Study on the Structure Activity Relationships of NPTX-594, a Spider Toxin Belonging to the Type-B Acylpolyamine Structure

Bulletin of the Chemical Society of Japan

Volumn 77, Issue 2, 2004, Pages 331-340

  Wakamiya, Tateaki ^a   Kinoshita, Tomohiko ^a   Hattori, Yoshihide ^a   Yamaguchi, Yoshihiro ^a   Naoki, Hideo ^b   Corzo, Gerardo ^b   Nakajimal, Terumi ^b  

^a KINKI UNIVERSITY   (Japan)

^b SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; MOLECULES; ORGANIC POLYMERS; SYNTHESIS (CHEMICAL); TOXICITY;

BIOLOGICAL ACTIVITIES; PARALYTIC ACTIVITIES;

TOXIC MATERIALS;

4,8 DIAZA 1,12 DODECANEDIAMINE; DIAMINE DERIVATIVE; NPTX 594; POLYAMINE DERIVATIVE; SPIDER VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CONFERENCE PAPER; NEUROTOXICITY; NONHUMAN; PARALYSIS; SPIDER; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TOXIN ANALYSIS; TOXIN STRUCTURE;

EID: 1542290073     PISSN: 00092673     EISSN: None     Source Type: Journal    
DOI: 10.1246/bcsj.77.331     Document Type: Conference Paper

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28. The analog is abbreviated as Xaa-[des-Lys-(NPTX-594)] in which Xaa is the amino acid residue introduced at the place of the Lys residue in NPTX-594.