Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome

Pediatric Research

Volumn 57, Issue 4, 2005, Pages 500-509

  Macey, Paul M ^a   Macey, Katherine E ^a   Woo, Mary A ^b   Keens, Thomas G ^c   Harper, Ronald M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS OF VARIANCE; ARTICLE; BASAL GANGLION; BRAIN CORTEX; BRAIN REGION; BREATHING RATE; CEREBELLUM CORTEX; CEREBELLUM NUCLEUS; CHEMORECEPTOR; CHILD; CINGULATE GYRUS; CLINICAL ARTICLE; CLUSTER ANALYSIS; COLD PRESSOR TEST; CONGENITAL CENTRAL HYPOVENTILATION SYNDROME; FEMALE; FOREHEAD; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEART RATE; HIRSCHSPRUNG DISEASE; HUMAN; HYPOVENTILATION; INSULA; MALE; MEDULLA OBLONGATA; NERVE POTENTIAL; PRIORITY JOURNAL; SENSORY NERVE; SLEEP; TEMPORAL CORTEX; THALAMUS;

ADOLESCENT; ANIMALS; BRAIN; CHILD; CLUSTER ANALYSIS; COLD; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; HYPOVENTILATION; MAGNETIC RESONANCE IMAGING; MALE; SENSATION; SLEEP APNEA, CENTRAL; TRANSCRIPTION FACTORS;

EID: 15244357861     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000155757.98389.53     Document Type: Article

References (55)

1. Haddad GG, Mazza NM, Defendini R, Blanc WA, Driscoll JM, Epstein MA, Epstein RA, Mellins RB 1978 Congenital failure of automatic control of ventilation, gastrointestinal motility and heart rate. Medicine (Baltimore) 57:517-526
2. Paton JY, Swaminathan S, Sargent CW, Keens TG 1989 Hypoxic and hypercapnic ventilatory responses in awake children with congenital central hypoventilation syndrome. Am Rev Respir Dis 140:368-372
3. Oren J, Kelly DH, Shannon DC 1987 Long-term follow-up of children with congenital central hypoventilation syndrome. Pediatrics 80:375-380
4. Commare MC, Francois B, Estournet B, Barois A 1993 Ondine's curse: a discussion of five cases. Neuropediatrics 24:313-318
5. Kim AH, Macey PM, Woo MA, Yu PL, Keen TG, Gozal D, Harper RM 2002 Cardiac responses to pressor challenges in Congenital Central Hypoventilation Syndrome. Somnologie 6:109-115
6. Woo MS, Woo MA, Gozal D, Jansen MT, Keens TG, Harper RM 1992 Heart rate variability in congenital central hypoventilation syndrome. Pediatr Res 31:291-296
7. Weese-Mayer DE, Berry-Kravis EM, Zhou L, Maher BS, Silvestri JM, Curran ME, Marazita ML 2003 Idiopathic congenital central hypoventilation syndrome: analysis of genes pertinent to early autonomic nervous system embryologic development and identification of mutations in PHOX2b. Am J Med Genet 123A:267-278
8. Amiel J, Laudier B, Attie-Bitach T, Trang H, de Pontual L, Gener B, Trochet D, Etchevers H, Ray P, Simonneau M, Vekemans M, Munnich A, Gaultier C, Lyonnet S 2003 Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome. Nat Genet 33:459-461
9. Gozal D, Marcus CL, Shoseyov D, Keens TG 1993 Peripheral chemoreceptor function in children with the congenital central hypoventilation syndrome. J Appl Physiol 74:379-387
10. Koulchitsky SV, Levkovets VS, Tchitchkan DN, Soltanov VV, Kulchitsky VA 1999 Role of the solitary tract nucleus and caudal ventrolateral medulla in temperature responses in endotoxemic rats. Life Sci 64:37-43
11. Paton JY, Swaminathan S, Sargent CW, Hawksworth A, Keens TG 1993 Ventilatory response to exercise in children with congenital central hypoventilation syndrome. Am Rev Respir Dis 147:1185-1191
12. Shea SA, Andres LP, Shannon DC, Banzett RB 1993 Ventilatory responses to exercise in humans lacking Ventilatory chemosensitivity. J Physiol 468:623-640
13. Spengler CM, Banzett RB, Systrom DM, Shannon DC, Shea SA 1998 Respiratory sensations during heavy exercise in subjects without respiratory chemosensitivity. Respir Physiol 114:65-74
14. American Thoracic Society 1999 Idiopathic congenital central hypoventilation syndrome: diagnosis and management. Am J Respir Crit Care Med 160:368-373
15. Kwong KK, Belliveau JW, Chesler DA, Goldberg IE, Weisskoff RM, Poncelet BP, Kennedy DN, Hoppel BE, Cohen MS, Turner R Cheng HM, Brady TJ, Rosen BR 1992 Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89:5675-5679
16. Friston KJ, Holmes AP, Poline JB, Grasby PJ, Williams SC, Frackowiak RS, Turner R 1995 Analysis of fMRI time-series revisited. Neuroimage 2:45-53
17. Macey PM, Macey KE, Kumar R, Harper RM 2004 A method for removal of global effects from fMRI time series. Neuroimage 22:360-366
18. Macey PM, Macey KE, Henderson LA, Alger JR, Frysinger RC, Woo MA, Yan-Go F, Harper RM 2003 Functional magnetic resonance imaging responses to expiratory loading in obstructive sleep apnea. Respir Physiol Neurobiol 138:275-290
19. Harper RM, Macey PM, Henderson LA, Woo MA, Macey KE, Frysinger RC, Alger JR, Nguyen KP, Yan-Go FL 2003 fMRI responses to cold pressor challenges in control and obstructive sleep apnea subjects. J Appl Physiol 94:1583-1595
20. Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, Gallego J, Brunet JF 2003 Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development 130:6635-6642
21. Macey KE, Macey PM, Woo MA, Harper RK, Alger JR, Keen TG, Harper RM 2004 fMRI signal changes in response to forced expiratory loading in congenital central hypoventilation syndrome. J Appl Physiol 97:1897-1907
22. Littell RC, Milliken GA, Stroup WW, Wolfinger RD 1996 SAS System for Mixed Models. SAS Institute, Cary, NC
23. Holmes AP, Friston KJ 1998 Generalisability, random effects and population inference. Neuroimage 7:S754
24. Ito M 2002 Historical review of the significance of the cerebellum and the role of Purkinje cells in motor learning. Ann NY Acad Sci 978:273-288
25. Lincoln A, Lai Z, Jones W 2002 Shifting attention and joint attention dissociation in Williams syndrome: implications for the cerebellum and social deficits in autism. Neurocase 8:226-232
26. Fatemi SH, Halt AR, Realmuto G, Earle J, Kist DA, Thuras P, Merz A 2002 Purkinje cell size is reduced in cerebellum of patients with autism. Cell Mol Neurobiol 22:171-175
27. Skoyles JR 2002 Is autism due to cerebral-cerebellum disconnection? Med Hypotheses 58:332-336
28. Silvestri JM, Weese-Mayer DE, Nelson MN 1992 Neuropsychologic abnormalities in children with congenital central hypoventilation syndrome. J Pediatr 120:388-393
29. Piven J, Nehme E, Simon J, Barta P, Pearlson G, Folstein SE 1992 Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle. Biol Psychiatry 31:491-504
30. Grillet N, Dubreuil V, Dufour HD, Brunet JF 2003 Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b. J Neurosci 23:10613-10621
31. Hopkins DA, Armour JA 1982 Medullary cells of origin of physiologically identified cardiac nerves in the dog. Brain Res Bull 8:359-365
32. Macey PM, Alger JR, Kumar R, Macey KE, Woo MA, Harper RM 2003 Global BOLD MRI changes to ventilatory challenges in congenital central hypoventilation syndrome. Respir Physiol Neurobiol 139:41-50
33. Xu F, Frazier DT 1997 Respiratory-related neurons of lhe fastigial nucleus in response to chemical and mechanical challenges. J Appl Physiol 82:1177-1184
34. Xu F, Frazier DT 2002 Role of the cerebellar deep nuclei in respiratory modulation. Cerebellum 1:35-40
35. Bassal M, Bianchi AL 1982 Inspiratory onset or termination induced by electrical stimulation of the brain. Respir Physiol 50:23-40
36. Lutherer LO, Williams JL, Everse SJ 1989 Neurons of the rostral fastigial nucleus are responsive to cardiovascular and respiratory challenges. J Auton Nerv Syst 27:101-111
37. Lutherer LO, Lutherer BC, Dormer KJ, Janssen HF, Barnes CD 1983 Bilateral lesions of the fastigial nucleus prevent the recovery of blood pressure following hypotension induced by hemorrhage or administration of endotoxin. Brain Res 269:251-257
38. Dum RP, Li C, Strick PL 2002 Motor and nonmotor domains in the monkey dentate. Ann NY Acad Sci 978:289-301
39. Welsh JP, Yuen G, Placantonakis DG, Vu TQ, Haiss F, O'Hearn E, Molliver ME, Aicher SA 2002 Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus. Adv Neurol 89:331-359
40. Ohtsuka K 1988 Inhibitory action of Purkinje cells in the posterior vermis on fastigio-prepositus circuit of the cat. Brain Res 455:153-156
41. Critchley HD, Corfield DR, Chandler MP, Mathias CJ, Dolan RJ 2000 Cerebral correlates of autonomie cardiovascular arousal: a functional neuroimaging investigation in humans. J Physiol 523(suppl):259-270
42. Oppenheimer SM, Gelb A, Girvin JP, Hachinski VC 1992 Cardiovascular effects of human insular cortex stimulation. Neurology 42:1727-1732
43. Oppenheimer SM, Kedem G, Martin WM 1996 Left-insular cortex lesions perturb cardiac autonomic tone in humans. Clin Auton Res 6:131-140
44. Woo MA, Stevenson WG, Moser DK, Trelease RB, Harper RM 1992 Patterns of beat-to-beat heart rate variability in advanced heart failure. Am Heart J 123:704-710
45. Woo MA, Macey PM, Fonarow GC, Hamilton MA, Harper RM 2003 Regional brain gray matter loss in heart failure. J Appl Physiol 95:677-684
46. King AB, Menon RS, Hachinski V, Cechetto DF 1999 Human forebrain activation by visceral stimuli. J Comp Neurol 413:572-582
47. Harper RM, Bandler R, Spriggs D, Alger JR 2000 Lateralized and widespread brain activation during transient blood pressure elevation revealed by magnetic resonance imaging. J Comp Neurol 417:195-204
48. Hajnik T, Lai YY, Siegel JM 2000 Atonia-related regions in the rodent pons and medulla. J Neurophysiol 84:1942-1948
49. Lai YY, Siegel JM 1988 Medullary regions mediating atonia. J Neurosci 8:4790-4796
50. Magoun H, Rhines R 1946 An inhibitory mechanism in the bulbar reticular formation. J Neurophysiol 9:165-171
51. Mori RL, Bergsman AE, Holmes MJ, Yates BJ 2001 Role of the medial medullary reticular formation in relaying vestibular signals to the diaphragm and abdominal muscles. Brain Res 902:82-91
52. Homma Y, Nonaka S, Matsuyama K, Mori S 1995 Fastigiofugal projection to the brainstem nuclei in the cat: an anterograde PHA-L tracing study. Neurosci Res 23:89-102
53. Morris R 1987 Responses of neurones in the brainstem raphe nuclei to stimulation of the cerebellar fastigial nuclei in the cat. Neurosci Lett 74:19-24
54. Takagi H, Senba E, Shiosaka S, Sakanaka M, Inagaki S, Takatsuki K, Tohyama M 1981 Ascending and cerebellar non-serotonergic projections from the nucleus raphe magnus of the rat. Brain Res 206:161-165
55. Zimny R, Grottel K, Jakielska D 1988 Afferent fiber connections from the raphe nuclei to the cerebellar paramedian lobule. A histochemical study in the rabbit utilizing horseradish peroxidase as a retrograde marker. J Himforsch 29:21-35