Modeling of impedance of cell-covered electrodes

Proceedings of IEEE Sensors

Volumn 2, Issue 2, 2003, Pages 1358-1363

  Greve, D W ^a   Huang, X ^a   Nguyen, D ^b   Domach, M M ^b  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Biosensor; Electrodes; Gold; Impedance

Indexed keywords

BIOSENSORS; CAPACITANCE; ELECTRIC CONDUCTIVITY; ELECTRIC VARIABLES MEASUREMENT; ELECTRODES; GOLD; INTERFACES (MATERIALS);

BIOAGENTS; CELL-COVERED ELECTRODES;

CELLS;

EID: 1542273257     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (10)

1. Giaever, I. and Keese, C.R., "Use of electric fields to monitor the dynamical aspect of cell behavior in tissue culture," IEEE Transactions on Biomedical Engineering, BME-33(2):242-247 (1986).
2. Keese, C.R. and Giaever, I., "A biosensor that monitors cell morphology with electric fields," IEEE Engineering in Medicine and Biology Magazine, June/July:402-408 (1994).
3. Tiruppathi, C., Malik, A.B., Del Vecchio, P.J., Keese, C.R., and Giaever, I., "Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function," Proc. Natl. Acad. Sci., 89:7919-7923 (1992).
4. Giaever, I. and Keese, C.R., "Micromotion of mammalian cells measured electrically," Proc. Natl. Acad. Sci., 88:7896-7900 (1991).
5. Wegener, J., Sieber, M. and Galla, H.J., "Impedance analysis of epithelial and endothelial cell monolayers cultured on gold surfaces," J. Biochem. Biophys. Methods, 32(3):151-170 (1996).
6. Ehret, R., Baumann, W., Brischwein, M., Schwinde, A., Stegbauer, K. and Wolf, B., "Monitoring of cellular behaviour by impedance measurements on inter-digitated electrode structures," Biosensors and Bioelectronics, 12(1):29-41 (1997).
7. D. Nguyen, H. Xiaoqiu, T. Afentakis, M. Hatalis, M.Domach, and D. Greve, "Screening of isolated cells via arrays of impedance sensors," (paper presented at the 225th ACS National Meeting (New Orleans)/BIOT / Sci-Mix Poster, March, 2003).
8. "The use of the Conductive Media DC Application Mode for time-harmonic problems," solution 904, support knowledge base, from htttp://www.comsol.com.
9. M. Miskian, J.J. Kasianowicz, B. Robertson, and O. Petersons, "Frequency response of alternating currents through the Staphylococcus aureus α-hemolysin ion channel," Bioelectromagnetics 22, 487 (2001).
10. Fibroblast Proliferation & Effect of Protein Kinase Inhibitor (H-7) Monitored in Microimpedance Sensor Arrays," Duc D. Nguyen, Xiaoqiu Huang, David W. Greve and Michael M. Domach, (submitted to Nature Biotechnology).