Synthesis and structure/NMDA receptor affinity relationships of 1-substituted tetrahydro-3-benzazepines

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 6, 2004, Pages 1439-1451

  Krull, Olaf ^a   Wünsch, Bernhard ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

(2 Bromophenyl)acetaldehyde acetal; 3 Benzazepines; Michael addition; NMDA receptor antagonists; Structure Affinity Relationship

Indexed keywords

(2 BROMOPHENYL)ACETALDEHYDE ACETAL; ACETAL DERIVATIVE; ALDEHYDE DERIVATIVE; BENZAZEPINE DERIVATIVE; HYDROXYL GROUP; METHYL GROUP; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITROSTYRENE; PHENYL GROUP; STYRENE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CORRELATION ANALYSIS; DRUG SCREENING; DRUG SYNTHESIS; HYDROGEN BOND; MOLECULAR MECHANICS; RECEPTOR BINDING; STRUCTURE ANALYSIS;

ANIMALS; BENZAZEPINES; BINDING SITES; CELL MEMBRANE; CEREBRAL CORTEX; DIZOCILPINE MALEATE; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; HYDROGEN BONDING; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PHENCYCLIDINE; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 1542301638     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.12.036     Document Type: Article

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