Rev 1996;76:69-125.
31. Brummer O, Bohmer G, Hollwitz B, Flemming P, Petry KU, Kunhle H. MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation-an immunohistochemical study. Gynecol Oncol 2002;84:222-227.
32. Rowley DR. What might a stromal response mean to prostate cancer progression? Cancer Metastasis Review 1998;17:411-419.
33. Keevil SF, Newbold MC. The performance of volume selective sequences for in vivo NMR spectroscopy: implications for quantitative MRS. Magn Reson Imaging 2001;19:1217-1226.
34. Yongbi NM, Payne GS, Collins DJ, Leach MO. Quantification of signal selection efficiency, extra volume suppression and contamination for ISIS, STEAM and PRESS localised 1H-NMR spectroscopy using an EEC localisation test object. Phys Med Biol 1995;40: 1293-1303.
35. Shimizu H, Kumabe T, Shirane R, Yoshimoto T. Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas. AJNR Am J Neuroradiol 2000;21:659-665.
36. Ackerstaff E, Pflug BR, Nelson JB, Bhujwalla ZM. Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells. Cancer Res 2001;61:3599-3603.
37. Allen JR, Prost RW, Griffith OW, Erickson SJ, Erickson BA. In vivo proton (H1) magnetic resonance spectroscopy for cervical carcinoma. Am J Clin Oncol 2001;24:522-529.
38. 1H NMR spectroscopy in organs and tissues using slow magic angle spinning. Magn Reson Med 2001;46:213-218.