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Volumn 96, Issue 3, 2005, Pages 251-253

Predictive model for identifying potential CYP2D6 inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 2D6 INHIBITOR; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

EID: 15244357615     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto960320.x     Document Type: Conference Paper
Times cited : (10)

References (7)
  • 2
    • 0032849040 scopus 로고    scopus 로고
    • A. Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors
    • Ekins, S., G. Bravi, S. Binkley, J. S. Gillespie, B. J. Ring, J. H. Wilkel & S. Wrighton: A. Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors. Pharmacogenetics 1999, 9, 477-489.
    • (1999) Pharmacogenetics , vol.9 , pp. 477-489
    • Ekins, S.1    Bravi, G.2    Binkley, S.3    Gillespie, J.S.4    Ring, B.J.5    Wilkel, J.H.6    Wrighton, S.7
  • 3
    • 2442659094 scopus 로고    scopus 로고
    • Incorporating molecular shape into the alignment-free GRid-INdependent descriptors
    • Fontaine, F., M. Pastor & F. Sanz: Incorporating molecular shape into the alignment-free GRid-INdependent descriptors. J. Med. Chem. 2004, 47, 2805-2815.
    • (2004) J. Med. Chem. , vol.47 , pp. 2805-2815
    • Fontaine, F.1    Pastor, M.2    Sanz, F.3
  • 4
    • 0026046988 scopus 로고
    • A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation
    • Islam, S. A., C. R. Wolf, M. S. Lennard & M. J. E. Sternberg: A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation. Carcinogenesis 1991, 12, 2211-2219.
    • (1991) Carcinogenesis , vol.12 , pp. 2211-2219
    • Islam, S.A.1    Wolf, C.R.2    Lennard, M.S.3    Sternberg, M.J.E.4
  • 5
    • 0034710718 scopus 로고    scopus 로고
    • GRid-INdependent Descriptors (GRIND): A novel class of alignment-independent three-dimensional descriptors
    • Pastor, M., G. Cruciani, I. McLay, S. Pickett & S. Clementi: GRid-INdependent Descriptors (GRIND): a novel class of alignment-independent three-dimensional descriptors. J. Med. Chem. 2000, 43, 3233-3243.
    • (2000) J. Med. Chem. , vol.43 , pp. 3233-3243
    • Pastor, M.1    Cruciani, G.2    McLay, I.3    Pickett, S.4    Clementi, S.5
  • 7
    • 0027314831 scopus 로고
    • Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: Molecular modeling and inhibition studies
    • Strobl, G. R., S. von Kruedener, J. Stöckigt, F. P. Guengerich & T. Wolff: Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies. J. Med. Chem. 1993, 36, 1136-1145.
    • (1993) J. Med. Chem. , vol.36 , pp. 1136-1145
    • Strobl, G.R.1    Von Kruedener, S.2    Stöckigt, J.3    Guengerich, F.P.4    Wolff, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.