Glycosaminoglycan excretion in children with nephrotic syndrome

Pediatric Nephrology

Volumn 20, Issue 4, 2005, Pages 486-490

  Cengiz, Nurcan ^a   Bayazit, Aysun K ^b   Noyan, Aytul ^b   Anarat, Ruksan ^a   Anarat, Ali ^a  

^a BASKENT UNIVERSITY   (Turkey)

^b CUKUROVA UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

Childhood; Glycosaminoglycans; Nephrotic syndrome; Steroid resistance; Steroid sensitivity

Indexed keywords

CREATININE; GLYCOSAMINOGLYCAN; STEROID;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; CORRELATION FUNCTION; DISEASE COURSE; DISEASE SEVERITY; DRUG SENSITIVITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; PROTEINURIA; REMISSION; URINARY EXCRETION;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CREATININE; DRUG RESISTANCE; FEMALE; GLYCOSAMINOGLYCANS; HUMANS; MALE; NEPHROTIC SYNDROME; PROTEINURIA; SEVERITY OF ILLNESS INDEX; STEROIDS;

EID: 15344338656     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-004-1739-y     Document Type: Article

References (29)

1. Chang RLS (1975) Permselectivity of the glomerular capillary wall to macromolecules. Experimental studies in rats using neutral dextran. Biophys J 15:887-906
2. Bridges CR (1982) Glomerular charge alterations in humans minimal change nephropathy. Kidney Int 22:677-684
3. Carrie BJ, Salyer WR, Myers BD (1981) Minimal change nephropathy, an electrochemical disorder of the glomerular membrane. Am J Med 70:262-268
4. Salant DJ (1994) The structural biology of glomerular epithelial cells in proteinuric diseases. Curr Opin Nephrol Hypertens 3:569-574
5. Bagio B, Briani G (1984) Urinary excretion of glycosaminoglycans and brush border and lysosomal enzymes as a marker of glomerular and tubular involvement in kidney disease. Contrib Nephrol 42:107
6. Vernier RL, Klein DJ, Sisson SP, Mahan JD, Oegema TR, Brown DM (1983) Heparan-sulphate-rich anionic sites in the human glomerular basement membrane: Decreased concentration in congenital nephrotic syndrome. New Engl J Med 309:1001-1008
7. Caulfield JP, Farquhar MG (1978) Loss of anionic sites from the glomerular basement membrane in aminonucleoside nephrosis. Lab Invest 39:505-512
8. Kanwar YS (1984) Biophysiology of glomerular filtration and proteinuria. Lab Invest 51:7-21
9. Levin M, Smith C, Walters MDS, Gascoin P, Barratt TM (1985) Steroid-responsive nephrotic syndrome; a generalized disorder of membrane negative charge. Lancet 1:239-242
10. Levin M, Gascoin P, Turner MW, Barratt M (1989) A highly cationic protein in plasma and urine of children with steroid-responsive nephrotic syndrome. Kidney Int 36:867-877
11. Mynderse LA (1983) Loss of heparan sulfate proteoglycan from glomerular basement membrane of nephrotic rats. Lab Invest 48:292-302
12. Kitano Y, Yoshikawa N, Nakamura H (1993) Glomerular anionic sites in minimal change nephrotic syndrome and focal segmental glomerulosclerosis. Clin Nephrol 40:199-204
13. Mitsuhashi H, Tsukada Y, Ono K, Yano S, Naruse T (1993) Urine glycosaminoglycans and heparan sulfate excretions in adult patients with glomerular diseases. Clin Nephrol 39:231-237
14. Churge J, Habib R, White RHR (1970) Pathology of the nephrotic syndrome in children. Lancet I:1299-1302
15. De Jong JGN, Wevers RA, Liebrant-van Sambeek R (1992) Measuring urinary glycosaminoglycans in the presence of protein. Clin Chem 38:803-807
16. Paulsson M (1992) Basement membrane proteins: Structure, assembly, and cellular interactions. Crit Rev Biochem Mol Biol 27:93-127
17. Kerjaschki D, Sharky DJ, Farquar MG (1984) Identification and characterization of podocalyxin- the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol 98:1591-1596
18. Matsumura K, Yamada Saito F, Sunada Y, Shimuzu T (1997) The role of dystroglycan, a novel receptor of laminin and agrin, in cell differentiation. Histol Histopathol 12:195-203
19. Champe PC, Harvey RA (1994) Lippincott's Illustrated Reviews: Biochemistry, Glycosaminoglycans, 2nd edn. J.B. Lippincott, Philadelphia, pp 147-156
20. Soldani G, Romagloni J (1991) Experimental and clinical pharmacology of glycosaminoglycans. Drugs Exp Clin Res 17:81-85
21. Sciler MW, Venkatachalam MA, Cotran RS (1975) Glomerular epithelium: structural alterations induced by polycations. Science 189:390-393
22. Spiro RG, Mohan PS (1987) Renal basement membranes in health and disease. Biochemical exploration of the macromolecular organization of the glomerular basement membrane: Interrelationship of collagen, proteoglycan and glycoprotein components. Academic Press, London, pp 11-23
23. Groffen AJ, Ruegg MA, Dijkman H, Van den Velden TJ, Buskens CA, Van den Born J, Assmann KJ, Monnens LA, Veerkamp JH, Van den Heuvel LP (1998) Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane. J Histochem Cytochem 46:19-27
24. Groffen AJ, Veerkamp JH, Monnens LAH, Van den Heuvel LPWJ (1999) Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane. Nephrol Dial Transplant 14:2119-2129
25. Guash A, Deen WM, Myers BD (1993) Charge selectivity of the glomerular filtration barrier in healthy and nephrotic humans. J Clin Invest 92:2274-2282
26. Birmele B, Thibault G, Hubert N (2001) In vitro decrease of glomerular heparan sulfate by lymphocytes from idiopathic nephrotic syndrome patients. Kidney Int 59:913-922
27. Girardin EP, Birmele B, Benador N (1998) Effect of plasma from patients with idiopathic nephrotic syndrome on proteoglycan synthesis by human and rat glomerular cells. Pediatr Res 43:489-495
28. Baggio B, Gambaro G (1993) Antiproteinuric effect of glycosaminoglycans? Nephron 64:643-644
29. Vehaskari VM, Root ER, Germuth FG (1982) Glomerular charge and urinary protein excretion: Effect of systemic and intrarenal polycation infusion in the rat. Kidney Int 22:127-135