Real-time fMRI of cortico-limbic brain activity during emotional processing

NeuroReport

Volumn 15, Issue 3, 2004, Pages 527-532

  Phan, K Luan ^a   Fitzgerald, Daniel A ^a   Gao, Kunxiu ^a   Moore, Gregory J ^a   Tancer, Manuel E ^a   Posse, Stefan ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Affect; Amygdala; Anterior cingulate cortex; Brain imaging; Cortico limbic; Emotion; fMRI; Insula; Medial prefrontal cortex; Real time

Indexed keywords

ADULT; ARTICLE; AVERSION; BRAIN CORTEX; BRAIN FUNCTION; BRAIN REGION; CONTROLLED STUDY; EMOTION; EXPERIENCE; FEASIBILITY STUDY; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN EXPERIMENT; INSULA; LIMBIC CORTEX; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCEPTION; PRIORITY JOURNAL; STATISTICAL PARAMETERS; TIME; VISUAL STIMULATION;

ADULT; AMYGDALA; CEREBRAL CORTEX; COMPUTER SYSTEMS; DATA INTERPRETATION, STATISTICAL; EMOTIONS; FEMALE; HUMANS; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PHOTIC STIMULATION;

EID: 1542267702     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200403010-00029     Document Type: Article

References (26)

1. Phan KL, Wager T, Taylor SF and Liberzon I. Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage 16, 331-348 (2002).
2. Panksepp J. Affective Neuroscience: The Foundations of Human and Animal Emotions. Oxford: Oxford University Press; 1998.
3. Schienle A, Stark R, Walter B, Blecker C, Ott U, Kirsch P et al. The insula is not specifically involved in disgust processing: an fMRI study. Neuroreport 13, 2023-2026 (2002).
4. Phillips ML, Young AW, Senior C, Brammer M, Andrew C, Calder AJ et al. A specific neural substrate for perceiving facial expressions of disgust. Nature 389, 495-498 (1997).
5. Taylor SF, Liberzon I and Koeppe RA. The effect of graded aversive stimuli on limbic and visual activation. Neuropsychologia 38, 1415-1425 (2000).
6. Phan KL, Taylor SF, Welsh RC, Decker LR, Noll DC, Nichols TE et al. Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a functional magnetic resonance imaging study. Biol Psychiatry 53, 211-215 (2003).
7. Damasio AR, Grabowski TJ, Bechara A, Damasio H, Ponto LL, Parvizi J et al. Subcortical and cortical brain activity during the feeling of self-generated emotions. Nature Neurosci 3, 1049-1056 (2000).
8. Posse S, Fitzgerald D, Gao K, Habel U, Rosenberg D, Moore GJ et al. Real-time fMRI of temporolimbic regions detects amygdala activation during single-trial self-induced sadness. Neuroimage 18, 760-768 (2003).
9. Critchley H. Emotion and its disorders. Br Med Bull 65, 35-47 (2003).
10. Posse S, Binkofski F, Schneider F, Gembris D, Frings W, Habel U et al. A new approach to measure single-event related brain activity using real-time fMRI: feasibility of sensory, motor, and higher cognitive tasks. Hum Brain Mapp 12, 25-41 (2001).
11. Weiskopf N, Veit R, Erb M, Mathiak K, Grodd W, Goebel R et al. Physiological self-regulation of regional brain activity using real-time functional magnetic resonance imaging (fMRI): methodology and exemplary data. Neuroimage 19, 577-586 (2003).
12. Lang PJ, Bradley MM and Cuthbert BN. International Affective Picture System (IAPS): Technical Manual and Affective Ratings. Gainesville, FL: NIMH Center for the Study of Emotion and Attention, University of Florida; 1997.
13. Posse S, Wiese S, Gembris D, Mathiak K, Kessler C, Grosse-Ruyken ML et al. Enhancement of BOLD-contrast sensitivity by single-shot multi-echo functional MR imaging. Magn Reson Med 42, 87-97 (1999).
14. Speck O and Hennig J. Functional imaging by 10- and T2*-parameter mapping using multi-image EPI. Magn Reson Med 40, 243-248 (1998).
15. Mathiak K and Posse S. Evaluation of motion and realignment for functional magnetic resonance imaging in real time. Magn Reson Med 45, 167-171 (2001).
16. Gembris D, Taylor JG, Schor S, Frings W, Suter D and Posse S. Functional magnetic resonance imaging in real time (FIRE): sliding-window correlation analysis and reference-vector optimization. Magn Reson Med 43, 259-268 (2000).
17. Posse S, Shen Z, Kiselev V and Kemna LJ. Single-shot T(2)* mapping with 3D compensation of local susceptibility gradients in multiple regions. Neuroimage 18, 390-400 (2003).
18. Cox RW, Jesmanowicz A and Hyde JS. Real-time functional magnetic resonance imaging. Magn Reson Med 33, 230-236 (1995).
19. Talairach J and Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. Stuggart: Theime; 1988.
20. Friston KJ, Holmes AP, Worsley KJ, Poline JB, Frith CD, Frackowiak RS. Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 2, 189-210 (1995).
21. Shapira NA, Liu Y, He AG, Bradley MM, Lessig MC, James GA et al. Brain activation by disgust-inducing pictures in obsessive-compulsive disorder. Biol Psychiatry 54, 751-756 (2003).
22. Buchel C and Dolan RJ. Classical fear conditioning in functional neuroimaging. Curr Opin Neurobiol 10, 219-223 (2000).
23. Gusnard DA, Akbudak E, Shulman GL and Raichle ME. Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci USA 98, 4259-4264 (2001).
24. Hariri AR, Tessitore A, Mattay VS, Fera F and Weinberger DR. The amygdala response to emotional stimuli: a comparison of faces and scenes. Neuroimage 17, 317-323 (2002).
25. Davis M and Whalen PJ. The amygdala: vigilance and emotion. Mol Psychiatry 6, 13-34 (2001).
26. LaBar KS, Gitelman DR, Mesulam MM and Parrish TB. Impact of signal-to-noise on functional MRI of the human amygdala. Neuroreport 12, 3461-3464 (2001).