Skeletal Scintigraphy in the Multimodality Assessment of Young Children with Acute Skeletal Symptoms

Clinical Nuclear Medicine

Volumn 28, Issue 9, 2003, Pages 746-754

  Connolly, Leonard P ^a   Connolly, Susan A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Avascular necrosis; Fracture; Osteomyelitis; Septic arthritis; Skeletal scintigraphy; Transient synovitis

Indexed keywords

AVASCULAR NECROSIS; BACTERIAL ARTHRITIS; BONE SCINTISCANNING; CHILD; DIAGNOSTIC IMAGING; FRACTURE; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOMYELITIS; PERTHES DISEASE; REVIEW; SYNOVITIS;

ARTHRITIS, INFECTIOUS; BONE AND BONES; BONE DISEASES; CHILD; CHILD, PRESCHOOL; FEMALE; FRACTURES, BONE; HUMANS; INFANT; LEGG-PERTHES DISEASE; MALE; OSTEOMYELITIS; SYNOVITIS;

EID: 1542317387     PISSN: 03639762     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.rlu.0000082663.54359.d9     Document Type: Review

References (55)

1. Scott RJ, Christofersen MR, Robertson WW Jr, et al. Acute osteomyelitis in children: a review of 116 cases. J Pediatr Orthop. 1990;10:649.
2. Nixon GW. Hematogenous osteomyelitis of metaphyseal-equivalent locations. AJR Am J Roentgenol. 1978;130:123.
3. Nixon G. Acute hematogenous osteomyelitis. Pediatr Ann. 1976;5:64.
4. Faden H, Grossi M. Acute osteomyelitis in children. Am J Dis Child. 1991;145:65.
5. Syrogiannopoulos GA, Nelson JD. Duration of antimicrobial therapy for acute suppurative osteoarticular infections. Lancet. 1988;i:37.
6. Nelson JD. Acute osteomyelitis in children. Infect Dis Clin North Am. 1990;4:513.
7. Gilday DL, Paul DJ, Paterson J. Diagnosis of osteomyelitis in children by combined blood pool and bone imaging. Radiology. 1975;117:331.
8. Majd M, Frankel RS. Radionuclide imaging in skeletal inflammatory and ischemic disease in children. AJR Am J Roentgenol. 1976;126:832.
9. Treves S, Khettry J, Broker FH, et al. Osteomyelitis: early scintigraphic detection in children. Pediatrics. 1976;57:173.
10. Connolly LP, Connolly SA, Drubach LA, et al. Acute hematogenous osteomyelitis of children: assessment of skeletal scintigraphy-based diagnosis in the era of MRI. J Nucl Med. 2002;43:1310.
11. Mazur JM, Ross G, Cummings RJ, et al. Usefulness of magnetic resonance imaging for the diagnosis of acute musculoskeletal infections in children. J Pediatr Orthop. 1995;15:144.
12. Schauwecker DS. The scintigraphic diagnosis of osteomyelitis. AJR Am J Roentgenol. 1992;158:9.
13. Jones DC, Cady RB. "Cold" bone scans in acute osteomyelitis. J Bone Joint Surg Br. 1981;63:376.
14. Teates CD, Williamson BRJ. "Hot and cold" bone lesion in acute osteomyelitis. AJR Am J Roentgenol. 1977;129:517.
15. Jaramillo D, Treves ST, Kasser JR, et al. Osteomyelitis and septic arthritis in childhood: appropriate use of imaging to guide treatment. AJR Am J Roentgenol. 1995;165:399.
16. Harcke HT. Role of imaging in musculoskeletal infections in children [editorial]. J Pediatr Orthop. 1995;15:141.
17. Dangman BC, Hoffer FA, Rand FF, et al. Osteomyelitis in children: gadolinium enhanced MR imaging. Radiology. 1992;182:743.
18. Fletcher BD, Scoles PV, Nelson AD. Osteomyelitis in children: detection by magnetic resonance. Work in progress. Radiology. 1984;150:57.
19. Kaiser S, Jorulf H, Hirsch G. Clinical value of imaging techniques in childhood osteomyelitis. Acta Radiol. 1998;39:523.
20. Ozonoff MB. Generalized orthopedic diseases of childhood. In: Pediatric Orthopedic Radiology. 2nd ed. Philadelphia: WB Saunders; 1992: 461-568.
21. Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: an evidence-based clinical prediction algorithm. J Bone Joint Surg Am. 1999;81:1662.
22. Volberg FM, Sumner TE, Abramson JS, et al. Unreliability of radiographic diagnosis of septic hip in children. Pediatrics. 1984;73:118.
23. Zawin JA, Hoffer FA, Rand FF, et al. Joint effusion in children with an irritable hip: US diagnosis and aspiration. Radiology. 1993;187:459.
24. Zieger MM, Dorr U, Schulz RD. Ultrasonography of hip joint effusions. Skeletal Radiol. 1987;16:607.
25. Kloiber R, Pavlosky W, Portner O, et al. Bone scintigraphy of hip joint effusions in children. AJR Am J Roentgenol. 1983;140:995.
26. Minikel J, Sty J, Simons G. Sequential radionuclide imaging in avascular pediatric hip conditions. Clin Orthop. 1983;175:202.
27. Sty JR, Wells RG, Smith WB. The child with acute leg pain. Semin Nucl Med. 1988;18:137.
28. Sty JR, Wells RG, Starshak RJ, et al. The musculoskeletal system. In: Diagnostic Imaging of Infants and Children. Vol. 3. Gaithersburg: Aspen Publishers; 1992:233-405.
29. Bensahel H, Bok B, Cavailloles F, et al. Bone scintigraphy in Perthes disease. J Pediatr Orthop. 1983;3:302.
30. Calver R, Venugopal V, Dorgan J, et al. Radionuclide scanning in the early diagnosis of Perthes' disease. J Bone Joint Surg Br. 1981;63:379.
31. Cavaillos F, Bok B, Bensahel H. Bone scintigraphy in the diagnosis and followup of Perthes disease. Eur J Nucl Med. 1982;7:327.
32. Sutherland AD, Savage JP, Paterson DC, et al. The nuclide bone-scan in the diagnosis and management of Perthes' disease. J Bone Joint Surg Br. 1980;62:300.
33. Tsao AK, Dias LS, Conway JJ, et al. The prognostic value and significance of serial bone scintigraphy in Legg-Calvé-Perthes disease. J Pediatr Orthop. 1997;17:230.
34. Sebag GH. Disorders of the hip. Magn Reson Imaging Clin North Am. 1998;6:627.
35. Bos CF, Bloem JL, Bloem RM. Sequential magnetic resonance imaging in Perthes disease. J Bone Joint Surg Br. 1991;73:219-224.
36. Pinto MR, Peterson HA, Berquist TH. Magnetic resonance imaging in early diagnosis of Legg-Calvé-Perthes disease. J Pediatr Orthop. 1989; 9:19.
37. VandeBerg B, Malghem J, Labaisse MA, et al. Avascular necrosis of the hip: comparison of contrast-enhanced and nonenhanced MR imaging with histologic correlation. Work in Progress. Radiology. 1992;182: 445.
38. Ducou le Pointe H, Haddad S, Silberman B, et al. Legg-Perthes-Calvé disease: staging by MRI using gadolinium. Pediatr Radiol. 1994;24:88.
39. Kumasaka Y, Harada K, Watanabe H, et al. Modified epiphyseal index for MRI in Legg-Calvé-Perthes disease (LCPD). Pediatr. Radiol. 1991; 21:208.
40. Egund N, Wingstrand H. Legg-Calvé-Perthes disease: imaging with M R. Radiology. 1991;179:89.
41. Jaramillo D, Kasser JR, Villegas-Medina OL, et al. Cartilaginous abnormalities and growth disturbances in Legg-Calvé-Perthes disease: evaluation with MR imaging. Radiology. 1995;197:767.
42. Weinstein SL. Legg-Calvé-Perthes disease. In: Morrisy RT, Weinstein SL, eds. Lovell and Winter's Pediatric Orthopedics. 5th ed. Philadelphia: Lippincott-Raven; 2001:957-998.
43. Lamer S, Dorgeret S, Khairouni A, et al. Femoral head vascularisation in Legg-Calvé-Perthes disease: comparison of dynamic gadolinium-enhanced subtraction MRI with bone scintigraphy. Pediatr Radiol. 2002;32:580.
44. Dunbar JS. Obscure tibial fracture of infants-the toddler's fracture. J Can Assoc Radiol. 1964;15:136.
45. Swischuk LE, John EJ, Tschoepe SD. Upper tibial hyperextension fractures in infants: another occult toddler's fracture. Pediatr Radiol. 1999;29:6.
46. Starshak RJ, Simons GW, Sty JR. Occult fracture of the calcaneusanother toddler's fracture. Pediatr Radiol. 1984;14:37.
47. Blumberg K, Patterson RJ. The toddler's cuboid fracture. Radiology. 1991;179:93.
48. Englaro EE, Gelfand MJ, Paltiel HJ. Bone scintigraphy in preschool children with lower extremity pain of unknown origin. J Nucl Med. 1992;33:351.
49. John SD, Moorthy CS, Swischuk LE. Expanding the concept of the toddler's fracture. Radiographics. 1997;17:367.
50. Miller JH, Sanderson RA. Scintigraphy of toddler's fracture. J Nucl Med. 1988;29:2001.
51. Schaller J. Arthritis as a presenting manifestation of malignancy in children. J Pediatr. 1972;81:793.
52. Cabral DA, Tucker LB. Malignancies in children who initially present with rheumatic complaints. J Pediatr. 1999;134:53.
53. Applegate KA, Connolly LP, Treves ST. Neuroblastoma presenting clinically as hip osteomyelitis: a signature diagnosis on skeletal scintigraphy. Pediatr Radiol. 1995;25:S93.
54. Clausen N, Gotze H, Pedersen A, et al. Skeletal scintigraphy and radiography at onset of acute lymphocytic leukemia in children. Med Pediatr Oncol. 1983;11:291.
55. Shalaby-Rana E, Majd M. 99mTc-MDP scintigraphic findings in children with leukemia: value of early and delayed whole-body imaging. J Nucl Med. 2001;6:878.