Focal network involvement in generalized seizures: New insights from electroconvulsive therapy

Epilepsy and Behavior

Volumn 5, Issue 1, 2004, Pages 3-12

  McNally, Kelly A ^a   Blumenfeld, Hal ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brainstem; Consciousness; Depression; Epilepsy; Grandmal; Memory; SPECT; Thalamus; Tonic clonic seizures

Indexed keywords

TECHNETIUM 99M; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M;

ASSOCIATION CORTEX; BIOLOGICAL MODEL; BRAIN REGION; ELECTROCONVULSIVE THERAPY; FRONTAL CORTEX; GRAND MAL SEIZURE; HUMAN; NERVE CELL NETWORK; NEUROIMAGING; PARIETAL LOBE; PREFRONTAL CORTEX; RETROSPECTIVE STUDY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL CORTEX; TONIC CLONIC SEIZURE; VERBAL MEMORY; BLOOD FLOW; BRAIN CORTEX; BRAIN MAPPING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; ELECTROENCEPHALOGRAPHY; HEMISPHERIC DOMINANCE; HISTOLOGY; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; SEIZURE; VASCULARIZATION;

BRAIN MAPPING; CEREBRAL CORTEX; ELECTROCONVULSIVE THERAPY; ELECTROENCEPHALOGRAPHY; FUNCTIONAL LATERALITY; HUMANS; NERVE NET; REGIONAL BLOOD FLOW; SEIZURES; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 1542318176     PISSN: 15255050     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yebeh.2003.10.020     Document Type: Review

References (91)

1. ILAE. P Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 1981 22 489-501
2. Avoli M. Gloor P. Kostopoulos G. et al Generalized Epilepsy 1990 Birkhauser Boston
3. Browning R.A. Nelson D.K. Modification of electroshock and pentylenetetrazol seizure patterns in rats after precollicular transections Experimental Neurology 93 1986 546-556
4. Crunelli V. Leresche N. Childhood absence epilepsy: genes, channels, neurons and networks Nature Reviews Neuroscience 3 2002 371-382
5. McCormick D.A. Contreras D. On the cellular and network bases of epileptic seizures Annual Review of Physiology 63 2001 815-846
6. Vergnes M. Marescaux C. Depaulis A. Mapping of spontaneous spike and wave discharges in Wistar rats with genetic generalized non-convulsive epilepsy Brain Research 523 1990 87-91
7. Coenen A.M. Drinkenburg W.H. Inoue M. et al Genetic models of absence epilepsy, with emphasis on the WAG/Rij strain of rats Epilepsy Research 12 1992 75-86
8. Meeren H.K. Pijn J.P. Van Luijtelaar E.L. et al Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats Journal of Neuroscience 22 2002 1480-1495
9. Blumenfeld H. From Molecules to Networks: Cortical/Subcortical Interactions in the Pathophysiology of Idiopathic Generalized Epilepsy Epilepsia 44 Suppl. 2 2003 7-15
10. Nersesyan H. Herman P. Maandag N. et al Changes in neuronal firing and cerebral blood flow during spike-wave seizures, tonic-clonic seizures, and somatosensory processing Soc. Neurosci. Abs. 2003
11. Nersesyan H. Patel S. Rivera M. et al BOLD fMRI signal changes do not involve the whole brain uniformly during spike-wave seizures and bicuculline-induced generalized tonic-clonic seizures in WAG/Rij Rats Soc. Neurosci. Abs. 2003
12. Nersesyan H. Hyder F. Rothman D. et al BOLD fMRI and Electrophysiological Recordings of Spike-Wave Seizures in WAG/Rij Rats Epilepsia (American Epilepsy Society Abstracts) 43 Suppl 7 2002-272
13. Nersesyan H, Herman P, Hyder F, et al. Seizure activity vs. normal somatosensory processing: dynamic changes in neuronal firing and cerebral blood flow in rat cortex microdomains. submitted 2003
14. Nersesyan H, Hyder F, Rothman D, et al. Dynamic fMRI and EEG recordings during spike-wave seizures and generalized tonic-clonic seizures in WAG/Rij rats, submitted 2003
15. Nersesyan H, Hyder F, Rothman D, et al. Comparison of BOLD fMRI and Electrophysiology Recordings during Spike-Wave Seizures in WAG/Rij Rats, Society for Neuroscience, Abstracts, 2002;Vol. 28
16. 14C] mapping of progressive states of status epilepticus induced by amygdala stimulation in rat Brain Res. 460 1988 96-102
17. 14C-2-deoxyglucose study in the lithium-pilocarpine model in rat Neuroscience 64 1995 1057-1073
18. Ackermann R.F. Engel J.Jr. Phelps M.E. Identification of seizure-mediating brain structures with the deoxyglucose method: studies of human epilepsy with positron emission tomography, and animal seizure models with contact autoradiography Adv. Neurol. 44 1986 921-934
19. 14C] after various forms and durations of status epilepticus induced by stimulation of a kindled amygdala focus in rats Epilepsy Res 10 1991 119-133
20. Dreifuss E.F. Henriksen O. Classification of epileptic seizures and the epilepsies Acta Neurol. Scand. Suppl. 140 1992 8-17
21. Leutmezer F. Lurger S. Baumgartner C. Focal features in patients with idiopathic generalized epilepsy Epilepsy Research 2002 296-300
22. Bell W.J. Walczak T.S. Shin C. et al Painful generalized clonic and tonic-clonic seizures with retained consciousness Journal of Neurology, Neurosurgery - Psychiatry 1997 792-795
23. Kiley M.A. Smith S.J.M. Sander J.W. Idiopathic generalized epilepsy presenting with hemiconvulsive seizures Epilepsia 41 2000 1633-1636
24. Lombroso C.T. Consistent EEG focalities detected in subjects with primary generalized epilepsies monitored for two decades Epilepsia 38 1997 797-812
25. Pavone A. Niedermeyer E. Absence seizures and the frontal lobe Clinical Electroencephalography 31 2000 153-156
26. Lagae L. Pauwels J. Monte C.P. et al Frontal absences in children European Journal of Pediatric Neurology 2001 243-251
27. Engel J.Jr. Kuhl D.E. Phelps M.E. Patterns of human local cerebral glucose metabolism during epileptic seizures Science 218 1982 64-66
28. Engel J.Jr. Ackermann R.F. Kuhl D.E. et al Brain imaging of glucose utilization in convulsive disorders Research Publications - Association for Research in Nervous - Mental Disease 63 1985 163-184
29. Theodore W.H. Brooks R. Margolin R. et al Postiron emission tomography in generalized seizures Neurology 1985 684-690
30. Salek-Haddadi A. Lemieux L. Merschhemke M. et al. Functional magnetic resonance imaging of human absence seizures Annals of Neurology 2003 663-667
31. Kotagal P. Bleasel A. Geller E. et al Lateralizing value of asymmetric tonic limb posturing observed in secondarily generalized tonic-clonic seizures Epilepsia 41 2000 457-462
32. Jobst B.C. Williamson P.D. Neuschwander T.B. et al Secondarily generalized seizures in mesial temporal epilepsy: clinical characteristics, lateralizing signs, and association with sleep-wake cycle Epilepsia 42 2001 1279-1287
33. Leutmezer F. Woginger S. Antoni E. et al Asymmetric ending of secondarily generalized seizures Neurology 2002 1252-1254
34. Lee B.I. Markand O.N. Wellman H.N. et al HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures Epilepsia 28 1987 305-311
35. Koc E. Serdaroglu A. Kapucu O. et al Ictal and interictal SPECT in a newborn infant with intractable seizure Acta Paediatrica 86 1997 1379-1381
36. Green C. Buchhalter J.R. Ictal SPECT in a 16-day-old infant Clin. Nucl. Med. 18 1993 768-770
37. Blumenfeld H. Westerveld M. Ostroff R.B. et al. Selective frontal, parietal and temporal networks in generalized seizures Neuroimage 19 2003 1556-1566
38. American Psychiatric Association, C.o.E.T. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging. 2nd ed. Washington, DC: American Psychiatric Association; 2001
39. Kellner C.H. Pritchett J.T. Beale M.D et al Handbook of ECT 1997 American Psychiatric Press, Inc Washington, DC
40. Browning R.A. Turner F.J. Simonton R.L. et al Effect of midbrain and pontine tegmental lesions on the maximal electroshock seizure pattern in rats Epilepsia 22 1981 583-594
41. Fisher R.S. Animal models of the epilepsies Brain Research - Brain Research Reviews 14 1989 245-278
42. Kriss A. Blumhardt L.D. Halliday A.M. et al. Neurological asymmetries immediately after unilateral ECT Journal of Neurology, Neurosurgery - Psychiatry 41 1978 1135-1144
43. Kriss A. Halliday A.M. Halliday E. et al. EEG immediately after unilateral ECT Acta Psychiatrica Scandinavica 58 1978 231-244
44. Sackeim H.A. Prudic J. Devanand D.P. et al. Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy N Engl. J. Med. 328 1993 839-846
45. Lisanby S.H. Maddox J.H. Prudic J. et al. The effects of electroconvulsive therapy on memory of autobiographical and public events Archives of General Psychiatry 57 2000 581-590
46. Sackeim H.A. Prudic J. Devanand D.P et al. A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities Archives of General Psychiatry 57 2000 425-434
47. Weiner R.D. Rogers H.J. Davidson J.R.T. et al. Effects of stimulus parameters on cognitive side effects Ann. NY Acad. Sci. 462 1986 315-325
48. Letemendia F. Delva N. Rideburgm M. et al. Therapeutic advantage of bifrontal electrode placement in ECT Psychol. Med. 23 1993 349-360
49. Bailine S. Rifkin A. Kayne E. et al. Comparison of bifrontal and bitemporal ECT for major depression American Journal of Psychiatry 157 2000 121-123
50. Lawson J. Inglis J. Delva N. et al. Electrode placement in ECT: cognitive effects Psychol Med 20 1990 335-344
51. Sackeim H.A. Nobler M.S. Prudic J. et al. Acute effects of electroconvulsive therapy on hemispatial neglect Neuropsychiatry, Neuropsychology, - Behavioral Neurology 5 1992 151-160
52. Luber B. Nobler M.S. Moeller J.R. et al. Quantitative EEG during seizures induced by electroconvulsive therapy: relations to treatment modality and clinical features II. Topographic analyses Journal of Ect. 16 2000 229-243
53. Boylan L.S. Devanand D.P. Lisanby S.H. et al. Focal prefrontal seizures induced by bilateral ECT Journal of ECT 17 2001 175-179
54. Sackeim H.A. Luber B. Moeller J.R. et al. Electrophysiological correlates of the adverse cognitive effects of electroconvulsive therapy Journal of Ect 16 2000 110-120
55. Heikman P. Salmelin R. Makela J.P. et al. Relation between frontal 3-7 Hz MEG activity and the efficacy of ECT in major depression Journal of ECT 17 2001 136-140
56. Sperling W. Martus P. Alschbach M. Evaluation of neuronal effects of electroconvulsive therapy by magnetoencephalography (MEG) Prog. Neuro-Psychopharmacol Biol. Psychiatr. 24 2000 1339-1354
57. Nobler M.S. Sackeim H.A. Prohovnik I. et al. Regional cerebral blood flow in mood disorders, III. Treatment and clinical response Arch Gen Psychiatry 51 1994 884-897
58. Nobler M.S. Oquendo M.A. Kegeles L.S. et al. Decreased regional brain metabolism after ECT Am. J. Psychiatry 158 2001 305-308
59. Prohovnik I. Sackeim H.A. Decina P. Malitz S. Acute reductions of regional cerebral blood flow following electroconvulsive therapy. Interactions with modality and time Annals of the New York Academy of Sciences 462 1986 249-262
60. Rosenberg R. Vorstrup S. Andersen A. et al. Effect of ECT on cerebral blood flow in melancholia assesed with SPECT Convuls. Ther. 4 1988 62-73
61. 99mTc-Exametazime into brain in major depression shown with single photon emission tomography J. Affect. Disord. 30 1994 27-34
62. Henry M.E. Schmidt M.E. Matochick J.A. et al. The effects of ECT on brain glucose: A pilot FDG PET study Journal of ECT 17 2001 33-40
63. Volkow N.D. Bellar S. Mullani N. et al. Effects of electroconvulsive therapy on brain glucose metabolism: A preliminary study Convuls Ther 4 1988 199-205
64. Bonne O. Krausz Y. Shapira B. et al. Increased Cerebral blood flow in depressed patients responding to electroconvulsive therapy Journal of Nuclear Medicine 1996 1075-1080
65. Milo T.J. Kaufman G.E. Barnes W.E. et al. Changes in regional cerebral blood flow after electroconvulsive therapy for depression Journal of ECT 17 2001 15-21
66. 99mtechnetium HMPAO SPECT Prog. Neuro-Psychopharmacol Biol. Psychiatry 27 2003 15-19
67. Drevets W.C. Price J.L. Simpson J.R. et al. Subgenual prefrontal cortex abnormalities in mood disorder Nature 386 1997 824-827
68. Bonne O. Krausz Y. Gorfine M. et al. Cerebral hypoperfusion in medication resistant, depressed patients assessed by Tc99m HMPAO SPECT J. Affect Disord 41 1996 163-171
69. Bajc M. Medved V. Basic M. et al. Acute effect of electroconvulsive therapy on brain perfusion assessed by Tc99m-hexamethylpropyleneamineoxim and single photon emission computed tomography Acta Psychiatrica Scandinavica 80 1989 421-426
70. Elizagarate E. Cortes J. Pinto A.G. et al Study of the influence of electroconvulsive therapy on the regional cerebral blood flow by HMPAO-SPECT Journal of Affective Disorders 2001 55-59
71. Sestoft D. Meden P. Hemmingsen R. et al. Disparity in regional cerebral blood flow during electrically induced seizure Acta Psychiatrica Scandinavica 88 1993 140-143
72. Devous M.D.Sr. Leroy R.F. Homan R.W. Single photon emission computed tomography in epilepsy Seminars in Nuclear Medicine 20 1990 325-341
73. O'Brien T.J. So E.L. Mullan B.P. et al. Subtraction ictal SPECT co-registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus Neurology 50 1998 445-454
74. Zubal I.G. Spencer S.S. Imam K. et al. Difference images calculated from ictal and interictal technetium-99m-HMPAO SPECT scans of epilepsy Journal of Nuclear Medicine 36 1995 684-689
75. Chang D.J. Zubal I.G. Gottschalk C. et al. Comparison of Statistical Parametric Mapping and SPECT Difference Imaging in Patients with Temporal Lobe Epilepsy Epilepsia 43 2002 68-74
76. Spanaki M.V. Spencer S.S. Corsi M. et al. Sensitivity and specificity of quantitative difference SPECT analysis in seizure localization Journal of Nuclear Medicine 40 1999 730-739
77. Blumenfeld H. McNally K.A. Ostroff R. et al. Targeted prefrontal cortical activation with bifrontal ECT Psychiat. Res. Neuroimag 125 2003 165-170
78. Friston K.J. Holmes A. Poline J.B. et al. Detecting activations in PET and fMRI: levels of inference and power Neuroimage 4 1996 223-235
79. Acton P.D. Friston K.J. Statistical parametric mapping in functional neuroimaging: beyond PET and fMRI activation studies European Journal of Nuclear Medicine 25 1998 663-667
80. Guillery R.W. Sherman S.M. Thalamic relay functions and their role in corticocortical communication: generalizations from the visual system Neuron 33 2002 163-175
81. Lumer E.D. Friston K.J. Rees G. Neural correlates of perceptual rivalry in the human brain Science 280 1998 1930-1934
82. Blumenfeld H. Taylor J. Why do seizures cause loss of consciousness? The Neuroscientist 9 5 2003 301-310
83. Leonards U. Sunaert S. Van Hecke P. et al. Attention mechanisms in visual search - an fMRI study Journal of Cognitive Neuroscience 12 Suppl 2 2000 61-75
84. Velasco F. Velasco M. Pacheco T. et al. Comparative effects of topical perfusions of pentylenetetrazol in the mesencephalon and cerebral cortex of cats Experimental Neurology 87 1985 533-543
85. Browning R.A. Role of the brain-stem reticular formation in tonic-clonic seizures: lesion and pharmacological studies FASEB 44 1985 2425-2431
86. Faingold C.L. Neuronal networks in the genetically epilepsy-prone rat Advances in Neurology 79 1999 311-321
87. Gale K. Subcortical structures and pathways involved in convulsive seizure generation Journal of Clinical Neurophysiology 9 1992 264-277
88. Squire S.R. Slater P.C. Bilateral and unilateral ECT: effects on verbal and nonverbal memory American Journal of Psychiatry 135 1978 1316-1320
89. Sackeim H. Portnoy S. Neeley P. Cognitive consequences of low-dose electroconvulsive therapy Ann. NY Acad. Sci. 462 1986 326-340
90. Milner B. Psychological aspects of focal epilepsy and its neurosurgical management Advances in Neurology 8 1975 299-321
91. Sass K.J. Buchanan C.P. Kraemer S. et al. Verbal memory impairment resulting from hippocampal neuron loss among epileptic patients with structural lesions Neurology 45 1995 2154-2158